Protein ANGEL2

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSCINP00000014202	pdb,4u09,B,#1	25	133	5.19e-15	45.536
ENSCINP00000014202	pdb,4u09,A,#1	25	133	5.89e-15	45.536
ENSACAP00000011884	pdb,4u09,B,#1	26	155	1.99e-14	39.695
ENSACAP00000011884	pdb,4u09,A,#1	26	132	2.09e-14	43.519
ENSDORP00000018187	pdb,4u09,B,#1	26	132	2.67e-14	38.889
ENSDORP00000018187	pdb,4u09,A,#1	26	132	3.24e-14	38.889
ENSGMOP00000011857	pdb,4u09,A,#1	29	118	3.35e-14	43.333
ENSGMOP00000011857	pdb,4u09,B,#1	29	118	3.49e-14	43.333
ENSTBEP00000014865	pdb,4u09,A,#1	26	127	6.54e-14	39.806
ENSOPRP00000014776	pdb,4u09,A,#1	63	169	7.04e-14	41.667
ENSOPRP00000014776	pdb,4u09,B,#1	63	169	8.4e-14	41.667

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.028	0.053	0.918	0.011	0.362	0.627

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.0812441968430826	0.100742804085422	0.0937790157845868	0.0468895078922934	0.0343546889507892	0.0255338904363974	0.0250696378830084	0.59238625812442

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.021199527 1.888575350 2.681054879 16.288256630 0.001832000 6.309529601 40.092154822 0.060573760 0.015756798 4.855525930 28.933104829 0.003565411 0.043871157 0.312321335 0.129458986 33.981429626 0.100370211 0.092425482 0.386017537 4.154315495 5.203257696 79.016630652 0.000043558 0.026767950 0.024038111 0.134727342 6.161944886 0.325260206 7.813402109 0.000419745 0.001824911 0.021300350 0.062484771 0.476546709 0.316980331 6.096353030 12.408379984 0.005443265 0.000909187 0.047530195 0.071148908 0.121722757 0.232879052 0.035777895 5.308582727 26.521792428 0.001712159 0.019236908 0.007307705 0.099815197 0.304252306 0.032346234 0.054665833 0.066736510 5.303123018 36.862169172 0.019406109 0.010208293 0.039291541 0.028315456 0.196178144 0.073968138 0.260094997 0.031995950 0.031832595 6.571158546 69.834558779 0.000565471 0.005468545 0.027579077 0.302582355 0.066295863 0.038370364 0.212453369 0.047626265 0.126252793 0.245464177 13.477622753 54.314619543 0.004349345 0.027649493 0.001717671 0.638093888 0.002941877 0.002687412 0.013264634 0.180614478 0.003092341 0.200060197 0.033890734 22.920020847 52.216979658 0.000000001 0.264391387 0.004010105 0.001654154 0.262765860 0.000575005 0.000150710 0.000357035 0.000003799 0.003078966 0.223215512 1.012613092 83.998225255 814.368364504 0.000000007 0.606385599 0.075371922 0.065226017 0.893151685 0.004496181 1.006013188 0.052613883 0.001793472 0.301240052 0.548708734 2.062975475 3.882375055 181.462867020 39.249685727 0.000000935 1.245626490 0.000145218 0.000018905 0.211747128 0.195218149 0.000188096 0.532371912 0.205401890 0.303189222 0.000145084 0.000039191 0.000021615 0.216789339 70.168553264 0.879967984 0.000000008 0.000049849 0.000001420 1.015781600 0.000011707 0.149390373 0.000000352 0.019890868 0.760392276 0.000233060 1.063147397 0.000000845 3.451802667 0.510270225 13.447211653 761.012974356 53.181552691 0.269801178 1.109228304 2.039334487 0.226003461 0.028908154 0.018320914 1.126049015 0.292146738 0.032295328 0.003693418 0.000177395 0.000188509 16.238043147 75.768564141 171.131330462 65.932417616 197.867031325 502.171671406 0.000000777 0.007530342 0.156522143 0.096514554 0.091627642 0.376347338 0.115311180 0.010534525 0.135143336 0.104660912 0.081544251 2.184880787 21.853297212 2.281699601 121.810146673 166.717427057 0.114807955 442.464900729 0.000004160 0.090110800 0.065782400 0.060308400 0.102271000 0.096178400 0.117695000 0.087308100 0.104186000 0.098869100 0.083061000 0.053145500 0.026670700 0.009150610 0.002128970 0.000669106 0.000656680 0.000567472 0.000555852 0.000681286