Protein CARS2

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSTNIP00000017501	pdb,1u0b,B,#1	55	490	7.58e-90	36.607
ENSAMXP00000008398	pdb,1u0b,B,#1	40	453	1.83e-86	38.425
ENSTRUP00000013323	pdb,1u0b,B,#1	43	456	4.38e-85	37.381
ENSPFOP00000019066	pdb,1u0b,B,#1	39	484	7.07e-85	38.022
ENSMAUP00000023090	pdb,1u0b,B,#1	37	445	8.39e-85	39.277
ENSGACP00000020177	pdb,1u0b,B,#1	47	486	1.86e-84	36.947
ENSGMOP00000005319	pdb,1u0b,B,#1	6	373	2.55e-84	38.802
ENSONIP00000004690	pdb,1u0b,B,#1	57	470	3.43e-84	37.947
ENSMOCP00000000666	pdb,1u0b,B,#1	37	445	4.03e-84	38.702
ENSPEMP00000022396	pdb,1u0b,B,#1	37	483	6.66e-84	37.528
MGP_PahariEiJ_P0046599	pdb,1u0b,B,#1	37	445	1.21e-83	38.313

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.019	0.028	0.953	0.034	0.526	0.439

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.243194192377495	0.315789473684211	0.159709618874773	0.0526315789473684	0.00635208711433757	0.00816696914700544	0.00362976406533575	0.210526315789474

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

1.748552573 0.002264083 2.339684289 0.555412699 0.000030289 5.524648476 1.382659041 0.030021021 0.120529256 6.703919850 0.000000101 0.007729410 0.078049846 0.024644281 0.227484615 0.000000292 0.076478447 0.383130416 0.204595312 6.245147457 8.480567885 0.000000101 0.000054811 0.007478359 0.049853051 0.275562848 7.750152187 0.173554531 0.000000101 0.000000001 0.014869775 0.011337158 0.110623056 0.661642360 0.148810609 7.040636810 0.000000101 0.004824186 0.000040618 0.000047710 0.006184873 0.147107049 0.371790772 0.058034064 5.669228725 0.000000101 0.000000001 0.000000001 0.000097603 0.000828878 0.295362788 0.026419493 0.079138555 0.031073049 5.184309802 0.000000101 0.004265969 0.009152713 0.034976213 0.007322462 0.072988275 0.098154274 0.170143843 0.006657966 0.002952828 6.096367620 0.000000101 0.033201197 0.069891618 0.007462768 0.154959160 0.005624888 0.150082130 0.053306378 0.149407957 0.181912649 0.017596780 8.648463911 0.000000101 0.060496241 0.000000026 0.000000549 0.034936889 0.149737959 0.078211466 0.104120876 0.123239004 0.229174159 0.216060217 0.009264944 18.282776079 0.000000101 0.000000007 0.030623553 0.015228052 0.485766071 0.074902799 0.000000014 0.000000086 0.127423847 0.150596843 0.133206095 0.540100329 4.829714176 25.644408224 0.000000101 0.000000009 0.063800401 0.035651134 0.327745826 0.002694793 0.000000673 0.096332216 0.028295662 1.182154096 0.283425677 3.247304834 1.784611207 6.004303978 90.496928366 0.000000101 0.769207574 2.265391869 1.001249300 0.037816607 0.212055305 0.000744448 2.627670846 1.232166670 2.702965929 0.029931840 0.148471311 0.592794387 25.783799385 0.723159104 308.093397617 0.000000101 0.000152454 1.197581704 0.000328685 0.000004496 0.000001871 0.000005608 0.090770926 6.120883564 0.011806667 0.000618893 3.317721884 1.190980282 0.000092072 7.353923631 0.309321433 4.242010001 0.000000101 0.123312995 0.000000003 0.000000032 0.000000003 0.000007724 0.673485225 0.098840721 0.140766875 0.078095134 1.266982166 0.000162145 7.460165906 0.150291176 0.024466286 66.694983464 3.705591512 605.825400889 0.000000101 0.000000001 0.000000001 0.195149679 0.000000003 0.000759000 0.000034980 0.548847544 0.061405066 0.007725985 0.262070219 0.168294607 4.268852761 7.063074076 10.740296322 44.490735945 1.141445822 0.073366188 291.521844019 0.000994005 0.127015000 0.083778000 0.073801300 0.084414500 0.085749800 0.091622500 0.080601800 0.089537400 0.098158100 0.088600300 0.051351200 0.022832200 0.011779800 0.004316920 0.001254850 0.000857353 0.000343736 0.001098470 0.001893090