Protein CISD1

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSCSAP00000003554	pdb,3ew0,A,#1	36	110	9.61e-53	98.667
ENSDORP00000013170	pdb,3ew0,A,#1	36	110	1.22e-52	97.333
ENSMPUP00000010324	pdb,3ew0,A,#1	31	105	2.6e-52	94.667
ENSOCUP00000002562	pdb,3ew0,A,#1	33	107	4.88e-52	93.333
ENSCSAP00000003554	pdb,3ree,A,#1	35	107	5.57e-52	100
ENSDORP00000013170	pdb,3ree,A,#1	35	108	7.74e-52	97.297
ENSCSAP00000003554	pdb,2r13,A,#1	36	107	1.71e-51	100
ENSDORP00000013170	pdb,2r13,A,#1	36	108	1.83e-51	97.26
ENSCAFP00000018074	pdb,3ew0,A,#1	28	102	1.87e-51	93.333
ENSMPUP00000010324	pdb,3ree,A,#1	30	103	1.96e-51	94.595
ENSCSAP00000003554	pdb,3ew0,B,#1	36	107	2e-51	100

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.096	0.218	0.686	0.195	0.239	0.566

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.388127853881279	0.0730593607305936	0.0365296803652968	0.0365296803652968	0.0319634703196347	0.0228310502283105	0	0.410958904109589

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.491733444 0.000000023 2.321598853 1.477060687 0.001251718 4.023341697 0.000000023 0.286921790 0.128413789 4.388087464 0.000000891 0.157092669 0.318128247 0.702182671 2.855538523 2.007182322 0.149604469 0.006663569 0.684671721 4.202627642 6.523529175 0.000075740 0.000011013 0.273490123 0.310064107 0.732771265 4.887863711 0.340668644 0.744405515 0.035764653 0.068827261 0.815397148 0.463081414 1.832848311 0.904960359 7.082606877 0.000005504 0.010491366 0.339373432 0.082843755 0.386213336 1.235165094 0.108439436 2.566908997 4.908687414 1.840364321 0.083253869 0.190849737 0.664175159 0.026633178 0.370583949 0.308386603 0.165789558 2.782565006 6.889349279 0.000000027 0.001152716 0.002741174 0.000504744 0.374554738 0.104668434 0.381541728 0.274880175 0.068031538 0.261375510 6.419484545 0.000000023 0.058105455 0.023898116 0.614419347 0.104030791 0.459409360 0.147165743 0.433856596 0.372670328 1.448159625 2.495438845 8.027066559 0.000000023 0.014311227 0.000001106 0.045527683 0.013953079 0.428007325 0.438125131 0.034059575 0.072401312 0.623760165 0.031547250 0.045960033 13.549103566 0.000000023 0.074922029 0.089490935 0.000084032 0.620583683 0.000000532 0.127781424 0.000000037 1.319007351 0.000000002 0.011627332 1.471233214 0.668457457 12.845732739 0.000000023 0.000000001 0.000000001 0.000000001 0.000000002 0.000000001 0.111899644 0.000000002 0.000000002 0.443538515 0.000054369 0.259295952 1.308212563 0.557857593 6.266785691 0.000000023 0.000000001 0.000000001 0.081361969 0.000000002 0.000025592 0.291891998 0.145515650 0.000000677 0.387138156 0.213975733 0.212996497 0.008775949 3.478190865 0.002253654 4.336948282 0.000000023 0.000000001 0.000000001 0.000000007 0.000000032 0.000006306 1.679896697 0.006494338 0.000713619 1.099576358 0.005434966 0.920597907 2.005031869 7.314643892 0.000000007 4.388924127 10.326227996 0.000000023 0.170958356 0.267809308 0.017767141 0.000001633 0.000000001 0.000000194 1.336479879 0.001150800 0.072380434 0.000000002 1.072247587 0.000000013 0.000000008 0.000002110 0.309365347 0.000000496 29.078554219 0.000000023 0.000000001 0.000000001 0.000000002 0.543173388 0.191179297 0.406542056 0.000000023 0.378605056 0.000006869 1.901337348 0.075250361 0.000167533 0.091763916 4.579666094 5.622921147 4.602650628 10.239800232 13.884980980 0.004284130 0.167370000 0.113188000 0.076232300 0.054406200 0.067110300 0.060947200 0.062174000 0.063490700 0.061348900 0.056455000 0.064197300 0.044933600 0.022048100 0.013554700 0.019391700 0.024507400 0.005358210 0.009460870 0.009541170