Protein ECHS1

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSHGLP00000005348	pdb,2zqq,C,#1	72	337	0	96.992
ENSDNOP00000007459	pdb,2gtr,A,#1	286	543	0	99.225
ENSJJAP00000015906	pdb,1dub,A,#1	29	287	0	93.05
ENSDORP00000020945	pdb,1dub,A,#1	32	291	0	92.308
ENSCATP00000035751	pdb,2vx2,D,#1	45	300	0	97.656
ENSOARP00000000051	pdb,2gtr,A,#1	288	545	0	97.287
ENSSHAP00000010186	pdb,2gtr,B,#1	287	544	0	93.798
ENSFDAP00000003955	pdb,2gtr,A,#1	314	571	0	96.512
ENSGGOP00000004627	pdb,2hw5,B,#1	31	290	0	98.077
ENSOGAP00000004735	pdb,1ey3,A,#1	30	287	0	92.636
ENSMFAP00000030732	pdb,2hw5,C,#1	28	287	0	96.154

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.073	0.243	0.684	0.022	0.308	0.67

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.0530839231547017	0.076845298281092	0.0303336703741153	0.0353892821031345	0.0338725985844287	0.0182002022244692	0.0121334681496461	0.740141557128413

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.627855126 0.074139352 1.439213986 0.009510839 0.198452040 4.138045625 0.168931999 0.281168108 1.019178816 3.944815461 0.000020126 0.107157539 0.395727306 0.642729756 1.461077106 0.396084013 0.549152023 0.874691533 2.041293542 4.614253107 4.837340953 0.000009741 0.013559934 0.123206582 0.542128330 1.061223790 4.828058871 1.663537763 0.000000005 0.013795753 0.126059404 0.255603197 0.601900049 1.871432368 0.759018125 4.716290421 0.008141956 0.022968181 0.041823849 0.179855683 0.321105483 0.736117688 0.568651893 1.292090346 4.550274213 0.000000005 0.026227418 0.039861659 0.040858124 0.200780034 0.435526630 0.237203411 0.634688369 1.552178960 4.840466356 0.000000005 0.013188229 0.025876785 0.053101205 0.036853953 0.239924286 0.299985482 0.335335578 0.802113349 1.180731525 4.663892020 0.000000005 0.013259012 0.011023880 0.036979206 0.058930023 0.142776773 0.180926956 0.207328333 0.343134390 0.671217379 1.626592730 6.153460519 0.000000005 0.047476474 0.006657508 0.056180909 0.111422500 0.012027352 0.092366102 0.186217604 0.166124193 0.457102513 0.657499771 1.357963284 6.831839238 0.000562602 0.014820052 0.000039516 0.000659283 0.242884071 0.131982979 0.717450019 0.182460811 0.223511443 0.067800929 0.355825843 0.344262574 1.099445670 3.824831593 0.000000005 0.088926593 0.023465972 0.000821839 0.187960875 0.209227307 0.369106711 0.139623021 0.363817393 0.095247149 0.295039152 0.523473936 0.747799786 2.758992416 4.634387809 0.000000005 0.048356890 0.088661945 0.218314424 0.201444914 0.120864988 0.004484482 0.069228860 0.403357116 0.285716237 0.007987593 0.768784319 0.462377553 0.240901066 3.260411510 10.973362113 0.000000005 0.025435873 0.004025813 0.000052581 0.138407441 0.242636057 0.463637137 0.205438856 0.197478105 0.333700520 1.135764297 0.385356851 0.636100506 0.846268406 2.842942086 0.009754595 5.636668037 0.000000005 0.000514835 0.000033783 0.000065528 0.150527449 0.282323705 0.134345096 0.261678488 0.249977679 0.165502184 0.232454831 0.176123564 0.963896136 1.114955963 0.438961360 0.502506581 3.532037964 7.782104506 0.000000135 0.082341598 0.264944891 0.154857580 0.358741800 0.015765239 0.242898015 0.479287406 0.383411390 0.807132691 0.611683983 1.019655093 0.762773623 1.925516071 2.113438959 0.979675355 2.805325018 8.350640246 12.717063997 0.022201300 0.133789000 0.064998800 0.063249600 0.072945500 0.074121300 0.079900200 0.067690700 0.073920600 0.080522200 0.082052500 0.076397500 0.047643100 0.020278200 0.008424090 0.008014900 0.005304020 0.005477580 0.005359940 0.007708760