Protein MALSU1

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSTGUP00000002849	pdb,3ups,A,#1	4	111	1.16e-16	34.259
ENSFALP00000010034	pdb,3ups,A,#1	4	111	1.29e-16	33.333
ENSSHAP00000008752	pdb,3ups,A,#1	6	113	1.72e-15	35.185
ENSPEMP00000023412	pdb,3ups,A,#1	6	108	4.34e-15	36.449
ENSOPRP00000009566	pdb,3ups,A,#1	6	108	5e-15	36.449
ENSOANP00000022394	pdb,3ups,A,#1	40	145	1.51e-14	31.132
ENSPSIP00000015816	pdb,3ups,A,#1	12	110	3.32e-14	35.354
ENSMGAP00000010897	pdb,3ups,A,#1	6	107	4.44e-14	30.392
ENSCGRP00001005899	pdb,3ups,A,#1	79	181	5.24e-14	37.383
ENSECAP00000013657	pdb,3ups,A,#1	37	139	7.09e-14	35.514
ENSCLAP00000012270	pdb,3ups,A,#1	22	126	7.47e-14	32.381

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.046	0.063	0.891	0.098	0.384	0.518

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.386581469648562	0.293929712460064	0.10223642172524	0.00319488817891374	0.00319488817891374	0.00319488817891374	0.00638977635782748	0.201277955271566

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.007162292 0.788121020 1.529112442 15.657910608 0.107583757 5.171325324 18.145392012 0.001573243 0.223639229 5.863419378 48.493593015 0.119341874 0.245527508 0.157268443 0.081848365 93.353158954 0.032445850 0.038135162 1.472168273 5.889892502 5.311250059 129.031699343 0.000005369 0.007119377 0.338161507 0.076768651 5.216817494 0.782257369 14.888871362 0.007505888 0.095570083 0.290262567 0.180419361 0.398445920 0.223503132 6.415319427 39.491647568 0.002424495 0.000163291 0.010242272 0.023755398 0.120017458 0.337191624 0.365364325 3.154300139 21.917054055 0.000000001 0.000000381 0.075504035 0.027270627 0.329287987 0.006951567 0.382852991 0.370704139 3.663261890 3.574905898 0.013533796 0.000000975 0.181307264 0.000002320 0.154606844 0.010727772 0.011279397 0.572776833 0.012250882 7.594708838 0.422199128 0.000000001 0.000000001 0.000000005 0.000000001 0.283257177 0.000691276 0.073973773 0.019788550 0.114391874 0.361330629 6.579131415 0.189908419 0.000021099 0.000000001 0.000000124 0.000000001 0.031692157 0.000022774 0.217191842 0.000784036 0.000471204 0.182752795 0.000001695 8.811406495 0.460690525 0.000000001 0.000000001 0.000000001 0.000000001 0.874195263 0.000000001 0.008764688 0.000033533 1.474631548 0.004562000 1.093209508 0.644742366 44.361162595 0.000015465 1.155367677 0.000000001 0.000000001 1.334397891 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 3.336264173 0.076197458 0.000000006 129.747085078 58.534295850 0.000000001 0.000000254 0.000030317 0.007475284 2.567114036 0.592377512 0.000032559 0.000038015 1.107881674 3.158776939 0.000472226 0.000000060 0.000000006 0.000003404 0.000000115 0.000015465 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.476841201 0.562447012 0.248151524 0.000000006 0.000019196 0.000003243 40.403220522 0.000015465 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.281722329 0.000000001 0.006028440 0.000000002 0.000000002 0.000010498 24.428986610 70.252561545 0.000000115 145.763747697 0.000338086 0.000000001 0.000000001 0.000000001 0.000000011 0.000000001 0.000000001 0.000000001 1.010175125 1.691762546 0.955954218 0.003299534 2.305597310 0.000000030 0.000001368 0.000005759 100.929757173 9.607021268 50.173584185 0.000006466 0.088828000 0.071755300 0.072187400 0.082225100 0.086379100 0.083534400 0.077621700 0.087075100 0.104559000 0.090324200 0.079499400 0.045970300 0.016779700 0.002890300 0.000871154 0.000869797 0.003354380 0.003352840 0.001916310