Protein NOA1

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSVPAP00000000436	pdb,3ec1,B,#1	213	607	1.01e-26	25
ENSVPAP00000000436	pdb,3ec1,A,#1	213	607	1.01e-26	25
ENSOANP00000029100	pdb,3ec1,B,#1	473	658	5.28e-23	33.871
ENSOANP00000029100	pdb,3ec1,A,#1	473	658	5.28e-23	33.871
ENSMODP00000025897	pdb,3ec1,B,#1	467	646	8.58e-23	35
ENSMODP00000025897	pdb,3ec1,A,#1	467	646	8.58e-23	35
ENSTSYP00000033651	pdb,3ec1,A,#1	209	436	9.35e-23	29.87
ENSTSYP00000033651	pdb,3ec1,B,#1	209	436	9.35e-23	29.87
ENSORLP00000025389	pdb,3ec1,A,#1	382	549	1.41e-21	34.911
ENSORLP00000025389	pdb,3ec1,B,#1	382	549	1.41e-21	34.911
ENSPSIP00000003100	pdb,3ec1,B,#1	283	451	1.63e-21	33.728

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.025	0.071	0.904	0.3	0.377	0.323

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.355113636363636	0.270833333333333	0.03125	0.00284090909090909	0.00473484848484848	0.00378787878787879	0.00284090909090909	0.328598484848485

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.034303119 1.346318122 2.651889760 8.591673890 0.000000517 6.354064041 114.600180497 0.058316995 0.005185591 5.830959053 37.167934020 0.001013128 0.124473186 0.008275357 0.049595216 67.994781661 0.193513867 0.135831251 0.414132189 6.318381794 7.492919442 203.126089016 0.000684487 0.262075447 0.098178198 0.122117009 8.382505267 0.135450428 13.392769383 0.000733295 0.023176284 0.141911020 0.010835803 0.280362585 0.073511046 6.435441776 34.789300617 0.009099890 0.000270199 0.000519162 0.033703279 0.016384987 0.134314323 0.113481032 5.141962222 76.195794948 0.000332262 0.003009489 0.000339972 0.257445906 0.168856302 0.066133676 0.192647088 0.024688688 4.235635409 43.322580933 0.010838557 0.032390106 0.000014741 0.109215543 0.059205226 0.040824933 0.113512189 0.046405585 0.008290452 4.201419224 8.458132657 0.020997151 0.001033137 0.024238985 0.187256069 0.021640112 0.218770133 0.000163096 0.210556924 0.103516573 0.045685958 7.290733004 0.025101954 0.048908833 0.109090084 0.237099555 0.000000001 0.266663081 0.000000001 0.000000636 0.143418514 0.186697806 0.022449475 0.000007920 18.019844347 0.025257253 0.000000001 0.000000002 0.000000002 0.000082787 0.494589503 0.000000001 0.000000030 0.814614488 0.000134478 0.000000060 0.071925307 0.825809944 50.145098076 0.000044678 0.000000001 0.000000002 0.000000023 0.000000001 0.000000001 0.000000001 0.000000001 0.003700873 0.000082303 0.000000058 0.808898595 0.000083620 0.505376885 381.514451923 366.453405771 0.000000055 0.000765535 0.002252648 0.015257639 0.031407780 0.002884987 0.252619669 0.084712752 3.625791078 0.015762448 0.011833207 0.004939668 0.102826044 1.474415662 0.826176047 0.000044678 0.000000001 0.000022907 0.000856101 0.849302285 0.000000001 0.000000001 0.000000001 0.000000001 0.000000001 0.000002879 0.000000130 0.000024267 14.913121459 59.663810195 0.000098819 49.438578905 0.001141874 0.000000001 0.000277840 0.660444009 0.000000053 0.000000001 0.000000001 0.000049426 0.000000001 0.000000004 0.005608916 0.242242056 0.000009439 0.003966283 0.599364794 76.765254540 111.675606009 278.050956034 56.153887395 0.400414137 0.000034868 0.022173571 0.000178729 0.000399900 0.000361893 0.106233444 0.639430661 0.375150013 1.663382937 0.378549183 0.325507338 23.023240366 0.077840820 0.011883028 10.046540995 0.296081802 219.977524041 0.000002238 0.086251700 0.059480200 0.059561900 0.081759700 0.079937200 0.080714400 0.081842400 0.104718000 0.115823000 0.110342000 0.078990000 0.042299200 0.010537700 0.001533360 0.001034610 0.000307256 0.001233220 0.002108920 0.001522760