Protein SIRT5

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSMICP00000044055	pdb,4g1c,A,#1	36	302	0	93.633
ENSMOCP00000007066	pdb,4f56,B,#1	32	302	0	90.037
ENSSTOP00000015219	pdb,4if6,A,#1	90	366	0	100
ENSPCOP00000002415	pdb,3riy,A,#1	32	302	0	92.989
ENSDORP00000020318	pdb,4kxq,A,#1	137	413	0	99.278
ENSNGAP00000001781	pdb,4hda,A,#1	33	299	0	91.011
ENSAMEP00000000520	pdb,4g1c,A,#1	36	302	0	92.135
ENSCATP00000004356	pdb,4hda,B,#1	34	287	0	98.031
ENSPEMP00000015250	pdb,4kxq,A,#1	90	366	0	99.278
ENSANAP00000017030	pdb,4f56,B,#1	34	287	0	96.457
ENSAMEP00000000520	pdb,4f56,B,#1	34	302	0	92.193

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.022	0.146	0.832	0.004	0.319	0.676

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.106856634016028	0.228851291184328	0.0382902938557435	0.0667853962600178	0.0667853962600178	0.0463045414069457	0.0365093499554764	0.409617097061443

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.982555884 0.025095767 2.226851656 0.022014256 0.095890050 4.236481796 0.163283193 0.325906970 0.647188368 4.884546861 0.000002185 0.077258858 0.235317032 0.427758763 0.447737919 0.471124473 0.260340087 0.370817263 1.234194055 5.025538424 5.580035271 0.000000017 0.003570125 0.031377854 0.133185452 0.548859940 4.694426209 0.728156200 0.000607752 0.035751872 0.071056387 0.285903777 0.295304985 1.256899784 0.481004651 5.449605499 0.000000017 0.035166025 0.075755168 0.085640443 0.220544343 0.257339279 0.481254150 0.472069076 4.827450020 0.000000017 0.013870268 0.042436169 0.013392955 0.239816684 0.366066859 0.206087783 0.161702128 0.650608546 3.770762182 0.000000256 0.011711293 0.048324398 0.014819963 0.040766063 0.182278918 0.191271887 0.151527211 0.250776666 0.494695471 3.477985250 0.000000017 0.000606425 0.058535560 0.013449080 0.150230934 0.061013647 0.163032112 0.176215855 0.067077975 0.608451536 0.848055055 5.574378995 0.000000017 0.032395556 0.010527114 0.080578477 0.348364676 0.099180399 0.421682443 0.213478424 0.109185436 0.089858178 0.309721845 0.259751952 6.626717622 0.000000017 0.034907576 0.000800775 0.001008385 0.315877356 0.051393169 0.479423125 0.079641958 0.156132886 0.011473141 0.176853062 0.127724367 0.066605700 5.675974990 0.000000017 0.000000001 0.169245796 0.071240057 0.490015714 0.008151203 0.501917600 0.089398300 0.046649301 0.640664720 0.006340618 0.001907314 0.169839254 1.197952930 4.682562955 0.000000017 0.063183311 0.045014463 0.000003928 0.298525242 0.170059304 0.458187054 0.000409176 0.339789817 0.017472693 0.000024732 0.000022469 0.087824962 1.618818937 0.389784633 6.372295181 0.000000017 0.039449826 0.130661640 0.015761092 0.154444103 0.421037040 0.282230060 0.000000184 0.032976626 0.211928301 0.045858102 0.291430747 0.001885747 1.209231182 0.564736097 3.478660646 0.955561089 0.000000017 0.017328511 0.014708404 0.007485817 0.370658990 0.111081379 0.361859874 0.433069869 0.013555055 0.000052908 0.029761969 0.398909368 0.270311430 0.171364862 0.000000011 3.386157515 0.927711865 18.316284677 0.000000017 0.000000001 0.000005629 0.000489601 0.529252155 0.040167425 0.411238921 0.254662344 0.031304595 0.083536917 0.003918757 0.218000744 0.125990266 0.588991910 0.410575748 2.969908022 4.731303425 1.690918017 21.488535408 0.005774440 0.070923000 0.051856000 0.051189600 0.067075400 0.071900800 0.073346900 0.071863000 0.092671700 0.096888900 0.121623000 0.112962000 0.065992400 0.020136100 0.009173630 0.003425830 0.003654680 0.003218240 0.002739740 0.003585330