Protein SLC25A35

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSPCAP00000000050	pdb,2lck,A,#1	12	301	1.09e-38	32.566
ENSFDAP00000005342	pdb,2lck,A,#1	26	308	1.15e-38	33.11
ENSLAFP00000003765	pdb,2lck,A,#1	26	308	9.35e-38	32.66
ENSSSCP00000056835	pdb,2lck,A,#1	26	308	2.54e-37	32.997
ENSFCAP00000034295	pdb,2lck,A,#1	26	308	4.26e-37	32.323
ENSECAP00000011168	pdb,2lck,A,#1	19	301	4.36e-37	31.65
ENSCLAP00000003711	pdb,2lck,A,#1	26	308	6.22e-37	31.65
ENSPANP00000005739	pdb,2lck,A,#1	12	294	7.61e-37	31.987
ENSHGLP00000012876	pdb,2lck,A,#1	26	308	8e-37	31.987
ENSTSYP00000033286	pdb,2lck,A,#1	12	294	9.2e-37	31.987
ENSGMOP00000008719	pdb,2lck,A,#1	47	324	9.89e-37	32.632

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.142	0.199	0.659	0.128	0.423	0.449

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.587606837606838	0.0662393162393162	0.014957264957265	0.0192307692307692	0.00641025641025641	0.00213675213675214	0.00213675213675214	0.301282051282051

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.000112232 0.000066341 1.618268178 0.001122828 0.000003690 5.304106479 15.306804259 0.099999212 0.000217316 7.225875152 0.525952213 0.060191173 0.000087597 0.032935082 0.024146840 7.295321083 0.249957858 0.268398849 0.221703969 4.828581254 8.369622182 17.387165570 0.030838381 0.155697277 0.081324648 0.005556145 9.234483331 0.000453412 1.060899276 0.000086351 0.005280771 0.726229146 0.202804169 0.138811646 0.009661441 15.437122962 0.011448224 0.005150607 0.039635713 0.000316158 0.032115715 0.025795343 0.658219241 0.000065540 15.833994037 9.032128572 0.011613038 0.000001494 0.000000002 0.154943715 0.000966331 0.000765322 0.011743284 0.003582779 11.790135301 0.281677783 0.001530602 0.211905880 0.000000023 0.001005500 0.002914339 0.028110829 0.564535967 0.781034005 0.002708325 11.641711736 12.070070649 0.013483415 0.035102047 0.208768311 0.000156857 0.105778533 0.335340785 0.102507705 0.768470103 0.000071941 0.004086548 14.574976909 0.000183690 0.000728553 0.000000001 0.013606117 0.000013202 0.000154946 0.407229957 0.000001818 0.426759214 0.065504951 0.021717705 0.003708771 18.722942669 0.011060108 0.095151749 0.000000001 0.000000002 0.000000004 0.000179125 0.002710686 0.000832448 0.030498227 2.401635007 1.099692097 3.710331266 0.054165794 72.393344157 0.554661461 0.000000007 1.508886169 0.000011475 0.839391605 0.004838010 1.001013354 0.000157023 0.002572803 0.002537149 0.005837576 0.000183529 0.001916465 2.170405433 313.776317162 0.504350976 0.000000092 1.893057104 0.001497052 0.000472970 0.000666208 0.026144898 0.000575240 2.368558143 0.156548654 2.640539813 2.205097017 0.000244199 0.000006487 10.258482278 457.455276641 0.013945351 0.000000000 0.000023746 0.000013013 5.452812734 9.030997540 0.009364499 0.004683165 0.896867050 9.382744045 0.000290874 3.308574423 3.425768562 49.679860968 3.800665827 0.158189943 0.000419230 0.212878103 0.031852339 0.000032269 0.000000080 1.655700655 0.001813216 0.348484301 0.000000070 0.000017188 0.000001071 0.000000884 1.019643549 3.409333288 3.766748226 5.069515096 5.380638556 112.745084755 3.694282422 39.019785008 0.000000003 0.000000001 0.000000002 0.001051973 0.015935210 0.271624640 0.000248736 0.000002709 0.000281719 1.299783813 0.019648807 0.784254764 0.029527947 49.871331670 101.518219090 0.030371404 0.000754645 107.443751759 0.000764771 0.253906000 0.093893100 0.052119500 0.078804100 0.069837800 0.083090400 0.063173300 0.041117800 0.051596100 0.068690500 0.057056900 0.041070200 0.026238600 0.005848370 0.002168330 0.001476020 0.001961320 0.002523190 0.004663470