Protein TTC19

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSPSIP00000006418	pdb,3ceq,B,#1	149	267	6.72e-09	30.469
ENSFALP00000006378	pdb,3ceq,B,#1	153	271	5.71e-08	30.469
ENSTBEP00000012267	pdb,3ceq,B,#1	332	484	1.24e-07	28.313
ENSOCUP00000009002	pdb,3ceq,B,#1	117	258	3.32e-07	28.188
ENSAMEP00000004823	pdb,3ceq,B,#1	183	324	3.44e-07	28.188
ENSMPUP00000010133	pdb,3ceq,B,#1	138	279	8.21e-07	27.517
ENSAPLP00000007786	pdb,3ceq,B,#1	180	299	8.75e-07	28.682
ENSSHAP00000013119	pdb,3ceq,B,#1	146	269	9.74e-07	26.357

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.051	0.062	0.887	0.194	0.316	0.49

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.355411954765751	0.148626817447496	0.0694668820678514	0.0274636510500808	0.00484652665589661	0.0274636510500808	0.0436187399030695	0.323101777059774

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.014947931 2.196867320 2.050640301 18.432360388 0.000369358 5.166426239 24.193069344 0.008148029 0.013226459 6.304382858 20.630100166 0.081497504 0.161375447 0.015804732 0.405306965 63.783719566 0.398258351 0.031847148 0.187018903 6.615541252 5.919897401 161.720449668 0.001541475 0.202364842 0.227731049 0.018533883 8.527258728 0.528053367 3.407727377 0.023734180 0.032667178 0.228365558 0.002159393 0.378149333 0.170043393 5.884372394 32.521328809 0.004289329 0.015425074 0.036284254 0.665449504 0.160012398 0.120994117 0.169326481 4.550107694 12.294545468 0.026420076 0.000002112 0.010930771 0.027143983 0.205978287 0.288705939 0.088897889 0.033992267 5.321886567 6.495726813 0.001003974 0.079921051 0.001427027 0.002066944 0.291061978 0.205238810 0.053703368 0.035656728 0.010710865 5.393597991 63.405592640 0.000005780 0.002505779 0.211196416 0.001336094 0.018215519 0.083828125 0.581746849 0.029144726 0.347901535 0.309470262 10.117890454 6.326729880 0.000000001 0.000815647 0.002464714 0.000002248 0.000002220 0.000000256 0.020903540 0.000000433 0.464847924 0.130765624 0.000000567 16.390402552 67.885941920 0.000000001 0.070714583 0.000841935 0.787138116 0.000102657 0.000265445 0.796111566 0.000000031 0.000007343 0.211220048 0.048320507 4.961438823 38.096972157 206.419804421 0.058477348 1.070470856 0.253577564 0.011794854 0.002069496 0.006757950 0.273094269 3.358183470 0.999029796 0.003569102 0.571489413 5.703183158 0.000034146 33.221037476 1220.910029181 0.005508154 0.110569240 2.595413697 0.069700139 1.586457091 0.113178142 3.517998512 0.137354613 0.144158760 0.000432688 0.001108657 0.000171212 0.000000215 0.000267935 262.056249480 15.487592536 0.000000001 0.000002979 0.007051736 0.035899268 0.166876348 5.387510350 0.016267309 0.000842257 3.101299090 0.071378646 0.157688024 29.646216505 0.540446745 0.001520245 0.014883705 0.001482954 0.358166205 0.000000001 0.000000001 0.000000001 0.000000007 0.044843740 0.804126691 0.006729637 1.390683794 0.000015358 1.506884618 0.000248831 9.896905511 0.057558640 0.000001584 0.000523102 0.000007183 0.005555008 3.499892335 0.000000001 0.000000001 0.000000001 0.000000001 0.000032927 0.046176883 0.703789988 0.000000001 0.000939733 0.684163682 0.015479555 3.025217785 0.983914753 3.029824459 16.348585440 0.000080903 0.000020755 89.781423744 0.000005387 0.133609000 0.082838500 0.069502600 0.086923500 0.081949900 0.089253100 0.075675700 0.096337500 0.081426200 0.079546900 0.061048200 0.030224700 0.018234100 0.004945270 0.001561970 0.000753307 0.000889005 0.001834600 0.003440620