Protein VARS2

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSONIP00000016427	pdb,1gax,A,#1	289	1263	0	36.382
ENSMPUP00000011551	pdb,1gax,B,#1	100	1016	0	38.028
ENSGACP00000012679	pdb,1ivs,A,#1	252	1218	0	35.942
ENSMPUP00000011551	pdb,1ivs,B,#1	100	1016	0	38.028
ENSNGAP00000009557	pdb,1gax,B,#1	295	1242	0	37.855
ENSMPUP00000011551	pdb,1gax,A,#1	100	1016	0	38.028
ENSDARP00000073707	pdb,1ivs,A,#1	85	916	0	37.56
ENSDARP00000073707	pdb,1ivs,B,#1	85	916	0	37.56
ENSDORP00000017778	pdb,1gax,A,#1	150	1112	0	37.746
ENSDARP00000073707	pdb,1gax,B,#1	85	916	0	37.56
YGR094W	pdb,1ivs,B,#1	146	1099	0	35.507

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.063	0.123	0.814	0.082	0.479	0.439

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.249197860962567	0.140463458110517	0.0192513368983957	0.0231729055258467	0.0185383244206774	0.00606060606060606	0.0035650623885918	0.539750445632799

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.000000194 0.000000194 2.172465192 0.000000423 0.000183495 5.671805067 0.000007572 0.236541354 0.020517883 5.215464577 0.000001353 0.017408695 0.107094474 0.224611502 0.027144402 0.000007776 0.086753948 0.225853732 0.770652267 5.653976968 8.891916343 0.000002644 0.023943455 0.065522067 0.079047684 0.168360783 11.215861710 0.024417503 0.000000446 0.025545084 0.006022957 0.083192682 0.091146047 0.267290783 0.194756855 9.707751499 0.000000483 0.019642678 0.042819886 0.004709385 0.196561859 0.129841692 0.184759705 0.015001198 8.162770640 0.000001173 0.000524229 0.017539970 0.027392843 0.066419620 0.442263702 0.053639801 0.268442085 0.010645139 6.060028083 0.000001459 0.003630252 0.014772085 0.000017524 0.018449509 0.243049798 0.191044463 0.094529364 0.169138141 0.013532984 6.002025928 0.000011611 0.013563740 0.000985482 0.021116609 0.116304368 0.033935261 0.246485529 0.193537196 0.119958068 0.181898718 0.065339277 7.578583007 0.000031619 0.000009506 0.010241724 0.001550544 0.003785532 0.292076407 0.156287072 0.006079086 0.081234175 0.181233664 0.049619540 0.002929518 14.898151958 0.000207427 0.073929648 0.584551106 0.020880836 0.000004435 0.012901732 0.050565141 0.001653564 0.000143223 0.000689598 0.123663002 0.004216704 0.060744039 61.211252298 0.064639846 0.000000001 0.229619646 0.493331320 1.009963216 0.001588955 0.321341138 0.000491242 0.003193998 0.000084106 0.054563067 0.001702331 2.458068427 0.402728093 72.538635843 0.072239069 0.362060131 0.000004227 0.494249753 0.002385663 0.000004694 0.000006833 0.000012857 0.609279191 0.000946019 0.000000121 0.980557935 0.014397672 0.005774613 10.283145635 148.928777338 0.017738250 0.000000001 0.000013444 0.000000049 0.000009898 1.562812033 0.001450001 0.009263440 0.149913612 0.032882058 0.037058310 0.000004192 0.000000124 0.000067716 16.928227716 1.036806703 877.047776374 0.005338751 0.000000001 0.825448276 0.000000143 0.000004359 0.000013292 0.000004498 1.323463965 0.199113375 0.000001166 1.094610338 0.568636167 0.000000310 0.499476812 0.000001649 0.000312353 0.014635092 418.478540074 0.021455595 0.000024448 0.109161402 0.029484459 0.963529825 0.262585705 1.338336780 1.383122901 2.324110255 5.111333911 1.551079836 1.018722880 2.998301058 39.046352715 5.138800485 125.408002460 2.511932675 424.477843676 191.820862514 0.000516737 0.145583000 0.089035500 0.072188200 0.108198000 0.066098800 0.082103400 0.060534100 0.072116200 0.079692700 0.083517300 0.070635500 0.045204600 0.017297800 0.003534930 0.001300850 0.000525448 0.000525561 0.000542600 0.000849602