Protein MFN1

Results of BLAST Screening for sufficient 3D structure homologs in Scratch-1D dataset

Protein ID	Structure	Start	End	E value	Bit score
ENSPEMP00000008846	pdb,1t3j,A,#1	674	735	1.07e-32	95.161
ENSLAFP00000007438	pdb,1t3j,A,#1	673	734	6.18e-32	91.935
ENSETEP00000012489	pdb,1t3j,A,#1	658	719	4.48e-31	90.323
ENSECAP00000016916	pdb,1t3j,A,#1	682	743	1.52e-30	88.71
ENSCAPP00000008720	pdb,1t3j,A,#1	574	635	1.55e-30	88.71
ENSCLAP00000023186	pdb,1t3j,A,#1	637	697	2.49e-30	90.164
ENSSARP00000012424	pdb,1t3j,A,#1	635	695	3.3e-30	90.164
ENSMLUP00000006954	pdb,1t3j,A,#1	698	759	6.38e-30	87.097
ENSCSAP00000009166	pdb,1t3j,A,#1	674	734	2.5e-29	90.164
ENSMEUP00000009808	pdb,1t3j,A,#1	636	697	2.37e-28	82.258
ENSANAP00000029527	pdb,1t3j,A,#1	674	734	2.42e-28	86.885

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.02	0.054	0.926	0.097	0.574	0.329

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.462335216572505	0.230696798493409	0.0178907721280603	0.00659133709981168	0.00282485875706215	0.00282485875706215	0.00282485875706215	0.274011299435028

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Predicted (by scratch-1d 1.1) residue solvent accessibilities coding: -5(unknown)=A, 0=R, 5=N, 10=D, 15=C, 20=E, 25=Q, 30=G, 35=H, 40=I, 45=L, 50=K, 55=M, 60=F, 65=P, 70=S, 75=T, 80=W, 85=Y, 90&95=V

Empirical model for relative rates of residue solvent accessibilities changes (in PAML format)

0.000611144 5.355349706 2.700496495 0.006019746 0.000001179 6.859371122 0.010082174 0.038898218 0.035645089 9.962943262 13.791805651 0.000480138 0.000879924 0.005749550 0.122532077 1.279719026 0.386988902 0.050116732 0.209739196 8.845392760 9.004356444 0.273614860 0.000000079 0.056156796 0.046351641 0.028782534 8.895718112 0.014104892 0.016475526 0.000034949 0.000046030 0.004074495 0.144589211 0.081501739 0.165753584 7.860617660 2.739251504 0.000001320 0.029894075 0.003528345 0.199106617 0.017624894 0.328226778 0.000117347 5.568186870 0.090370022 0.000000006 0.000622823 0.000000002 0.000001461 0.079144791 0.233294499 0.122010004 0.000011610 5.224575571 4.213586987 0.000000993 0.000001370 0.003938782 0.006159124 0.135480988 0.250681458 0.020546756 0.005395968 0.000000104 4.075769714 11.965744979 0.012536374 0.001195092 0.000000002 0.086018500 0.103057953 0.408511347 0.055191967 0.011403733 0.003100000 0.000024998 5.936846142 0.666469614 0.000457447 0.007903339 0.000000002 0.098540354 0.002588486 0.484022916 0.000082049 0.251299070 0.023031147 0.417863335 0.115365004 6.665088595 146.910869001 0.023223768 0.000000001 0.196096755 0.000024351 0.001298414 0.147320121 0.021388672 0.000000001 0.000000001 0.402246667 0.085647280 0.600020896 13.546135058 79.006962816 0.155591546 0.000000001 0.000000002 0.000000001 0.003943478 0.027373139 0.000000001 0.050031936 0.218368611 0.000000001 0.088211420 0.677658751 2.019440901 28.643113270 0.000169290 0.000000001 0.003401330 2.029858806 0.000000001 0.044314412 0.000000001 0.288405631 0.000000001 0.000000001 0.000000001 0.308876242 0.000000003 0.000000010 0.000014184 11.461125382 0.002820516 0.000000001 2.106692624 0.000000002 0.000000001 1.848501222 0.142285495 0.000164749 0.007405287 0.063392015 3.989406349 0.000000128 0.000000003 18.117812256 7.883047800 0.001147539 0.000000151 0.000262078 0.000000001 0.000000001 0.000000002 0.000000001 0.721235651 0.000384173 0.003441644 0.047287920 1.039506192 1.541962097 0.000000018 0.454719686 0.000000010 13.375768572 62.745695960 64.482816946 422.944898261 0.197229586 0.018305677 0.000000001 0.297325351 0.046208080 0.000147096 0.084996970 0.000000001 0.288096514 0.206907903 0.030985114 1.704045593 1.641570976 2.631404076 7.782150818 0.000000052 6.265653222 0.002265361 68.809050079 0.000373843 0.150656000 0.077356800 0.061851100 0.080704500 0.076989400 0.089440600 0.075708300 0.085484200 0.090221300 0.083635000 0.076134700 0.030628100 0.010112700 0.003714680 0.001934810 0.000662164 0.000758016 0.000687552 0.002945580