Protein ALAS1

Heterotachy (covarion) test results

Clades tested	Log Lh difference	p-value of difference
All clades	170.657769770201	0
Primates and Rodents clades	6.03373176520017	0.1966

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.393	0.309	0.298	0.475	0.283	0.242

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.552284263959391	0.0923857868020305	0.0050761421319797	0.00304568527918782	0.00101522842639594	0.00304568527918782	0.0050761421319797	0.338071065989848

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Empirical model for relative rates of amino acid substitutions (in PAML format)

0.053105607 0.203638613 0.072552770 0.723568361 0.294400988 4.164561334 0.786724810 3.769561588 0.632204875 1.765377819 0.108845203 3.990637551 0.195766498 0.077424928 0.000117032 1.235007397 0.268985827 0.416947140 7.722913963 0.001095290 3.403333828 2.091567678 1.655252167 1.152820003 1.341245410 1.237129834 0.282523274 1.817822371 0.342729121 3.445697961 3.031621377 2.026474053 2.147857951 4.707087007 0.204080507 0.400544155 0.307928511 0.173804744 0.650172280 0.000122447 0.004535207 0.040663545 0.113841019 0.000009663 0.000001913 0.251198370 0.394055858 0.020453182 0.022957446 0.268401805 0.635949186 0.059024976 0.070213279 0.264684693 1.635193921 0.135634449 5.697095714 2.548194267 0.269700818 0.005753218 2.907637700 1.866955190 0.556831537 0.050494707 0.080789902 0.163201412 0.123223793 0.665792272 0.000020563 0.004510091 0.545291366 0.568510994 0.216280955 0.000002784 0.000000920 3.177473159 4.652441818 0.636665442 0.007060827 0.073532952 0.250870823 0.219243211 1.845200501 0.000006406 0.083577439 0.142646486 0.019975461 1.345356687 2.374906820 0.061839126 0.008381081 2.069573526 0.317518004 0.014245920 0.139456163 1.031281654 1.587313074 0.189723793 0.001157267 1.431324619 0.000005662 1.812902211 0.223168380 0.005541953 0.042798879 3.553174843 1.319858616 6.025075578 0.736711208 2.073787464 0.615893393 0.482937609 2.788881496 0.550541897 0.503591970 0.510796523 0.275764878 0.010394938 1.145789456 2.265678163 5.450199286 0.243180292 3.323399020 0.118701858 0.122647173 0.512786789 0.050893693 0.537253484 0.111899706 2.024454451 0.300777579 1.651968701 2.207051458 0.773602163 1.412501078 5.336677499 0.000094460 5.530606811 2.575473664 0.000001432 0.000054884 0.000014634 0.000000783 0.000026734 0.000004448 0.000045899 0.054868660 0.000011273 3.797568727 0.000143260 0.000020639 0.000089230 0.000072872 0.471898028 0.000009711 0.669364347 0.195885904 1.398692129 0.262702666 0.184534656 0.000007870 8.253661145 0.251537832 0.260169741 0.000000337 0.594827311 9.612995150 0.004556760 0.227943900 0.040021206 5.119796401 3.219950750 0.180952350 0.018373799 0.219939170 0.304364536 0.191060102 0.383910304 0.364213604 0.000584626 11.724426164 2.484342409 0.024105090 3.388178720 1.204042396 0.243194712 0.368746333 1.206333311 0.000161011 0.267541993 0.086659400 0.061223300 0.035030100 0.043465200 0.013426400 0.055275800 0.065251700 0.057263100 0.031786500 0.039240300 0.073111500 0.070213800 0.031275800 0.032144300 0.054520100 0.096127600 0.059416000 0.002475450 0.016919400 0.075174000