Protein ALDH18A1

Heterotachy (covarion) test results

Clades tested	Log Lh difference	p-value of difference
All clades	292.764120665401	0
Primates and Rodents clades	54.5516222756005	4.033e-11

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.501	0.339	0.16	0.532	0.319	0.15

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.74328678839957	0.0934479054779807	0.0161117078410312	0.00644468313641246	0.00214822771213749	0.00214822771213749	0.00214822771213749	0.134264232008593

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Empirical model for relative rates of amino acid substitutions (in PAML format)

0.485396158 0.000268433 0.318381170 0.270859087 0.113589818 5.766442325 0.951565277 3.106403455 0.026604612 0.000000093 0.408092117 3.991411664 0.243095304 0.229330674 0.929583498 0.511737889 0.006133600 0.127184249 7.837207761 0.000000148 2.639636819 1.266083626 1.210599052 1.614054315 0.464066459 1.131314705 0.246528647 0.551260689 0.570426205 3.264516752 5.156653597 1.049133670 0.868985698 7.689476362 0.410534550 0.219227113 0.076569112 0.178939762 0.305190228 0.054219164 0.361389972 0.309868112 0.057585882 0.000000009 0.000758543 0.318963339 0.331378563 0.211217879 0.112392505 1.192852653 0.531042580 0.000000187 0.019710384 0.628972040 3.463003366 0.020600688 6.238332151 1.732122092 0.226210968 0.008316913 2.431531778 1.351703794 0.250221291 0.398937620 0.000001412 0.293173721 0.070365412 0.760134336 0.000004688 0.053064397 0.000014829 1.127158344 0.192966800 0.126208516 0.000028930 2.836173693 6.994239549 0.823752419 0.187885172 0.252485089 0.741299023 0.179507134 3.498600905 1.258719474 0.000058751 0.004225252 0.222816765 1.284243539 3.409473051 0.081223973 0.018907154 1.269940989 0.588742253 0.174754819 0.194492258 0.799242319 1.176479336 0.000008454 0.560710753 1.072620263 0.128092894 0.867640032 0.603450821 0.079497494 0.165911155 3.630726267 0.906157694 4.649645478 0.131759320 3.737615363 0.218566061 0.201316325 1.822387084 0.586074329 0.464444805 0.640583763 0.891777103 0.013807527 1.509854868 3.645613048 2.618845137 1.017702828 1.757715621 0.450780521 1.207444412 0.409971822 0.321196186 0.365734000 0.330893959 1.733581779 0.234479972 1.986046134 3.023930716 0.000118590 0.588624859 5.154981810 0.000000007 4.021199437 1.147962912 0.000175864 0.000000220 0.000000732 0.538573309 0.000000019 2.673257944 0.000000314 1.171480582 0.085943810 0.000000258 4.210223164 0.000000003 0.000002245 0.682114723 0.066490679 0.283851331 0.657034361 0.238829125 6.371697662 0.648745695 0.000000814 1.051215989 8.745903562 0.124178353 0.038480968 0.000001166 0.000004477 16.919428889 0.001326690 0.147580188 0.284275674 8.398815157 2.018224350 0.020942686 0.000000896 0.103513577 0.555550487 0.000029690 0.435478633 0.186495394 0.004388624 8.564341157 1.620686743 0.019691801 3.190259948 1.134024519 0.224205849 0.353404857 0.536241485 0.845541548 0.303314893 0.088661600 0.060058200 0.038869200 0.058851700 0.017975900 0.051104000 0.070818400 0.051854900 0.031551800 0.056055100 0.093551700 0.060298700 0.022769900 0.023785200 0.035560000 0.090655800 0.055549600 0.005526470 0.015780300 0.070721200