Protein ALDH1B1

Heterotachy (covarion) test results

Clades tested	Log Lh difference	p-value of difference
All clades	65.0414583310012	2.522e-13

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.388	0.376	0.235	0.423	0.372	0.205

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.888307155322862	0.0244328097731239	0.00349040139616056	0.0104712041884817	0	0.0191972076788831	0.0366492146596859	0.0174520069808028

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Empirical model for relative rates of amino acid substitutions (in PAML format)

0.000000003 0.043919157 0.000000004 1.168832519 0.000000001 5.420015239 1.523472438 10.577545461 0.000000003 0.000000002 0.738307545 6.947845832 0.140145439 0.143433649 0.000000009 1.144197604 0.058798044 0.000014439 3.926443450 0.000000006 2.074676138 1.670368354 0.966225914 0.375874667 3.177961898 2.269344031 0.154660587 0.764447965 0.000003454 13.130005495 4.335360650 0.450238027 4.893805711 13.013490421 0.000000001 0.931923081 0.000000001 0.000000001 0.694995248 0.000000002 0.000000006 0.000000002 0.000000001 0.000763556 0.000000004 0.000047633 0.562625438 0.000000003 0.000000002 0.000000103 0.827945511 0.000000001 0.000000001 1.126216566 1.168094065 0.000000001 7.372976880 2.322418672 0.000000002 0.000000006 2.150068309 3.456973252 0.059373683 0.000012020 0.000000002 0.000000001 0.179566957 0.328390110 0.000000003 0.000000002 0.838370886 0.000000026 0.000000001 0.326423043 2.820594841 2.105727826 6.013309184 0.000000002 0.000000001 0.167723989 0.000000003 0.000000002 0.977065756 0.000000002 0.000000001 0.000000001 0.000000004 0.001060567 3.107820487 0.000000002 0.000000004 2.697477291 0.960909924 0.000000003 0.000000002 0.506368480 1.204199119 0.141524638 0.000000001 3.402738549 0.000000002 4.157603974 0.000000002 0.000000004 0.000000635 2.763505918 1.926375988 15.131290940 0.132776644 9.093807981 0.016773281 0.388133867 4.657507594 0.265718795 1.777713128 1.370629061 0.598424966 0.000153101 3.188571331 3.353982319 4.680278119 0.267199204 1.277777329 0.000034585 0.000000149 0.000000003 0.004216647 0.152266438 0.000000016 1.697994178 0.000001405 0.911605766 4.403192708 0.000000002 1.513573935 5.049008570 0.000000001 9.088535148 0.000000003 0.000000002 5.876772411 0.000000002 0.000000001 0.667177856 0.000000004 0.000000003 1.414701447 0.000000002 0.000000035 2.108503438 0.000000002 0.000000003 0.000000002 0.000000001 0.000000001 0.459753868 0.286835549 4.182787401 0.432611589 0.000000001 0.000000001 4.770001021 0.000000005 0.471831109 0.000000002 0.000000033 3.735097873 0.060801066 0.523142408 0.000000002 0.000000007 4.029264303 0.000000001 0.058323439 0.300902500 0.686512372 0.000000002 0.000000001 0.060572568 0.000000004 11.011574592 2.790520297 0.000000002 7.653854708 1.077655902 0.051288453 0.000086272 0.166680109 0.266164369 0.029698193 0.073119800 0.067513300 0.037142700 0.055434900 0.017624300 0.045528600 0.070314400 0.074010400 0.023508800 0.054481400 0.085745300 0.064785900 0.023829300 0.047015100 0.050188100 0.036860900 0.058274800 0.013391800 0.034545200 0.066684900