Protein GPX4

Heterotachy (covarion) test results

Clades tested	Log Lh difference	p-value of difference
Primates and Rodents clades	377.442838142801	0

Alignment variation features

Conservative sites proportion	Intermediate sites proportion	Variable sites proportion	Conservative sites heterotachy weight	Intermediate sites heterotachy weight	Variable sites heterotachy weight
0.161	0.325	0.514	0.168	0.316	0.516

Site diversity ≤ 0.125	0.125 < Site diversity ≤ 0.25	0.25 < Site diversity ≤ 0.375	0.375 < Site diversity ≤ 0.5	0.5 < Site diversity ≤ 0.625	0.625 < Site diversity ≤ 0.75	0.75 < Site diversity ≤ 0.875	Site diversity > 0.875
0.145705521472393	0.134969325153374	0.0521472392638037	0.0230061349693252	0.0276073619631902	0.0107361963190184	0.00920245398773006	0.596625766871166

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Empirical model for relative rates of amino acid substitutions (in PAML format)

0.402376323 0.132358039 0.258616032 0.844564738 0.008413938 6.897475159 0.538258953 1.610314182 0.149145536 0.025681823 0.804433202 3.626309093 0.365463816 0.142703213 0.258521013 1.621522784 0.167976510 0.161039351 8.555488799 0.000994398 3.367517576 2.147002493 1.606618381 0.995253100 1.718390951 1.066648945 0.165956452 0.878350499 0.255970802 5.079710287 4.370949315 0.699965436 0.455362092 6.253454848 0.669744338 0.152737238 0.099464026 0.027853773 0.311351744 0.005175382 0.036282299 0.031613466 0.003305143 0.005359548 0.303388155 0.451656127 0.674119605 0.031534493 0.089105679 0.381939952 0.714054899 0.029057179 0.030182065 0.591325210 2.249547002 0.119628663 7.614446511 2.403814797 0.030268136 0.002891591 2.848882597 1.512267310 0.288966618 0.173823136 0.125319440 0.075437383 0.730349438 1.367655868 0.126254592 0.000320028 0.221186478 0.274065424 0.096313142 0.140099530 0.072246037 3.485628134 4.691531282 0.786383624 0.025556752 0.071357933 0.021121655 0.074946125 0.717045964 0.125282857 0.000878208 0.004819055 0.025997944 0.629847783 2.814733234 0.005282753 0.332501098 1.289613703 1.227788979 0.145357950 0.045212451 0.148379189 1.304957368 0.141207529 0.070036137 0.746809789 0.129940256 1.084357104 0.097636239 0.015823778 0.040575591 5.027022730 0.954605070 4.310392861 0.691723480 3.786343341 0.569052388 0.305340168 2.429060822 0.905294582 0.381115476 0.513151976 0.345799284 0.055320179 1.271406599 2.956910771 5.620106241 0.376355094 1.897870374 0.484011348 0.907014409 0.750615947 0.081814864 0.110810794 0.326399893 3.040800273 0.325149642 1.156367110 4.523877827 0.095827068 1.582571268 5.937235059 0.686505981 1.921797005 0.236550269 0.144997877 3.872008822 0.655161016 0.049033057 0.936135552 0.000485133 0.007966284 0.665638312 0.000020000 0.228896340 0.237143998 0.206894350 0.533978148 0.020775290 0.010775023 0.031450328 0.452840905 0.317836075 1.470992768 0.049272063 0.078811356 0.004816345 10.443673970 0.028868511 0.041815464 0.000030098 0.111489776 5.898070696 0.160868645 0.752283718 0.144618225 1.813663524 3.707382647 0.044325144 0.087108861 0.004210426 0.534880057 0.234742672 0.223092060 0.254826527 0.138513007 12.337775135 1.639301999 0.089683942 4.137511542 0.557147920 0.079463282 0.041048421 1.118635666 0.117529709 0.118429313 0.069182500 0.051085000 0.046303900 0.043108700 0.020313900 0.045986100 0.063013000 0.063839900 0.020131900 0.042715400 0.092704700 0.077571300 0.022309400 0.058124600 0.054807200 0.066996000 0.049826500 0.010426300 0.037146800 0.064407000