Natural logarithm of Amino acid over Solvent accessabilities tree branch lengths ratios

Propertites of Heterotachy Phylogeny of ACAA2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node Median of branch length from Mean of logarithmic ratios Median of logarithmic ratios Q1 or 25% quantile of logarithmic ratios Q3 or 75% quantile of logarithmic ratios Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches

Amino acids - based tree Residue solvent accessabilities - based tree Difference, U-test Cliff's delta Normalized p-value, U-test (Holm correction for multiple tests)

N17 2e-06 0.019286 8.98282 9.25433 8.21067 9.83357 Greater 0.94909 4.136e-14

N95 0.033211 2.010045 4.37038 4.25138 3.94229 4.67250 Greater 0.86345 4.136e-14

N18 3e-06 0.002116 6.70774 6.67540 6.51619 8.78666 Greater 0.84898 4.136e-14

N19 3e-06 0.046067 5.68957 6.35389 1.99012 10.02659 Greater 0.81734 4.136e-14

N35 0.004173 0.065212 5.12793 2.78981 1.74050 10.19787 Greater 0.80248 4.136e-14

N176 0.064774 0.439214 2.75491 2.92741 1.94912 3.56500 Greater 0.78570 4.136e-14

N165 0.286131 2.343024 2.35272 2.32936 2.13080 2.55197 Greater 0.77987 4.136e-14

N31 0.024273 0.251558 2.26838 2.12734 1.63716 2.79803 Greater 0.75280 4.136e-14

N29 0.003792 0.018746 4.37488 2.91527 1.58158 9.50034 Greater 0.71761 4.136e-14

N15 3e-06 0.014183 3.86014 2.02713 0.64059 8.71446 Greater 0.66284 4.136e-14

N8 0.005265 0.03399 1.57729 1.72284 1.19808 2.17571 Greater 0.66003 4.136e-14

N6 0.013757 0.060295 1.55759 1.60406 1.08230 2.17573 Greater 0.65605 4.136e-14

N23 0.0071 0.017326 4.04826 2.54522 0.53573 9.25249 Greater 0.64535 4.136e-14

N139 2e-06 1e-06 3.69481 5.73657 0.00000 8.12459 Greater 0.61631 4.136e-14

N181 0.012658 0.05989 1.33066 1.46289 0.78715 2.06470 Greater 0.60526 4.136e-14

N120 1e-06 1e-06 1.96665 0.69315 0.69315 5.09987 Greater 0.59504 4.136e-14

N187 0.008142 0.039923 1.30260 1.14583 0.42499 1.81915 Greater 0.59032 4.136e-14

N121 2e-06 9.2e-05 4.22279 6.82907 -0.40547 8.71380 Greater 0.58364 4.136e-14

N38 2e-06 0.009119 2.77200 0.83906 0.00000 8.44128 Greater 0.53343 4.136e-14

N11 0.010671 0.031963 0.88793 0.89712 0.30041 1.63296 Greater 0.52501 4.136e-14

N25 1e-06 1e-06 2.93700 0.00000 0.00000 9.62152 Greater 0.51982 4.136e-14

N182 0.030715 0.051781 0.75972 0.70682 0.25025 1.18718 Greater 0.51509 4.136e-14

N1 0.006129 0.006564 1.33541 0.86785 0.00000 1.68042 Greater 0.50779 4.136e-14

N16 0.003479 0.009375 2.24195 1.26830 -1.27728 6.11810 Greater 0.49693 4.136e-14

N42 3e-06 3e-06 2.09581 0.40547 0.00000 8.64212 Greater 0.49271 4.136e-14

N183 0.013824 0.021875 0.72526 0.72974 0.06890 1.36454 Greater 0.48996 4.136e-14

N189 0.03744 0.070039 0.65560 0.68153 0.16127 1.17801 Greater 0.48806 4.136e-14

N104 0.356594 0.747484 0.73805 0.96564 -0.38348 1.62971 Greater 0.47898 4.136e-14

N39 0.022604 0.064707 0.82307 0.88607 -0.05120 1.70790 Greater 0.47636 4.136e-14

N32 0.020685 0.022792 0.62572 0.63304 0.03016 1.24493 Greater 0.47443 4.136e-14

N190 0.02003 0.016777 1.80599 0.53822 -0.55450 2.17824 Greater 0.45684 4.136e-14

N168 0.064131 0.074624 0.50071 0.29302 -0.40085 1.16901 Greater 0.40525 4.136e-14

N33 0.026228 0.037907 0.27461 0.46759 -0.15690 0.97550 Greater 0.40445 4.136e-14

N2 0.014766 0.01965 0.35627 0.49831 -0.40964 1.07467 Greater 0.40181 4.136e-14

N12 0.00905 0.015351 0.31479 0.67021 -0.20457 1.52397 Greater 0.39800 4.136e-14

N178 0.014231 0.015303 0.31302 0.32913 -0.29546 0.96332 Greater 0.39126 4.136e-14

N41 2e-06 0.002689 1.67945 0.00000 -0.90499 7.39111 Greater 0.38365 4.136e-14

N9 0.050137 0.057972 0.20129 0.21589 -0.09064 0.50803 Greater 0.38206 4.136e-14

N179 0.010709 0.010961 0.21596 0.23893 -0.16698 0.81106 Greater 0.37948 4.136e-14

N30 3e-06 3e-06 0.16608 0.00000 0.00000 0.40547 Greater 0.37857 4.136e-14

N93 0.050884 0.585985 -0.19276 1.84918 -0.96630 2.72676 Greater 0.37149 4.136e-14

N143 0.003743 0.006239 1.05527 0.40547 -1.59065 6.13773 Greater 0.36705 4.136e-14

N21 0.004246 0.011983 0.05778 0.57557 -1.39047 1.74231 Greater 0.35971 4.136e-14

N36 0.066624 0.058019 0.11842 0.13851 -0.17485 0.44357 Greater 0.35508 4.136e-14

N71 2e-06 3e-06 0.09978 0.00000 0.00000 0.40547 Greater 0.35246 4.136e-14

N13 3e-06 2e-06 0.08994 0.00000 0.00000 0.40547 Greater 0.34905 4.136e-14

N27 0.020922 0.021035 0.15254 0.13921 -0.61536 0.81093 Greater 0.34580 4.136e-14

N20 0.007067 0.003836 0.64765 0.21330 -1.11953 1.25589 Greater 0.33907 4.136e-14

N22 0.038456 0.030599 -0.01210 -0.00082 -0.45558 0.40647 Greater 0.30638 4.136e-14

N161 0.015053 0.002569 -0.64079 0.41462 -2.24072 1.98482 Greater 0.29827 4.136e-14

N61 3e-06 2e-06 -0.07358 0.00000 -0.40547 0.00000 Greater 0.28508 4.136e-14

N146 0.00257 2e-06 -0.05101 0.00000 -6.80239 3.12282 Greater 0.28321 4.136e-14

N7 0.023897 0.012674 -0.05071 -0.12942 -0.70282 0.43465 Greater 0.28174 4.136e-14

N184 0.074995 0.046513 -0.16285 -0.10427 -0.50418 0.27378 Greater 0.26786 4.136e-14

N133 0.004101 0.000327 -0.59193 0.00000 -7.14572 2.19623 Greater 0.26545 4.136e-14

N14 3e-06 3e-06 -0.73921 0.00000 -7.61653 1.03649 Greater 0.25952 4.136e-14

N142 2e-06 2e-06 0.01314 0.00000 -7.30653 4.75728 Greater 0.25480 4.136e-14

N160 0.012253 3e-06 -0.86518 0.00000 -7.55564 2.79127 Greater 0.24437 4.136e-14

N102 0.071293 0.636893 -1.46030 1.76002 -9.63255 2.48984 Greater 0.23380 4.136e-14

N172 0.072866 0.041238 -0.32502 -0.28492 -1.02969 0.33718 Greater 0.22406 4.136e-14

N185 0.114975 0.069712 -0.46759 -0.32819 -0.79693 0.10159 Greater 0.19480 4.136e-14

N88 0.018685 0.019546 -0.39161 -0.44168 -0.76305 0.02313 Greater 0.18829 4.136e-14

N149 2e-06 3e-06 -1.00103 0.00000 -7.97178 0.98735 Greater 0.18615 4.136e-14

N34 0.004435 0.000774 -1.21802 -0.22382 -2.39870 0.55134 Greater 0.18419 4.136e-14

N65 2e-06 2e-06 -1.34879 0.00000 -7.63603 0.40547 Greater 0.18234 4.136e-14

N180 0.15609 0.07084 -0.41720 -0.46201 -0.83908 0.00399 Greater 0.18155 4.136e-14

N28 0.082845 0.052628 -0.44644 -0.41477 -0.82175 0.00349 Greater 0.17747 4.136e-14

N24 1e-06 1e-06 -1.51151 0.00000 -8.35397 0.00000 Greater 0.15610 4.136e-14

N97 0.092636 0.062401 -0.56909 -0.72544 -1.17064 0.01692 Greater 0.14881 1.485e-13

N175 0.24611 0.128328 -0.51985 -0.46227 -0.79325 -0.18386 Greater 0.14257 4.136e-14

N37 0.010356 0.010631 -1.75618 -0.31436 -7.61997 0.44882 Greater 0.14084 4.136e-14

N144 0.011287 0.000545 -2.53301 -0.23962 -8.56713 2.03933 Greater 0.13921 4.136e-14

N171 0.16796 0.077914 -0.57177 -0.65262 -1.09989 -0.15498 Greater 0.13710 4.136e-14

N173 0.136601 0.075007 -0.75705 -0.72971 -1.40554 -0.00390 Greater 0.12871 6.293e-13

N82 0.003554 2e-06 -2.28140 -0.09182 -7.22475 0.00000 Greater 0.12673 1.34028e-12

N119 0.004118 0.020783 -1.91547 -0.69315 -7.77591 1.07651 Greater 0.12384 8.622e-10

N94 0.020169 2e-06 -2.78261 0.00000 -8.56076 0.98052 Greater 0.11242 2.19604e-10

N134 0.008437 0.000433 -2.31008 -1.65894 -7.76811 1.45873 Greater 0.10286 1.42361e-08

N89 0.137595 0.111301 -1.08680 -0.88008 -1.91323 0.02140 Greater 0.09443 2.7222e-06

N5 0.178489 0.129838 -0.79333 -0.62217 -1.17709 -0.26008 Greater 0.09365 2.4678e-07

N174 0.132184 0.071384 -0.93514 -0.74700 -1.20449 -0.26015 Greater 0.08605 3.7425e-05

N111 0.031146 0.008108 -1.11789 -0.88377 -1.68814 -0.16551 Greater 0.08243 0.0062046

N4 0.006261 0.001421 -1.06246 -1.79561 -2.66292 0.00000 Greater 0.07399 0.000100372

N43 0.197816 0.098408 -0.79603 -0.72042 -1.12396 -0.40289 Greater 0.06913 0.00060249

N26 0.098031 0.053979 -0.92209 -1.06107 -1.59160 -0.24483 Greater 0.06835 0.0011828

N166 0.30652 0.121868 -0.88055 -0.84182 -1.25305 -0.41661 Greater 0.06407 0.0011828

N105 0.254159 0.076276 -0.87620 -0.86800 -1.18747 -0.46410 Greater 0.05116 0.026955

N170 0.395391 0.155732 -0.87624 -0.93248 -1.19637 -0.59746 Greater 0.04405 0.052806

N98 0.005558 3e-06 -3.53441 -5.81711 -7.94236 0.40547 Greater 0.04299 0.0582

N177 0.104192 0.02762 -1.14195 -1.15295 -1.63874 -0.50273 Greater 0.03111 0.33504

N188 0.021998 0.021806 -3.17502 -0.29746 -9.10365 0.52247 Greater 0.02241 0.62349

N109 0.005816 3e-06 -3.01908 -1.74894 -8.08687 0.49723 Greater 0.01597 0.966

N10 0.036158 0.010933 -1.59993 -1.02833 -1.47288 -0.48671 Greater 0.01259 0.966

N73 0.003607 2e-06 -3.95466 -7.23129 -7.61727 0.00000 Lesser -0.00286 0.966

N84 2e-06 1e-06 -2.87040 -0.69315 -8.69492 0.00000 Lesser -0.00405 0.966

N46 3e-06 3e-06 -4.15755 -7.30765 -8.11582 0.00000 Lesser -0.02230 0.62349

N127 0.016638 0.000277 -3.66418 -4.50503 -8.64816 0.40547 Lesser -0.02440 0.739

N157 0.012716 0.000181 -3.98720 -7.45732 -8.61114 0.40547 Lesser -0.03843 0.1046

N3 0.00938 0.002557 -2.23719 -1.63488 -2.36106 -0.76724 Lesser -0.04075 0.12114

N103 0.034293 0.030173 -3.63671 -0.42893 -9.38673 0.49137 Lesser -0.04087 0.077242

N54 0.00805 0.018934 -4.69275 -7.52023 -8.40485 0.54228 Lesser -0.04775 0.028756

N63 0.044934 0.259793 -4.07883 -7.75598 -9.69505 1.76150 Lesser -0.04993 0.021552

N66 0.027064 0.064954 -3.59178 -1.35539 -9.24818 0.47183 Lesser -0.05412 0.0097393

N155 0.00893 2e-06 -4.17719 -7.48885 -8.86007 0.40547 Lesser -0.07381 0.000100936

N68 0.034355 0.070009 -3.71934 -0.85290 -9.46234 0.44920 Lesser -0.07548 6.8832e-05

N140 0.033746 0.00161 -3.07507 -2.40357 -4.84156 -1.11731 Lesser -0.10113 1.87068e-08

N141 0.044252 0.121471 -3.59135 -2.73131 -9.65899 1.45885 Lesser -0.11406 1.14816e-10

N150 0.018297 3e-06 -4.27703 -3.77744 -9.00549 -0.25710 Lesser -0.13008 1.00159e-13

N186 0.050899 0.033144 -3.85147 -1.01713 -9.60602 0.00000 Lesser -0.13433 4.136e-14

N169 0.461063 0.071302 -2.06785 -1.97784 -2.39966 -1.62037 Lesser -0.13872 4.136e-14

N118 0.02054 0.001141 -4.37706 -4.42333 -8.89994 -0.40279 Lesser -0.15178 1.66089e-11

N64 0.016086 3e-06 -5.20878 -8.06380 -9.28508 0.40547 Lesser -0.15793 4.136e-14

N151 0.059763 3e-06 -4.37309 -2.54824 -9.99660 0.76872 Lesser -0.16007 4.136e-14

N101 0.02161 2e-06 -5.09721 -8.48229 -9.30068 0.10715 Lesser -0.17313 4.136e-14

N67 0.013873 2e-06 -5.12774 -8.33519 -9.19150 -0.15416 Lesser -0.17511 4.136e-14

N136 0.016453 0.000576 -3.99916 -3.65416 -9.14340 -0.60257 Lesser -0.17855 4.136e-14

N47 0.010304 2e-06 -5.78679 -8.12316 -8.63917 -0.47191 Lesser -0.20639 4.136e-14

N153 0.028465 0.001292 -5.02294 -8.76390 -9.52501 0.24102 Lesser -0.20683 4.136e-14

N69 0.021707 0.008965 -5.30511 -8.61275 -9.23468 -0.22845 Lesser -0.21288 4.136e-14

N167 0.143801 0.145708 -3.77429 -1.90517 -5.64290 -0.76581 Lesser -0.21300 4.136e-14

N99 0.008937 3e-06 -6.33322 -7.99587 -8.43069 -7.14441 Lesser -0.21407 4.136e-14

N130 0.01465 0.000259 -4.94453 -7.87601 -9.08772 -1.70041 Lesser -0.21802 4.136e-14

N76 0.034926 0.1316 -4.94815 -9.02588 -9.99263 0.47258 Lesser -0.22012 4.136e-14

N78 0.006392 2e-06 -6.13411 -8.15498 -8.80380 -0.40547 Lesser -0.23923 4.136e-14

N117 0.039571 0.000655 -4.82934 -2.73172 -9.85003 -0.10986 Lesser -0.24623 4.136e-14

N137 0.030435 0.000502 -4.29759 -3.59080 -9.41626 -1.07497 Lesser -0.25038 4.136e-14

N145 0.030689 2e-06 -5.01313 -8.38389 -9.66173 -0.55927 Lesser -0.26009 4.136e-14

N87 0.027234 6e-06 -4.54845 -2.14116 -9.54175 -1.02133 Lesser -0.26290 4.136e-14

N114 0.010438 3e-06 -6.05251 -6.60530 -8.53083 -5.26786 Lesser -0.26372 4.136e-14

N75 0.016619 2e-06 -5.98060 -8.51409 -9.35379 -0.38480 Lesser -0.26448 4.136e-14

N152 0.028493 0.001188 -5.72471 -8.70168 -9.46014 -0.58823 Lesser -0.27103 4.136e-14

N148 0.032784 0.273336 -4.94642 -3.92823 -9.46223 -1.42930 Lesser -0.27153 4.136e-14

N138 0.02433 0.563424 -4.72588 -3.89415 -9.14505 -1.52606 Lesser -0.27333 4.136e-14

N124 0.01229 0.000614 -6.34417 -8.37078 -9.00778 -2.62311 Lesser -0.30407 4.136e-14

N106 0.015119 2e-06 -5.90432 -8.10410 -8.80192 -2.33583 Lesser -0.34033 4.136e-14

N91 0.063102 0.017846 -5.48053 -9.00356 -10.12128 -0.52941 Lesser -0.34742 4.136e-14

N163 0.060446 2e-06 -5.58238 -7.50604 -10.06369 -1.03269 Lesser -0.37972 4.136e-14

N112 0.031219 3e-06 -6.19636 -8.32966 -9.51242 -2.45556 Lesser -0.38338 4.136e-14

N147 0.046617 0.000756 -5.75028 -4.91442 -9.86237 -2.05183 Lesser -0.40589 4.136e-14

N129 0.035443 0.000454 -6.07074 -8.75216 -9.60637 -2.67124 Lesser -0.40993 4.136e-14

N107 0.009704 2e-06 -7.92301 -8.42332 -8.77207 -7.79996 Lesser -0.42112 4.136e-14

N86 0.122371 0.002931 -5.80663 -9.29152 -10.76854 -0.86955 Lesser -0.43962 4.136e-14

N159 0.042881 2e-06 -6.45308 -9.22901 -10.02407 -1.38570 Lesser -0.44141 4.136e-14

N132 0.029479 0.002669 -6.44265 -8.75242 -9.70519 -2.94752 Lesser -0.44427 4.136e-14

N57 0.013629 2e-06 -8.46848 -8.49352 -9.12003 -7.67136 Lesser -0.46609 4.136e-14

N81 0.037774 0.018884 -7.10267 -9.40055 -9.91575 -1.23507 Lesser -0.47133 4.136e-14

N158 0.076008 0.003097 -6.66403 -10.12286 -10.55635 -0.83424 Lesser -0.48155 4.136e-14

N90 0.01176 2e-06 -8.63008 -8.79981 -9.02305 -8.42585 Lesser -0.48915 4.136e-14

N62 0.01821 2e-06 -8.62667 -8.63076 -9.04375 -8.36116 Lesser -0.48925 4.136e-14

N108 0.008057 2e-06 -8.67523 -8.81552 -9.16649 -8.31544 Lesser -0.49153 4.136e-14

N80 0.013808 2e-06 -8.62144 -8.77648 -9.13465 -8.17745 Lesser -0.49228 4.136e-14

N156 0.13132 3e-06 -6.14431 -4.15063 -10.86374 -1.62521 Lesser -0.49515 4.136e-14

N135 0.065082 0.004491 -6.55705 -9.21407 -10.45152 -2.48670 Lesser -0.50161 4.136e-14

N83 0.069077 3e-06 -6.55939 -10.13519 -10.56472 -0.94031 Lesser -0.50586 4.136e-14

N110 0.011953 2e-06 -8.62635 -8.91939 -9.33079 -8.36019 Lesser -0.51376 4.136e-14

N48 0.037271 2e-06 -7.24935 -9.53777 -9.93792 -2.84574 Lesser -0.51437 4.136e-14

N92 0.047093 2e-06 -7.15020 -9.81949 -10.20068 -0.95456 Lesser -0.51565 4.136e-14

N49 0.013669 3e-06 -8.63449 -8.82237 -9.38265 -8.07745 Lesser -0.51594 4.136e-14

N122 0.022311 0.00211 -7.87675 -8.98377 -9.52186 -5.33076 Lesser -0.51846 4.136e-14

N96 0.014474 2e-06 -8.79616 -8.82203 -9.16178 -8.48694 Lesser -0.51891 4.136e-14

N59 0.016899 2e-06 -8.75658 -8.89227 -9.34906 -8.34640 Lesser -0.52496 4.136e-14

N116 0.042083 0.001207 -7.46406 -9.63243 -10.07580 -4.76087 Lesser -0.53616 4.136e-14

N55 0.020196 3e-06 -8.92070 -8.99119 -9.23363 -8.68941 Lesser -0.54710 4.136e-14

N52 0.01674 2e-06 -8.93432 -9.00159 -9.31857 -8.68688 Lesser -0.55444 4.136e-14

N77 0.020056 2e-06 -8.93213 -9.00549 -9.44553 -8.46076 Lesser -0.56070 4.136e-14

N154 0.078493 0.002518 -7.41057 -10.12169 -10.47595 -1.94504 Lesser -0.57040 4.136e-14

N125 0.039165 0.001126 -7.78359 -9.66789 -10.09297 -5.99159 Lesser -0.57146 4.136e-14

N128 0.06205 0.023638 -7.29335 -9.88793 -10.35366 -2.93607 Lesser -0.57591 4.136e-14

N162 0.225274 0.015568 -6.96962 -10.88948 -11.44128 -2.04051 Lesser -0.57870 4.136e-14

N56 0.019663 2e-06 -9.10098 -9.21619 -9.47999 -8.81096 Lesser -0.59771 4.136e-14

N45 0.029571 2e-06 -9.13669 -9.17522 -9.37684 -8.89114 Lesser -0.59844 4.136e-14

N74 0.017703 3e-06 -9.12314 -9.20256 -9.58507 -8.78360 Lesser -0.60529 4.136e-14

N126 0.023619 0.001918 -9.09627 -9.28489 -9.62069 -8.86517 Lesser -0.61625 4.136e-14

N123 0.025882 0.000824 -9.13561 -9.22326 -9.79518 -8.55353 Lesser -0.61845 4.136e-14

N50 0.026528 3e-06 -9.15834 -9.26927 -9.70361 -8.69506 Lesser -0.62128 4.136e-14

N53 0.025448 2e-06 -9.21192 -9.30070 -9.59107 -8.95553 Lesser -0.62657 4.136e-14

N58 0.02822 2e-06 -9.25894 -9.49077 -9.83478 -8.75105 Lesser -0.64886 4.136e-14

N131 0.03432 0.001566 -9.06904 -9.49597 -9.90391 -8.95953 Lesser -0.66324 4.136e-14

N164 0.05022 3e-06 -8.09964 -9.83092 -10.24605 -3.62901 Lesser -0.67022 4.136e-14

N79 0.024079 2e-06 -9.46520 -9.52486 -9.93295 -9.12184 Lesser -0.69325 4.136e-14

N70 0.032945 2e-06 -9.49100 -9.55191 -9.80893 -9.21231 Lesser -0.70116 4.136e-14

N44 0.031917 2e-06 -9.60579 -9.73661 -10.03208 -9.34248 Lesser -0.73558 4.136e-14

N60 0.033878 2e-06 -9.71353 -9.78583 -9.97753 -9.46459 Lesser -0.76175 4.136e-14

N100 0.053706 2e-06 -9.87564 -9.94064 -10.22304 -9.59875 Lesser -0.80161 4.136e-14

N115 0.048534 2e-06 -10.02749 -10.15191 -10.49284 -9.58854 Lesser -0.82858 4.136e-14

N51 0.074332 3e-06 -10.24814 -10.30226 -10.54354 -9.99305 Lesser -0.88253 4.136e-14

N85 0.078312 3e-06 -10.26662 -10.28498 -10.53767 -10.02911 Lesser -0.88698 4.136e-14

N113 0.063364 3e-06 -10.38567 -10.41166 -10.64911 -10.14207 Lesser -0.91296 4.136e-14

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
Inner branch by (daughter) node	Amino acids - based tree	Residue solvent accessabilities - based tree	Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N17	2e-06	0.019286	8.98282	9.25433	8.21067	9.83357	Greater	0.94909	4.136e-14
N95	0.033211	2.010045	4.37038	4.25138	3.94229	4.67250	Greater	0.86345	4.136e-14
N18	3e-06	0.002116	6.70774	6.67540	6.51619	8.78666	Greater	0.84898	4.136e-14
N19	3e-06	0.046067	5.68957	6.35389	1.99012	10.02659	Greater	0.81734	4.136e-14
N35	0.004173	0.065212	5.12793	2.78981	1.74050	10.19787	Greater	0.80248	4.136e-14
N176	0.064774	0.439214	2.75491	2.92741	1.94912	3.56500	Greater	0.78570	4.136e-14
N165	0.286131	2.343024	2.35272	2.32936	2.13080	2.55197	Greater	0.77987	4.136e-14
N31	0.024273	0.251558	2.26838	2.12734	1.63716	2.79803	Greater	0.75280	4.136e-14
N29	0.003792	0.018746	4.37488	2.91527	1.58158	9.50034	Greater	0.71761	4.136e-14
N15	3e-06	0.014183	3.86014	2.02713	0.64059	8.71446	Greater	0.66284	4.136e-14
N8	0.005265	0.03399	1.57729	1.72284	1.19808	2.17571	Greater	0.66003	4.136e-14
N6	0.013757	0.060295	1.55759	1.60406	1.08230	2.17573	Greater	0.65605	4.136e-14
N23	0.0071	0.017326	4.04826	2.54522	0.53573	9.25249	Greater	0.64535	4.136e-14
N139	2e-06	1e-06	3.69481	5.73657	0.00000	8.12459	Greater	0.61631	4.136e-14
N181	0.012658	0.05989	1.33066	1.46289	0.78715	2.06470	Greater	0.60526	4.136e-14
N120	1e-06	1e-06	1.96665	0.69315	0.69315	5.09987	Greater	0.59504	4.136e-14
N187	0.008142	0.039923	1.30260	1.14583	0.42499	1.81915	Greater	0.59032	4.136e-14
N121	2e-06	9.2e-05	4.22279	6.82907	-0.40547	8.71380	Greater	0.58364	4.136e-14
N38	2e-06	0.009119	2.77200	0.83906	0.00000	8.44128	Greater	0.53343	4.136e-14
N11	0.010671	0.031963	0.88793	0.89712	0.30041	1.63296	Greater	0.52501	4.136e-14
N25	1e-06	1e-06	2.93700	0.00000	0.00000	9.62152	Greater	0.51982	4.136e-14
N182	0.030715	0.051781	0.75972	0.70682	0.25025	1.18718	Greater	0.51509	4.136e-14
N1	0.006129	0.006564	1.33541	0.86785	0.00000	1.68042	Greater	0.50779	4.136e-14
N16	0.003479	0.009375	2.24195	1.26830	-1.27728	6.11810	Greater	0.49693	4.136e-14
N42	3e-06	3e-06	2.09581	0.40547	0.00000	8.64212	Greater	0.49271	4.136e-14
N183	0.013824	0.021875	0.72526	0.72974	0.06890	1.36454	Greater	0.48996	4.136e-14
N189	0.03744	0.070039	0.65560	0.68153	0.16127	1.17801	Greater	0.48806	4.136e-14
N104	0.356594	0.747484	0.73805	0.96564	-0.38348	1.62971	Greater	0.47898	4.136e-14
N39	0.022604	0.064707	0.82307	0.88607	-0.05120	1.70790	Greater	0.47636	4.136e-14
N32	0.020685	0.022792	0.62572	0.63304	0.03016	1.24493	Greater	0.47443	4.136e-14
N190	0.02003	0.016777	1.80599	0.53822	-0.55450	2.17824	Greater	0.45684	4.136e-14
N168	0.064131	0.074624	0.50071	0.29302	-0.40085	1.16901	Greater	0.40525	4.136e-14
N33	0.026228	0.037907	0.27461	0.46759	-0.15690	0.97550	Greater	0.40445	4.136e-14
N2	0.014766	0.01965	0.35627	0.49831	-0.40964	1.07467	Greater	0.40181	4.136e-14
N12	0.00905	0.015351	0.31479	0.67021	-0.20457	1.52397	Greater	0.39800	4.136e-14
N178	0.014231	0.015303	0.31302	0.32913	-0.29546	0.96332	Greater	0.39126	4.136e-14
N41	2e-06	0.002689	1.67945	0.00000	-0.90499	7.39111	Greater	0.38365	4.136e-14
N9	0.050137	0.057972	0.20129	0.21589	-0.09064	0.50803	Greater	0.38206	4.136e-14
N179	0.010709	0.010961	0.21596	0.23893	-0.16698	0.81106	Greater	0.37948	4.136e-14
N30	3e-06	3e-06	0.16608	0.00000	0.00000	0.40547	Greater	0.37857	4.136e-14
N93	0.050884	0.585985	-0.19276	1.84918	-0.96630	2.72676	Greater	0.37149	4.136e-14
N143	0.003743	0.006239	1.05527	0.40547	-1.59065	6.13773	Greater	0.36705	4.136e-14
N21	0.004246	0.011983	0.05778	0.57557	-1.39047	1.74231	Greater	0.35971	4.136e-14
N36	0.066624	0.058019	0.11842	0.13851	-0.17485	0.44357	Greater	0.35508	4.136e-14
N71	2e-06	3e-06	0.09978	0.00000	0.00000	0.40547	Greater	0.35246	4.136e-14
N13	3e-06	2e-06	0.08994	0.00000	0.00000	0.40547	Greater	0.34905	4.136e-14
N27	0.020922	0.021035	0.15254	0.13921	-0.61536	0.81093	Greater	0.34580	4.136e-14
N20	0.007067	0.003836	0.64765	0.21330	-1.11953	1.25589	Greater	0.33907	4.136e-14
N22	0.038456	0.030599	-0.01210	-0.00082	-0.45558	0.40647	Greater	0.30638	4.136e-14
N161	0.015053	0.002569	-0.64079	0.41462	-2.24072	1.98482	Greater	0.29827	4.136e-14
N61	3e-06	2e-06	-0.07358	0.00000	-0.40547	0.00000	Greater	0.28508	4.136e-14
N146	0.00257	2e-06	-0.05101	0.00000	-6.80239	3.12282	Greater	0.28321	4.136e-14
N7	0.023897	0.012674	-0.05071	-0.12942	-0.70282	0.43465	Greater	0.28174	4.136e-14
N184	0.074995	0.046513	-0.16285	-0.10427	-0.50418	0.27378	Greater	0.26786	4.136e-14
N133	0.004101	0.000327	-0.59193	0.00000	-7.14572	2.19623	Greater	0.26545	4.136e-14
N14	3e-06	3e-06	-0.73921	0.00000	-7.61653	1.03649	Greater	0.25952	4.136e-14
N142	2e-06	2e-06	0.01314	0.00000	-7.30653	4.75728	Greater	0.25480	4.136e-14
N160	0.012253	3e-06	-0.86518	0.00000	-7.55564	2.79127	Greater	0.24437	4.136e-14
N102	0.071293	0.636893	-1.46030	1.76002	-9.63255	2.48984	Greater	0.23380	4.136e-14
N172	0.072866	0.041238	-0.32502	-0.28492	-1.02969	0.33718	Greater	0.22406	4.136e-14
N185	0.114975	0.069712	-0.46759	-0.32819	-0.79693	0.10159	Greater	0.19480	4.136e-14
N88	0.018685	0.019546	-0.39161	-0.44168	-0.76305	0.02313	Greater	0.18829	4.136e-14
N149	2e-06	3e-06	-1.00103	0.00000	-7.97178	0.98735	Greater	0.18615	4.136e-14
N34	0.004435	0.000774	-1.21802	-0.22382	-2.39870	0.55134	Greater	0.18419	4.136e-14
N65	2e-06	2e-06	-1.34879	0.00000	-7.63603	0.40547	Greater	0.18234	4.136e-14
N180	0.15609	0.07084	-0.41720	-0.46201	-0.83908	0.00399	Greater	0.18155	4.136e-14
N28	0.082845	0.052628	-0.44644	-0.41477	-0.82175	0.00349	Greater	0.17747	4.136e-14
N24	1e-06	1e-06	-1.51151	0.00000	-8.35397	0.00000	Greater	0.15610	4.136e-14
N97	0.092636	0.062401	-0.56909	-0.72544	-1.17064	0.01692	Greater	0.14881	1.485e-13
N175	0.24611	0.128328	-0.51985	-0.46227	-0.79325	-0.18386	Greater	0.14257	4.136e-14
N37	0.010356	0.010631	-1.75618	-0.31436	-7.61997	0.44882	Greater	0.14084	4.136e-14
N144	0.011287	0.000545	-2.53301	-0.23962	-8.56713	2.03933	Greater	0.13921	4.136e-14
N171	0.16796	0.077914	-0.57177	-0.65262	-1.09989	-0.15498	Greater	0.13710	4.136e-14
N173	0.136601	0.075007	-0.75705	-0.72971	-1.40554	-0.00390	Greater	0.12871	6.293e-13
N82	0.003554	2e-06	-2.28140	-0.09182	-7.22475	0.00000	Greater	0.12673	1.34028e-12
N119	0.004118	0.020783	-1.91547	-0.69315	-7.77591	1.07651	Greater	0.12384	8.622e-10
N94	0.020169	2e-06	-2.78261	0.00000	-8.56076	0.98052	Greater	0.11242	2.19604e-10
N134	0.008437	0.000433	-2.31008	-1.65894	-7.76811	1.45873	Greater	0.10286	1.42361e-08
N89	0.137595	0.111301	-1.08680	-0.88008	-1.91323	0.02140	Greater	0.09443	2.7222e-06
N5	0.178489	0.129838	-0.79333	-0.62217	-1.17709	-0.26008	Greater	0.09365	2.4678e-07
N174	0.132184	0.071384	-0.93514	-0.74700	-1.20449	-0.26015	Greater	0.08605	3.7425e-05
N111	0.031146	0.008108	-1.11789	-0.88377	-1.68814	-0.16551	Greater	0.08243	0.0062046
N4	0.006261	0.001421	-1.06246	-1.79561	-2.66292	0.00000	Greater	0.07399	0.000100372
N43	0.197816	0.098408	-0.79603	-0.72042	-1.12396	-0.40289	Greater	0.06913	0.00060249
N26	0.098031	0.053979	-0.92209	-1.06107	-1.59160	-0.24483	Greater	0.06835	0.0011828
N166	0.30652	0.121868	-0.88055	-0.84182	-1.25305	-0.41661	Greater	0.06407	0.0011828
N105	0.254159	0.076276	-0.87620	-0.86800	-1.18747	-0.46410	Greater	0.05116	0.026955
N170	0.395391	0.155732	-0.87624	-0.93248	-1.19637	-0.59746	Greater	0.04405	0.052806
N98	0.005558	3e-06	-3.53441	-5.81711	-7.94236	0.40547	Greater	0.04299	0.0582
N177	0.104192	0.02762	-1.14195	-1.15295	-1.63874	-0.50273	Greater	0.03111	0.33504
N188	0.021998	0.021806	-3.17502	-0.29746	-9.10365	0.52247	Greater	0.02241	0.62349
N109	0.005816	3e-06	-3.01908	-1.74894	-8.08687	0.49723	Greater	0.01597	0.966
N10	0.036158	0.010933	-1.59993	-1.02833	-1.47288	-0.48671	Greater	0.01259	0.966
N73	0.003607	2e-06	-3.95466	-7.23129	-7.61727	0.00000	Lesser	-0.00286	0.966
N84	2e-06	1e-06	-2.87040	-0.69315	-8.69492	0.00000	Lesser	-0.00405	0.966
N46	3e-06	3e-06	-4.15755	-7.30765	-8.11582	0.00000	Lesser	-0.02230	0.62349
N127	0.016638	0.000277	-3.66418	-4.50503	-8.64816	0.40547	Lesser	-0.02440	0.739
N157	0.012716	0.000181	-3.98720	-7.45732	-8.61114	0.40547	Lesser	-0.03843	0.1046
N3	0.00938	0.002557	-2.23719	-1.63488	-2.36106	-0.76724	Lesser	-0.04075	0.12114
N103	0.034293	0.030173	-3.63671	-0.42893	-9.38673	0.49137	Lesser	-0.04087	0.077242
N54	0.00805	0.018934	-4.69275	-7.52023	-8.40485	0.54228	Lesser	-0.04775	0.028756
N63	0.044934	0.259793	-4.07883	-7.75598	-9.69505	1.76150	Lesser	-0.04993	0.021552
N66	0.027064	0.064954	-3.59178	-1.35539	-9.24818	0.47183	Lesser	-0.05412	0.0097393
N155	0.00893	2e-06	-4.17719	-7.48885	-8.86007	0.40547	Lesser	-0.07381	0.000100936
N68	0.034355	0.070009	-3.71934	-0.85290	-9.46234	0.44920	Lesser	-0.07548	6.8832e-05
N140	0.033746	0.00161	-3.07507	-2.40357	-4.84156	-1.11731	Lesser	-0.10113	1.87068e-08
N141	0.044252	0.121471	-3.59135	-2.73131	-9.65899	1.45885	Lesser	-0.11406	1.14816e-10
N150	0.018297	3e-06	-4.27703	-3.77744	-9.00549	-0.25710	Lesser	-0.13008	1.00159e-13
N186	0.050899	0.033144	-3.85147	-1.01713	-9.60602	0.00000	Lesser	-0.13433	4.136e-14
N169	0.461063	0.071302	-2.06785	-1.97784	-2.39966	-1.62037	Lesser	-0.13872	4.136e-14
N118	0.02054	0.001141	-4.37706	-4.42333	-8.89994	-0.40279	Lesser	-0.15178	1.66089e-11
N64	0.016086	3e-06	-5.20878	-8.06380	-9.28508	0.40547	Lesser	-0.15793	4.136e-14
N151	0.059763	3e-06	-4.37309	-2.54824	-9.99660	0.76872	Lesser	-0.16007	4.136e-14
N101	0.02161	2e-06	-5.09721	-8.48229	-9.30068	0.10715	Lesser	-0.17313	4.136e-14
N67	0.013873	2e-06	-5.12774	-8.33519	-9.19150	-0.15416	Lesser	-0.17511	4.136e-14
N136	0.016453	0.000576	-3.99916	-3.65416	-9.14340	-0.60257	Lesser	-0.17855	4.136e-14
N47	0.010304	2e-06	-5.78679	-8.12316	-8.63917	-0.47191	Lesser	-0.20639	4.136e-14
N153	0.028465	0.001292	-5.02294	-8.76390	-9.52501	0.24102	Lesser	-0.20683	4.136e-14
N69	0.021707	0.008965	-5.30511	-8.61275	-9.23468	-0.22845	Lesser	-0.21288	4.136e-14
N167	0.143801	0.145708	-3.77429	-1.90517	-5.64290	-0.76581	Lesser	-0.21300	4.136e-14
N99	0.008937	3e-06	-6.33322	-7.99587	-8.43069	-7.14441	Lesser	-0.21407	4.136e-14
N130	0.01465	0.000259	-4.94453	-7.87601	-9.08772	-1.70041	Lesser	-0.21802	4.136e-14
N76	0.034926	0.1316	-4.94815	-9.02588	-9.99263	0.47258	Lesser	-0.22012	4.136e-14
N78	0.006392	2e-06	-6.13411	-8.15498	-8.80380	-0.40547	Lesser	-0.23923	4.136e-14
N117	0.039571	0.000655	-4.82934	-2.73172	-9.85003	-0.10986	Lesser	-0.24623	4.136e-14
N137	0.030435	0.000502	-4.29759	-3.59080	-9.41626	-1.07497	Lesser	-0.25038	4.136e-14
N145	0.030689	2e-06	-5.01313	-8.38389	-9.66173	-0.55927	Lesser	-0.26009	4.136e-14
N87	0.027234	6e-06	-4.54845	-2.14116	-9.54175	-1.02133	Lesser	-0.26290	4.136e-14
N114	0.010438	3e-06	-6.05251	-6.60530	-8.53083	-5.26786	Lesser	-0.26372	4.136e-14
N75	0.016619	2e-06	-5.98060	-8.51409	-9.35379	-0.38480	Lesser	-0.26448	4.136e-14
N152	0.028493	0.001188	-5.72471	-8.70168	-9.46014	-0.58823	Lesser	-0.27103	4.136e-14
N148	0.032784	0.273336	-4.94642	-3.92823	-9.46223	-1.42930	Lesser	-0.27153	4.136e-14
N138	0.02433	0.563424	-4.72588	-3.89415	-9.14505	-1.52606	Lesser	-0.27333	4.136e-14
N124	0.01229	0.000614	-6.34417	-8.37078	-9.00778	-2.62311	Lesser	-0.30407	4.136e-14
N106	0.015119	2e-06	-5.90432	-8.10410	-8.80192	-2.33583	Lesser	-0.34033	4.136e-14
N91	0.063102	0.017846	-5.48053	-9.00356	-10.12128	-0.52941	Lesser	-0.34742	4.136e-14
N163	0.060446	2e-06	-5.58238	-7.50604	-10.06369	-1.03269	Lesser	-0.37972	4.136e-14
N112	0.031219	3e-06	-6.19636	-8.32966	-9.51242	-2.45556	Lesser	-0.38338	4.136e-14
N147	0.046617	0.000756	-5.75028	-4.91442	-9.86237	-2.05183	Lesser	-0.40589	4.136e-14
N129	0.035443	0.000454	-6.07074	-8.75216	-9.60637	-2.67124	Lesser	-0.40993	4.136e-14
N107	0.009704	2e-06	-7.92301	-8.42332	-8.77207	-7.79996	Lesser	-0.42112	4.136e-14
N86	0.122371	0.002931	-5.80663	-9.29152	-10.76854	-0.86955	Lesser	-0.43962	4.136e-14
N159	0.042881	2e-06	-6.45308	-9.22901	-10.02407	-1.38570	Lesser	-0.44141	4.136e-14
N132	0.029479	0.002669	-6.44265	-8.75242	-9.70519	-2.94752	Lesser	-0.44427	4.136e-14
N57	0.013629	2e-06	-8.46848	-8.49352	-9.12003	-7.67136	Lesser	-0.46609	4.136e-14
N81	0.037774	0.018884	-7.10267	-9.40055	-9.91575	-1.23507	Lesser	-0.47133	4.136e-14
N158	0.076008	0.003097	-6.66403	-10.12286	-10.55635	-0.83424	Lesser	-0.48155	4.136e-14
N90	0.01176	2e-06	-8.63008	-8.79981	-9.02305	-8.42585	Lesser	-0.48915	4.136e-14
N62	0.01821	2e-06	-8.62667	-8.63076	-9.04375	-8.36116	Lesser	-0.48925	4.136e-14
N108	0.008057	2e-06	-8.67523	-8.81552	-9.16649	-8.31544	Lesser	-0.49153	4.136e-14
N80	0.013808	2e-06	-8.62144	-8.77648	-9.13465	-8.17745	Lesser	-0.49228	4.136e-14
N156	0.13132	3e-06	-6.14431	-4.15063	-10.86374	-1.62521	Lesser	-0.49515	4.136e-14
N135	0.065082	0.004491	-6.55705	-9.21407	-10.45152	-2.48670	Lesser	-0.50161	4.136e-14
N83	0.069077	3e-06	-6.55939	-10.13519	-10.56472	-0.94031	Lesser	-0.50586	4.136e-14
N110	0.011953	2e-06	-8.62635	-8.91939	-9.33079	-8.36019	Lesser	-0.51376	4.136e-14
N48	0.037271	2e-06	-7.24935	-9.53777	-9.93792	-2.84574	Lesser	-0.51437	4.136e-14
N92	0.047093	2e-06	-7.15020	-9.81949	-10.20068	-0.95456	Lesser	-0.51565	4.136e-14
N49	0.013669	3e-06	-8.63449	-8.82237	-9.38265	-8.07745	Lesser	-0.51594	4.136e-14
N122	0.022311	0.00211	-7.87675	-8.98377	-9.52186	-5.33076	Lesser	-0.51846	4.136e-14
N96	0.014474	2e-06	-8.79616	-8.82203	-9.16178	-8.48694	Lesser	-0.51891	4.136e-14
N59	0.016899	2e-06	-8.75658	-8.89227	-9.34906	-8.34640	Lesser	-0.52496	4.136e-14
N116	0.042083	0.001207	-7.46406	-9.63243	-10.07580	-4.76087	Lesser	-0.53616	4.136e-14
N55	0.020196	3e-06	-8.92070	-8.99119	-9.23363	-8.68941	Lesser	-0.54710	4.136e-14
N52	0.01674	2e-06	-8.93432	-9.00159	-9.31857	-8.68688	Lesser	-0.55444	4.136e-14
N77	0.020056	2e-06	-8.93213	-9.00549	-9.44553	-8.46076	Lesser	-0.56070	4.136e-14
N154	0.078493	0.002518	-7.41057	-10.12169	-10.47595	-1.94504	Lesser	-0.57040	4.136e-14
N125	0.039165	0.001126	-7.78359	-9.66789	-10.09297	-5.99159	Lesser	-0.57146	4.136e-14
N128	0.06205	0.023638	-7.29335	-9.88793	-10.35366	-2.93607	Lesser	-0.57591	4.136e-14
N162	0.225274	0.015568	-6.96962	-10.88948	-11.44128	-2.04051	Lesser	-0.57870	4.136e-14
N56	0.019663	2e-06	-9.10098	-9.21619	-9.47999	-8.81096	Lesser	-0.59771	4.136e-14
N45	0.029571	2e-06	-9.13669	-9.17522	-9.37684	-8.89114	Lesser	-0.59844	4.136e-14
N74	0.017703	3e-06	-9.12314	-9.20256	-9.58507	-8.78360	Lesser	-0.60529	4.136e-14
N126	0.023619	0.001918	-9.09627	-9.28489	-9.62069	-8.86517	Lesser	-0.61625	4.136e-14
N123	0.025882	0.000824	-9.13561	-9.22326	-9.79518	-8.55353	Lesser	-0.61845	4.136e-14
N50	0.026528	3e-06	-9.15834	-9.26927	-9.70361	-8.69506	Lesser	-0.62128	4.136e-14
N53	0.025448	2e-06	-9.21192	-9.30070	-9.59107	-8.95553	Lesser	-0.62657	4.136e-14
N58	0.02822	2e-06	-9.25894	-9.49077	-9.83478	-8.75105	Lesser	-0.64886	4.136e-14
N131	0.03432	0.001566	-9.06904	-9.49597	-9.90391	-8.95953	Lesser	-0.66324	4.136e-14
N164	0.05022	3e-06	-8.09964	-9.83092	-10.24605	-3.62901	Lesser	-0.67022	4.136e-14
N79	0.024079	2e-06	-9.46520	-9.52486	-9.93295	-9.12184	Lesser	-0.69325	4.136e-14
N70	0.032945	2e-06	-9.49100	-9.55191	-9.80893	-9.21231	Lesser	-0.70116	4.136e-14
N44	0.031917	2e-06	-9.60579	-9.73661	-10.03208	-9.34248	Lesser	-0.73558	4.136e-14
N60	0.033878	2e-06	-9.71353	-9.78583	-9.97753	-9.46459	Lesser	-0.76175	4.136e-14
N100	0.053706	2e-06	-9.87564	-9.94064	-10.22304	-9.59875	Lesser	-0.80161	4.136e-14
N115	0.048534	2e-06	-10.02749	-10.15191	-10.49284	-9.58854	Lesser	-0.82858	4.136e-14
N51	0.074332	3e-06	-10.24814	-10.30226	-10.54354	-9.99305	Lesser	-0.88253	4.136e-14
N85	0.078312	3e-06	-10.26662	-10.28498	-10.53767	-10.02911	Lesser	-0.88698	4.136e-14
N113	0.063364	3e-06	-10.38567	-10.41166	-10.64911	-10.14207	Lesser	-0.91296	4.136e-14

Propertites of Heterotachy Phylogeny of ACAA2 proteinsNatural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios; 100 iteration of random 50%-alignment jackknife

Propertites of Heterotachy Phylogeny of ACAA2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife