Propertites of Heterotachy Phylogeny of HINT2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N98	2e-06	0.057396	10.46350	10.75955	10.25339	10.98852	Greater	0.89707	2.596e-14
N70	0.01763	0.958774	6.19055	4.08953	3.14006	12.45030	Greater	0.76480	2.596e-14
N88	2e-06	0.033256	8.03521	9.98361	8.16849	10.66290	Greater	0.69385	2.596e-14
N44	2e-06	0.027781	7.81699	10.17554	0.40547	10.89818	Greater	0.67210	2.596e-14
N13	0.033728	0.184887	5.24755	2.45500	1.61511	11.46531	Greater	0.64514	2.596e-14
N84	2e-06	0.034891	6.66257	9.97019	1.56771	10.67734	Greater	0.62626	2.596e-14
N17	0.047823	1.019968	2.91138	2.88768	2.31178	3.51778	Greater	0.62072	2.596e-14
N73	0.045465	0.598191	2.67246	2.62807	2.20099	3.09541	Greater	0.60605	2.596e-14
N117	0.06429	1.15165	2.78065	2.85425	2.20019	3.44472	Greater	0.60041	2.596e-14
N3	0.142745	1.078398	2.49082	2.44698	2.00024	2.93579	Greater	0.58386	2.596e-14
N8	0.093749	1.4111	2.61842	2.71783	1.94039	3.31453	Greater	0.57424	2.596e-14
N1	0.024717	0.344903	2.55448	2.59812	1.82392	3.27978	Greater	0.55903	2.596e-14
N14	2e-06	0.031587	5.63080	8.91771	0.40547	10.56251	Greater	0.54329	2.596e-14
N53	0.273481	1.901581	2.07981	2.21750	1.73684	2.67192	Greater	0.50297	2.596e-14
N24	0.079111	0.75252	2.30698	2.73579	1.77793	3.40021	Greater	0.48516	2.596e-14
N116	0.01891	0.206607	3.61969	1.72481	0.69251	3.95325	Greater	0.47807	2.596e-14
N47	0.01331	0.027324	3.48783	2.79061	0.66714	8.09601	Greater	0.46849	2.596e-14
N80	0.013087	0.047935	3.91364	1.74621	0.72777	9.95679	Greater	0.46793	2.596e-14
N11	0.030441	0.055579	4.01297	1.14609	0.43748	10.17618	Greater	0.44385	2.596e-14
N30	0.02614	0.315304	3.77987	2.38527	0.60484	11.60339	Greater	0.43696	2.596e-14
N10	0.018571	0.041544	4.24872	1.70466	0.23392	9.83571	Greater	0.42874	2.596e-14
N37	0.05184	0.190964	1.49358	1.46526	0.96124	1.99525	Greater	0.41763	2.596e-14
N86	3e-06	0.000982	4.52021	7.26005	0.00000	9.42006	Greater	0.41150	2.596e-14
N118	0.387856	1.312746	1.29039	1.27858	0.88876	1.70248	Greater	0.38403	2.596e-14
N45	0.301326	1.874474	1.46442	1.85632	0.96525	2.35199	Greater	0.38376	2.596e-14
N87	3e-06	0.007012	3.82947	0.40547	0.00000	9.00867	Greater	0.35518	2.596e-14
N99	3e-06	2e-06	4.20157	0.00000	-0.40547	9.63820	Greater	0.34521	2.596e-14
N95	3e-06	0.050464	2.63833	1.26541	0.00000	9.85209	Greater	0.34152	2.596e-14
N27	0.001241	0.06363	2.44994	1.15077	0.00000	10.17924	Greater	0.33704	2.596e-14
N38	2e-06	2e-06	2.19862	0.81828	0.00000	9.95399	Greater	0.29712	2.596e-14
N56	0.053966	0.144399	0.88017	0.93420	0.38990	1.55569	Greater	0.27415	2.596e-14
N35	2e-06	0.034262	3.44790	0.28856	-0.69315	10.24486	Greater	0.27090	2.596e-14
N33	0.026376	0.775707	1.25346	2.66342	-2.33928	4.54065	Greater	0.26405	2.596e-14
N51	0.168409	0.698441	1.08627	1.30273	-0.22063	2.37216	Greater	0.26116	2.596e-14
N93	2e-06	0.025196	2.20891	0.40547	0.00000	8.51258	Greater	0.26069	2.596e-14
N40	3e-06	0.006863	3.25857	0.00000	0.00000	9.66939	Greater	0.25992	2.596e-14
N92	0.015442	0.039501	1.88113	0.94626	-0.40547	8.64077	Greater	0.25848	2.596e-14
N50	0.09497	0.085118	2.21118	1.15093	-0.69458	3.24465	Greater	0.25682	2.596e-14
N106	2e-06	0.007981	2.91182	0.00000	-0.69315	9.80885	Greater	0.24236	2.596e-14
N23	2e-06	1e-06	3.45236	0.00000	-0.69315	10.18303	Greater	0.24122	2.596e-14
N115	0.149464	0.26445	0.74702	0.79871	0.24322	1.35614	Greater	0.23978	2.596e-14
N5	0.009581	0.0421	1.44401	0.62977	-0.40547	9.35893	Greater	0.23510	2.596e-14
N48	0.249778	0.723109	0.70292	0.95734	0.00386	1.66861	Greater	0.22176	2.596e-14
N41	0.191697	0.277768	0.63106	0.69822	0.22663	1.10814	Greater	0.21499	2.596e-14
N76	0.27473	0.47692	0.67480	0.64641	0.12583	1.17424	Greater	0.21446	2.596e-14
N78	0.015638	0.017743	1.43441	0.39313	-0.67930	8.50025	Greater	0.18703	2.596e-14
N77	0.025893	0.035673	0.58294	0.60876	-0.01405	1.22294	Greater	0.17625	2.596e-14
N21	2e-06	2e-06	2.57741	0.00000	-0.69315	9.59941	Greater	0.17575	2.596e-14
N83	0.035318	0.05804	0.43968	0.63421	-0.08563	1.16547	Greater	0.16522	2.596e-14
N90	2e-06	1e-06	2.41661	0.00000	-0.69315	8.80538	Greater	0.12856	7.9225e-14
N110	0.15643	0.244158	0.38612	0.30520	-0.25190	0.95960	Greater	0.12329	6.7507e-11
N64	0.012276	2e-06	0.41530	0.13299	-2.28532	7.17204	Greater	0.12259	3.2844e-12
N81	2e-06	0.044861	0.14046	0.00000	-8.00637	1.69120	Greater	0.09952	1.6656e-08
N113	0.083581	0.071633	0.14818	0.14486	-0.48782	0.77767	Greater	0.05897	0.0045216
N74	0.079245	0.095202	0.08704	0.11620	-1.91650	1.97071	Greater	0.05529	0.0035584
N104	0.106935	0.257298	-1.74727	1.07225	-9.24672	1.99527	Greater	0.04721	0.01138
N7	0.044842	0.06364	-1.08847	0.32855	-2.75779	1.69760	Greater	0.04391	0.016628
N91	2e-06	2e-06	0.00236	0.00000	0.00000	0.00000	Greater	0.00819	0.3206
N52	0.268484	0.138264	-0.22406	-0.24474	-1.15266	0.80918	Lesser	-0.02037	0.2574
N42	0.035888	2e-06	-2.22457	0.07829	-9.27244	1.27964	Lesser	-0.04332	0.016628
N22	2e-06	1e-06	-0.15530	0.00000	-0.69315	0.00000	Lesser	-0.05515	0.0035584
N102	0.030977	0.030192	-2.31637	0.00000	-9.21179	1.34693	Lesser	-0.06434	0.0005371
N16	0.027581	3e-06	-3.18679	-8.04730	-9.44002	2.36308	Lesser	-0.06505	0.0005371
N20	2e-06	1e-06	-2.18004	-0.69315	-8.84779	1.02036	Lesser	-0.06963	0.00015411
N100	0.040838	0.040981	-2.08661	-0.00883	-9.00534	0.93344	Lesser	-0.07205	8.946e-05
N75	0.164646	0.029649	-1.22354	-0.40239	-1.90390	0.72837	Lesser	-0.08894	2.2347e-06
N65	0.028478	0.042082	-2.62075	-0.03780	-9.31348	0.93847	Lesser	-0.09326	1.5585e-07
N58	2e-06	1e-06	-0.26299	-0.69315	-0.69315	0.00000	Lesser	-0.09598	1.4154e-06
N46	0.27407	0.136962	-0.44997	-0.42035	-1.02729	0.21808	Lesser	-0.10427	1.62945e-08
N32	2e-06	1e-06	-0.30638	-0.69315	-0.69315	0.00000	Lesser	-0.11570	8.2674e-10
N34	2e-06	1e-06	-0.31533	-0.69315	-0.69315	0.00000	Lesser	-0.11765	5.388e-11
N25	0.043903	0.013158	-1.29117	-0.86010	-8.14729	0.97500	Lesser	-0.11846	1.13547e-11
N96	3e-06	2e-06	-2.25198	-0.40547	-8.47209	0.00000	Lesser	-0.12046	4.246e-12
N85	0.003167	0.006058	-2.50465	-0.40547	-8.78925	0.00000	Lesser	-0.12928	8.64e-14
N31	2e-06	1e-06	-0.36482	-0.69315	-0.69315	0.00000	Lesser	-0.13922	2.596e-14
N103	0.249941	0.094136	-1.16739	-0.31671	-0.99111	0.16537	Lesser	-0.14151	4.6982e-14
N2	2e-06	1e-06	-0.42820	-0.69315	-0.69315	0.00000	Lesser	-0.16462	2.596e-14
N26	3e-06	2e-06	-2.67589	-0.40547	-9.55577	0.00000	Lesser	-0.16916	2.596e-14
N4	0.012912	0.008137	-2.44511	-1.37044	-8.58914	0.00000	Lesser	-0.20502	2.596e-14
N12	2e-06	1e-06	-1.96962	-0.69315	-5.64545	0.00000	Lesser	-0.20570	2.596e-14
N89	0.035542	0.003351	-2.96501	-0.76557	-9.31443	0.25791	Lesser	-0.20912	2.596e-14
N49	0.203085	0.009458	-3.17074	-0.97949	-10.51549	1.15830	Lesser	-0.21680	2.596e-14
N82	0.009993	2e-06	-4.02952	-0.69315	-8.96233	0.00000	Lesser	-0.24290	2.596e-14
N67	0.076786	0.030665	-3.04202	-0.64810	-10.03157	0.14554	Lesser	-0.24827	2.596e-14
N39	0.07247	3e-06	-3.51871	-0.63982	-9.88687	0.12521	Lesser	-0.25706	2.596e-14
N55	0.001327	2e-06	-4.19365	-7.88833	-8.72038	0.00000	Lesser	-0.26657	2.596e-14
N79	2e-06	2e-06	-3.72104	-0.69315	-9.14078	0.00000	Lesser	-0.27370	2.596e-14
N36	0.039772	3e-06	-4.82381	-9.11162	-9.85866	0.00000	Lesser	-0.30450	2.596e-14
N61	0.028317	2e-06	-4.23323	-5.68698	-10.27784	0.00000	Lesser	-0.30846	2.596e-14
N111	0.083845	0.044395	-4.52578	-1.65810	-10.71588	0.21651	Lesser	-0.34169	2.596e-14
N9	0.0507	0.002652	-3.94112	-2.03400	-10.00514	-0.15482	Lesser	-0.34447	2.596e-14
N54	0.095629	3e-06	-5.40942	-9.83833	-10.82631	0.71097	Lesser	-0.36239	2.596e-14
N112	0.113547	0.011918	-4.06890	-1.48586	-10.59031	-0.12163	Lesser	-0.37482	2.596e-14
N94	0.048237	0.002766	-4.97930	-8.29163	-9.81024	-0.40455	Lesser	-0.37890	2.596e-14
N97	0.017967	3e-06	-6.14510	-8.80463	-9.26927	-1.41853	Lesser	-0.40636	2.596e-14
N15	0.017929	2e-06	-6.38873	-8.78409	-9.49514	0.00000	Lesser	-0.41547	2.596e-14
N107	0.24781	0.040191	-4.29390	-1.39440	-11.26271	-0.29626	Lesser	-0.42436	2.596e-14
N108	0.079819	0.009108	-5.76941	-8.78186	-10.73775	-0.25287	Lesser	-0.43178	2.596e-14
N72	0.141171	0.013865	-4.24262	-2.26543	-10.33482	-0.76986	Lesser	-0.43308	2.596e-14
N29	0.112836	3e-06	-6.31019	-10.04436	-10.68169	-0.01632	Lesser	-0.45803	2.596e-14
N28	0.053624	2e-06	-6.37418	-9.81420	-10.32812	-0.40547	Lesser	-0.46128	2.596e-14
N19	0.050804	2e-06	-6.79647	-9.62964	-10.29052	-0.40547	Lesser	-0.47217	2.596e-14
N6	0.08108	2e-06	-6.52377	-10.00100	-10.76330	-0.35353	Lesser	-0.47595	2.596e-14
N63	0.081926	0.019715	-5.57891	-8.85123	-10.48731	-0.59485	Lesser	-0.48988	2.596e-14
N69	0.02074	2e-06	-6.76011	-9.34102	-10.21200	-0.40547	Lesser	-0.50056	2.596e-14
N60	0.064396	0.011177	-6.18699	-9.46700	-10.62155	-0.85606	Lesser	-0.53109	2.596e-14
N101	0.082066	2e-06	-6.73963	-10.01607	-10.78819	-0.94286	Lesser	-0.54176	2.596e-14
N62	0.054319	2e-06	-7.20484	-10.01951	-10.59877	-1.42399	Lesser	-0.56193	2.596e-14
N114	0.089652	2e-06	-7.09321	-10.12345	-11.08539	-1.50645	Lesser	-0.56940	2.596e-14
N105	0.215514	0.004018	-6.06319	-4.20839	-11.43397	-1.14367	Lesser	-0.59651	2.596e-14
N18	0.03904	3e-06	-9.77281	-9.81524	-10.20085	-9.44094	Lesser	-0.69331	2.596e-14
N57	0.050339	3e-06	-9.77306	-10.03622	-10.47439	-9.57027	Lesser	-0.72015	2.596e-14
N59	0.068257	3e-06	-9.34021	-10.19978	-10.80418	-9.36576	Lesser	-0.74138	2.596e-14
N66	0.0718	2e-06	-10.39635	-10.47944	-10.73342	-10.11543	Lesser	-0.80573	2.596e-14
N43	0.111968	3e-06	-10.52602	-10.54297	-10.97353	-10.10834	Lesser	-0.82673	2.596e-14
N109	0.097778	2e-06	-10.60322	-10.70671	-11.56338	-9.89649	Lesser	-0.83278	2.596e-14
N68	0.103519	2e-06	-10.66868	-10.76258	-11.20380	-10.24026	Lesser	-0.84936	2.596e-14
N71	0.221897	2e-06	-11.53160	-11.58626	-11.82699	-11.33381	Lesser	-0.96274	2.596e-14