Propertites of Heterotachy Phylogeny of HTRA2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N64	2e-06	0.030359	9.87949	9.62440	9.14441	10.76001	Greater	0.92199	4.07e-14
N60	2e-06	0.018791	9.18565	9.29611	8.86170	9.73329	Greater	0.89101	4.07e-14
N69	2e-06	0.015232	9.02188	9.09644	8.66155	9.46090	Greater	0.88366	4.07e-14
N17	0.003542	0.180462	8.05304	6.09451	4.21680	11.55548	Greater	0.86096	4.07e-14
N10	0.005726	0.295023	8.17315	5.63243	4.38777	12.27929	Greater	0.86029	4.07e-14
N77	3e-06	0.009832	8.13971	8.24486	7.74284	9.04955	Greater	0.85498	4.07e-14
N16	3e-06	0.007332	6.62720	7.13595	4.16408	8.04985	Greater	0.79995	4.07e-14
N153	2e-06	0.120456	7.95335	10.02196	4.09434	10.88080	Greater	0.77661	4.07e-14
N6	3e-06	0.000233	4.60971	4.57127	4.34381	4.88658	Greater	0.75502	4.07e-14
N165	0.018235	1.368969	4.93221	4.61004	3.80789	5.63343	Greater	0.75313	4.07e-14
N71	0.005959	0.144153	5.83226	3.57559	2.77573	10.58559	Greater	0.75183	4.07e-14
N13	2e-06	6.9e-05	5.12465	3.82864	3.52636	7.62364	Greater	0.74832	4.07e-14
N15	0.007645	0.123923	5.27099	3.34009	2.78551	10.58890	Greater	0.73195	4.07e-14
N74	2e-06	0.000319	5.85618	5.20126	4.36945	8.74154	Greater	0.70892	4.07e-14
N112	0.013814	0.382406	3.76225	3.80177	3.17361	4.28156	Greater	0.69537	4.07e-14
N173	0.003368	0.10597	5.23355	3.41949	2.69955	10.36513	Greater	0.69211	4.07e-14
N25	0.030134	0.813019	3.64129	3.56081	3.16116	4.01854	Greater	0.68951	4.07e-14
N171	2e-06	0.012078	7.15658	9.24392	5.56692	10.24344	Greater	0.68672	4.07e-14
N70	0.003417	0.044205	5.79095	6.39526	2.34722	9.92034	Greater	0.67583	4.07e-14
N4	3e-06	0.059552	5.55403	3.92664	2.87137	10.29762	Greater	0.64683	4.07e-14
N23	2e-06	0.018966	5.79629	7.65610	2.23609	9.41800	Greater	0.64052	4.07e-14
N169	2e-06	2.2e-05	3.13783	2.56495	2.35138	4.44265	Greater	0.61704	4.07e-14
N54	0.003864	0.030536	5.10866	2.79376	1.85990	9.78642	Greater	0.61006	4.07e-14
N1	0.019435	0.222421	4.44084	2.78052	1.65001	5.33873	Greater	0.60444	4.07e-14
N106	0.101285	1.506965	2.82175	2.86541	2.10305	3.39112	Greater	0.59717	4.07e-14
N156	2e-06	0.003377	5.42671	7.47449	3.80666	7.86978	Greater	0.57430	4.07e-14
N127	0.088353	0.496675	3.96589	1.86837	1.11104	4.98132	Greater	0.52501	4.07e-14
N172	0.082437	0.459432	2.21589	2.12968	1.68520	2.58029	Greater	0.50239	4.07e-14
N12	0.007792	0.008044	4.64390	4.85981	1.40804	9.78648	Greater	0.50215	4.07e-14
N168	2e-06	0.11122	5.32971	5.69877	0.00000	11.51172	Greater	0.48841	4.07e-14
N139	0.227111	1.031364	1.76440	1.77027	1.54516	1.99669	Greater	0.45064	4.07e-14
N98	0.150488	0.760252	1.85027	1.81486	1.39648	2.26954	Greater	0.44597	4.07e-14
N66	3e-06	0.002424	4.08530	3.68888	0.00000	7.76160	Greater	0.44209	4.07e-14
N31	0.004051	0.058355	3.29073	2.06021	0.76159	4.06188	Greater	0.42667	4.07e-14
N20	0.008493	0.045505	3.96581	4.07754	1.05013	9.56983	Greater	0.42397	4.07e-14
N80	0.046262	0.169874	1.73979	1.63214	1.14424	2.25041	Greater	0.41222	4.07e-14
N38	0.068939	0.213342	1.73605	1.62402	1.01933	2.31016	Greater	0.40086	4.07e-14
N28	0.016452	0.150762	1.82418	1.81861	1.17560	2.43397	Greater	0.39975	4.07e-14
N93	0.041326	0.288765	1.66060	1.73891	1.06666	2.31962	Greater	0.39125	4.07e-14
N108	0.172648	0.237779	1.83069	1.78184	0.74205	2.75554	Greater	0.37832	4.07e-14
N136	0.017099	0.088242	1.42866	1.42597	1.04294	1.80493	Greater	0.35614	4.07e-14
N124	0.12005	0.357389	1.29711	1.28936	1.09916	1.49279	Greater	0.33600	4.07e-14
N73	0.008582	0.020639	2.94007	1.04531	0.34396	8.19091	Greater	0.33498	4.07e-14
N158	0.007325	0.03812	1.99495	1.88575	0.43007	2.88900	Greater	0.33418	4.07e-14
N110	0.011817	0.052922	3.26695	1.44656	0.07119	8.87382	Greater	0.33104	4.07e-14
N157	0.008454	0.060019	2.08212	1.55969	0.66889	3.07179	Greater	0.31766	4.07e-14
N142	0.024079	0.053059	1.38588	1.44857	0.56486	2.10896	Greater	0.31524	4.07e-14
N72	0.130792	0.368505	1.24080	1.17994	0.83904	1.58864	Greater	0.30538	4.07e-14
N45	0.083938	0.146752	1.24807	1.27255	0.60034	1.83568	Greater	0.29527	4.07e-14
N174	0.02997	0.093142	1.27595	1.15258	0.71554	1.72272	Greater	0.29094	4.07e-14
N167	0.036041	0.003809	3.25743	2.32383	-0.78954	9.10905	Greater	0.27960	4.07e-14
N48	0.082244	0.223369	1.13763	1.11055	0.75865	1.50246	Greater	0.27770	4.07e-14
N76	0.00684	0.006252	2.81964	1.40636	-0.25884	7.91206	Greater	0.27272	4.07e-14
N145	0.000862	0.002635	2.25982	1.75547	-0.90199	6.02466	Greater	0.22825	4.07e-14
N140	0.0042	0.004211	1.50136	2.46925	-0.60874	4.15364	Greater	0.22343	4.07e-14
N59	0.008031	0.01421	1.01993	1.06493	0.34334	1.67369	Greater	0.22121	4.07e-14
N143	0.078867	0.155033	0.94617	1.20008	0.28676	1.59328	Greater	0.21754	4.07e-14
N132	0.01585	0.053391	1.00097	1.14352	0.11960	1.84357	Greater	0.21174	4.07e-14
N105	0.187435	0.735981	0.95136	0.96988	0.31101	1.64610	Greater	0.21037	4.07e-14
N43	0.144081	0.288776	0.97220	0.91899	0.27072	2.03775	Greater	0.20822	4.07e-14
N75	0.021556	0.051548	0.88430	0.87959	0.43637	1.34288	Greater	0.19875	4.07e-14
N89	0.053941	0.146062	0.99861	1.35220	-0.17890	2.59272	Greater	0.19700	4.07e-14
N33	0.003116	0.03763	2.07615	1.17913	-1.06594	5.08879	Greater	0.19671	4.07e-14
N81	0.154526	0.314094	0.93879	0.83795	0.26709	1.43872	Greater	0.19447	4.07e-14
N21	0.094193	0.241681	0.84631	0.93658	0.43320	1.29921	Greater	0.19352	4.07e-14
N180	0.023794	0.135322	0.85665	1.38527	0.02839	2.22580	Greater	0.19294	4.07e-14
N78	0.017244	0.068227	0.78901	1.07233	0.35571	1.63328	Greater	0.18110	4.07e-14
N160	0.003587	0.005344	1.77624	1.08059	-0.96605	4.03719	Greater	0.17828	4.07e-14
N133	0.269558	0.510778	0.78256	0.75588	0.47791	1.06996	Greater	0.17709	4.07e-14
N99	0.088708	0.287917	0.89769	1.09552	-0.14101	2.29540	Greater	0.17299	4.07e-14
N151	0.049612	0.116368	0.76043	0.79061	0.44264	1.11620	Greater	0.16783	4.07e-14
N22	0.017634	0.011521	1.70282	1.21469	-0.76054	3.89860	Greater	0.15926	4.07e-14
N9	0.026246	0.097085	0.65067	1.22909	-0.48260	1.86499	Greater	0.15250	4.07e-14
N94	0.017444	0.05439	0.92478	1.17165	-1.08489	2.12477	Greater	0.14015	4.07e-14
N26	0.390461	0.54459	0.63224	0.59245	0.36764	0.91865	Greater	0.13005	9.424e-14
N11	0.016164	0.004271	1.49923	1.23331	-1.74571	4.22926	Greater	0.12779	2.64926e-13
N55	0.022999	0.049135	0.62165	0.75126	0.12898	1.23081	Greater	0.12603	5.814e-13
N42	0.02849	0.043507	0.63666	0.67015	0.00237	1.40891	Greater	0.12498	1.47644e-12
N85	0.017526	0.028551	0.79747	0.86009	-0.66987	2.17309	Greater	0.12456	1.34647e-12
N56	0.062892	0.096597	0.50366	0.52847	0.20824	0.82323	Greater	0.08800	1.4697e-06
N58	0.026405	0.033784	0.41616	0.54376	-0.11682	1.05923	Greater	0.06871	0.00077254
N53	0.013752	0.014003	0.40778	0.47882	-0.29394	1.12190	Greater	0.05980	0.0051702
N18	0.037419	0.113288	0.20780	0.89871	-0.92380	1.49388	Greater	0.05768	0.0042224
N19	0.034251	0.004172	0.22364	0.62469	-1.24057	1.68327	Greater	0.03418	0.22121
N141	0.005659	0.018536	0.48743	1.00102	-2.89252	2.66266	Greater	0.03118	0.27585
N138	0.100946	0.199956	0.25684	0.53730	-0.13171	0.87862	Greater	0.02868	0.3524
N164	0.008825	0.031222	0.15239	0.72119	-2.12777	1.71764	Greater	0.02342	0.55895
N62	0.054507	0.079623	0.23034	0.29061	-0.10340	0.64393	Greater	0.00423	1
N65	3e-06	0.003979	0.65007	0.00000	-0.60451	7.09782	Greater	0.00227	1
N117	0.027948	0.023406	0.11852	0.21832	-0.29204	0.77773	Lesser	-0.00968	1
N5	0.00301	0.000285	0.53355	-2.97273	-3.80987	5.07204	Lesser	-0.00971	1
N96	0.116169	0.163942	0.06883	0.13209	-0.67862	1.02686	Lesser	-0.02176	0.55895
N163	0.010565	0.007221	0.09181	0.10925	-0.68627	1.05188	Lesser	-0.02432	0.55895
N137	0.043476	0.034715	0.10104	0.23429	-0.24497	0.56217	Lesser	-0.03227	0.2741
N92	0.279445	0.316805	0.10197	0.11641	-0.14885	0.37671	Lesser	-0.04315	0.057552
N34	0.02993	0.009046	0.19706	-0.02610	-2.89731	2.12430	Lesser	-0.05342	0.0087412
N95	0.132482	0.068526	-0.06787	0.06289	-0.81126	0.78269	Lesser	-0.05890	0.0042224
N118	0.101634	0.079441	0.03270	0.07911	-0.30755	0.42671	Lesser	-0.05917	0.0036635
N149	0.017741	0.005561	-0.08363	0.11976	-1.30440	1.13156	Lesser	-0.06577	0.00113292
N44	0.08697	0.061735	-0.01126	0.08035	-0.29427	0.38575	Lesser	-0.06898	0.0003678
N119	0.051505	0.037987	-0.09910	0.00426	-0.58687	0.48538	Lesser	-0.08191	9.2358e-06
N7	0.009847	0.000542	-0.00756	0.05724	-3.25602	1.28885	Lesser	-0.08674	2.11904e-06
N82	0.069731	0.06785	-0.34031	-0.08031	-1.54174	0.99938	Lesser	-0.09808	4.7112e-08
N3	0.016391	0.034925	-0.14742	-0.45945	-2.96912	1.47426	Lesser	-0.11312	1.4005e-10
N103	0.140397	0.015003	-0.05843	-0.56177	-2.18368	1.26423	Lesser	-0.12218	3.8844e-12
N113	0.046144	0.043076	-0.43114	0.09879	-0.82260	0.61733	Lesser	-0.12230	2.9133e-12
N57	0.008544	0.013836	-1.07599	0.14644	-2.87853	1.15745	Lesser	-0.13099	6.2073e-14
N109	0.374275	0.284019	-0.24396	-0.16327	-0.58698	0.20189	Lesser	-0.13458	4.07e-14
N170	0.001283	0.003675	-0.46653	-0.39608	-3.80791	1.47326	Lesser	-0.13932	4.07e-14
N155	0.031669	0.022137	-0.69631	0.11232	-1.69978	0.81528	Lesser	-0.14834	4.07e-14
N122	0.084702	0.032649	-0.51660	-0.35218	-1.42130	0.58016	Lesser	-0.14870	4.07e-14
N68	0.006866	0.000189	-0.47000	-0.40547	-3.85656	3.61989	Lesser	-0.15013	4.07e-14
N177	0.212463	0.140997	-0.33388	-0.29527	-0.60557	-0.01884	Lesser	-0.17269	4.07e-14
N101	0.367068	0.337177	-0.88296	-0.37943	-1.80688	0.47066	Lesser	-0.20836	4.07e-14
N63	0.012334	0.016873	-1.94455	0.13399	-8.19878	0.90025	Lesser	-0.21086	4.07e-14
N27	0.021792	0.000741	-0.63123	-1.47003	-3.58893	1.14421	Lesser	-0.21460	4.07e-14
N179	0.142084	0.112596	-0.94190	-0.97240	-2.56827	0.88043	Lesser	-0.21628	4.07e-14
N91	0.00288	0.000391	-0.49502	-1.96557	-2.62918	4.54860	Lesser	-0.22136	4.07e-14
N152	0.072293	0.005396	-1.00451	-0.16038	-3.16113	0.59336	Lesser	-0.22357	4.07e-14
N181	0.148884	0.081613	-0.57058	-0.50964	-0.96317	-0.12264	Lesser	-0.22600	4.07e-14
N36	0.014609	0.01956	-2.07045	-0.49795	-7.88055	1.12424	Lesser	-0.23453	4.07e-14
N86	0.074702	0.103905	-1.04567	-0.93112	-2.83072	0.72678	Lesser	-0.23558	4.07e-14
N147	0.00405	2e-06	-1.86103	0.00000	-8.72250	0.68452	Lesser	-0.24659	4.07e-14
N166	0.011358	0.000535	-0.77835	-1.86518	-3.20164	0.71913	Lesser	-0.25664	4.07e-14
N97	0.008556	0.000288	-0.97812	-1.23882	-3.92584	0.60042	Lesser	-0.26538	4.07e-14
N144	0.039796	0.008375	-1.14328	-1.17300	-2.20795	0.00768	Lesser	-0.30247	4.07e-14
N32	0.074049	0.004206	-1.37375	-1.52288	-3.24669	0.43892	Lesser	-0.30605	4.07e-14
N83	0.27605	0.09805	-1.07527	-0.85406	-2.00907	-0.25246	Lesser	-0.31190	4.07e-14
N175	0.205224	0.081519	-0.92772	-0.84609	-1.26186	-0.48758	Lesser	-0.31392	4.07e-14
N182	0.077627	0.019429	-1.03114	-1.16355	-1.65940	-0.53112	Lesser	-0.31811	4.07e-14
N115	0.099398	0.035849	-1.08405	-0.74832	-1.31833	-0.30894	Lesser	-0.32195	4.07e-14
N39	0.17923	0.079835	-1.00699	-0.92895	-1.30638	-0.55192	Lesser	-0.33042	4.07e-14
N52	0.31761	0.140764	-1.19757	-0.78576	-1.66060	-0.26275	Lesser	-0.33322	4.07e-14
N176	0.020461	0.007616	-2.45666	-1.04309	-6.99072	0.26811	Lesser	-0.33686	4.07e-14
N79	0.019205	0.006579	-1.36587	-1.50646	-3.52001	0.05259	Lesser	-0.34001	4.07e-14
N30	0.041005	0.002028	-1.39567	-1.75396	-4.04740	0.28101	Lesser	-0.34107	4.07e-14
N154	0.022816	0.000605	-1.52055	-2.12146	-3.80305	0.34971	Lesser	-0.34650	4.07e-14
N35	0.027209	0.007957	-1.88648	-1.20005	-2.91557	0.11986	Lesser	-0.34974	4.07e-14
N114	0.031261	0.010492	-1.49506	-1.44543	-3.17243	0.03434	Lesser	-0.35021	4.07e-14
N8	0.004139	0.000132	-1.69238	-3.42356	-4.26046	0.93816	Lesser	-0.35850	4.07e-14
N150	0.042993	0.012122	-1.49654	-1.01383	-2.55345	-0.04350	Lesser	-0.36120	4.07e-14
N120	0.01069	0.003944	-1.36932	-1.87200	-3.25483	-0.36157	Lesser	-0.36315	4.07e-14
N121	0.032532	0.003665	-1.50886	-1.47392	-2.89828	-0.34677	Lesser	-0.37175	4.07e-14
N14	0.038032	0.031927	-1.80650	-2.51348	-3.82293	0.34874	Lesser	-0.37755	4.07e-14
N128	0.12199	0.036426	-1.96033	-0.98157	-4.89894	-0.02261	Lesser	-0.39735	4.07e-14
N130	0.078871	0.00744	-1.63509	-1.67937	-2.68122	-0.80233	Lesser	-0.40925	4.07e-14
N87	0.078835	0.002094	-2.14320	-2.20211	-4.21777	-0.25316	Lesser	-0.41646	4.07e-14
N29	0.067794	0.005059	-1.77525	-2.07774	-3.10707	-0.34735	Lesser	-0.41860	4.07e-14
N46	0.018841	0.004736	-1.62163	-1.66631	-2.54866	-0.77565	Lesser	-0.41864	4.07e-14
N135	0.061006	0.002054	-2.04846	-2.16022	-3.84962	-0.16492	Lesser	-0.41899	4.07e-14
N67	0.033022	0.008004	-1.68914	-1.28851	-2.13222	-0.66417	Lesser	-0.42329	4.07e-14
N185	0.183525	0.039193	-1.67912	-1.25204	-2.74644	-0.69698	Lesser	-0.43379	4.07e-14
N183	0.073561	0.011351	-1.77779	-1.82513	-2.72735	-0.79178	Lesser	-0.43562	4.07e-14
N49	0.157581	0.056396	-1.75854	-1.21698	-2.82122	-0.58456	Lesser	-0.43928	4.07e-14
N84	0.232305	0.020255	-1.87713	-1.96317	-3.08132	-0.62669	Lesser	-0.44354	4.07e-14
N104	0.974196	0.190315	-1.65305	-1.52295	-2.34219	-1.01704	Lesser	-0.44621	4.07e-14
N123	0.030412	0.007357	-1.81817	-1.86656	-2.75005	-0.89760	Lesser	-0.44766	4.07e-14
N116	0.024521	0.002331	-1.81365	-2.00770	-2.56979	-1.22971	Lesser	-0.45363	4.07e-14
N24	0.006238	2e-06	-3.66944	-5.86363	-8.01384	0.00000	Lesser	-0.45590	4.07e-14
N134	0.202424	0.042708	-2.16201	-1.88889	-3.74414	-0.62562	Lesser	-0.45979	4.07e-14
N100	0.032452	0.003224	-1.83630	-1.87952	-2.55699	-1.11001	Lesser	-0.46350	4.07e-14
N146	0.008261	0.003061	-2.36042	-3.47210	-4.61460	-0.34192	Lesser	-0.47530	4.07e-14
N162	0.038629	0.001076	-2.21299	-3.00786	-3.70638	-0.43250	Lesser	-0.48448	4.07e-14
N178	0.443801	0.032299	-1.97616	-1.95407	-2.71952	-1.06555	Lesser	-0.48560	4.07e-14
N40	0.038042	0.001236	-2.12334	-2.12389	-3.69130	-0.92198	Lesser	-0.49026	4.07e-14
N51	0.099886	0.025312	-2.72031	-2.12085	-5.14595	-0.31619	Lesser	-0.49822	4.07e-14
N88	0.083778	0.008366	-2.20901	-2.39014	-3.55401	-1.24356	Lesser	-0.50745	4.07e-14
N50	0.037533	0.001522	-2.30116	-2.65151	-3.30608	-1.36332	Lesser	-0.51850	4.07e-14
N161	0.010205	7.8e-05	-2.78316	-4.50551	-5.19875	-1.51826	Lesser	-0.52487	4.07e-14
N90	0.173879	0.009469	-2.42857	-2.57000	-3.81366	-1.20881	Lesser	-0.54115	4.07e-14
N47	0.191654	0.028218	-2.60307	-2.75718	-3.75539	-1.07944	Lesser	-0.56264	4.07e-14
N184	0.249507	0.012482	-2.65179	-2.63392	-3.16779	-2.12094	Lesser	-0.59917	4.07e-14
N131	0.106794	0.024273	-3.32215	-4.02704	-5.36785	-1.04517	Lesser	-0.63827	4.07e-14
N102	0.183179	0.008187	-2.97871	-3.01728	-3.55663	-2.48504	Lesser	-0.64146	4.07e-14
N61	0.004861	3e-06	-5.28902	-7.56112	-8.17456	0.00000	Lesser	-0.67078	4.07e-14
N41	0.04834	0.000846	-3.30959	-3.76873	-4.26831	-2.54856	Lesser	-0.68311	4.07e-14
N107	0.3887	0.004897	-3.54856	-4.19178	-4.80296	-2.96435	Lesser	-0.69539	4.07e-14
N111	0.072467	0.001719	-3.41918	-3.53951	-3.87610	-3.13713	Lesser	-0.70891	4.07e-14
N125	0.017569	0.000345	-3.48846	-3.68888	-4.22232	-2.78796	Lesser	-0.71482	4.07e-14
N186	0.110453	0.002387	-3.65818	-3.74360	-4.05990	-3.36273	Lesser	-0.74365	4.07e-14
N159	0.079012	0.00066	-4.01968	-4.45786	-4.87945	-2.88773	Lesser	-0.78166	4.07e-14
N2	0.022659	0.000315	-4.05155	-4.16460	-4.61877	-3.65569	Lesser	-0.79481	4.07e-14
N126	0.198724	0.002202	-4.24353	-4.23968	-4.51028	-3.94911	Lesser	-0.82596	4.07e-14
N129	0.152226	0.000232	-6.12150	-6.38769	-6.78819	-5.88796	Lesser	-0.91954	4.07e-14
N37	0.042205	3e-06	-8.90202	-9.68982	-10.07076	-8.68963	Lesser	-0.97014	4.07e-14