Propertites of Heterotachy Phylogeny of MICU1 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N120	2e-06	0.229091	7.50227	4.95500	4.02720	11.44996	Greater	0.91769	3.102e-14
N125	0.008724	0.336284	3.70829	3.68961	3.34606	4.08531	Greater	0.83020	3.102e-14
N74	0.000836	0.152813	4.82752	4.81837	2.90133	5.68945	Greater	0.80485	3.102e-14
N14	3e-06	0.061583	6.31238	8.84894	2.24546	10.10974	Greater	0.74565	3.102e-14
N130	0.029608	0.768116	3.01769	3.05171	2.45319	3.66910	Greater	0.74559	3.102e-14
N70	0.008486	0.169945	4.48123	2.78225	2.19591	9.24102	Greater	0.74109	3.102e-14
N67	3e-06	0.009216	5.90377	7.62087	1.84583	8.77090	Greater	0.72821	3.102e-14
N124	0.001198	0.194087	5.39338	4.49168	2.87545	10.12152	Greater	0.72353	3.102e-14
N122	2e-06	2.2e-05	2.64510	2.39790	1.99243	2.89037	Greater	0.68980	3.102e-14
N23	0.021266	0.267373	2.35289	2.28976	1.95182	2.69623	Greater	0.68683	3.102e-14
N87	0.00299	0.077937	4.70870	3.01201	1.86346	9.73515	Greater	0.68300	3.102e-14
N35	0.008517	0.076655	5.27468	2.36095	1.38957	9.96913	Greater	0.67791	3.102e-14
N78	2e-06	0.000108	4.07263	3.93183	3.20545	6.20658	Greater	0.66468	3.102e-14
N75	0.327105	2.358412	2.10945	2.09348	1.90867	2.28063	Greater	0.65769	3.102e-14
N32	0.004304	0.082504	4.48003	2.38491	1.46010	10.02922	Greater	0.63341	3.102e-14
N109	0.008528	0.160257	2.54890	2.49850	1.59859	3.43471	Greater	0.63268	3.102e-14
N126	0.011308	0.213853	2.17675	2.23733	1.71820	2.74700	Greater	0.63046	3.102e-14
N91	0.030522	0.306218	1.88898	1.83757	1.43403	2.29121	Greater	0.58862	3.102e-14
N135	0.024172	0.220254	2.01488	1.83213	1.29200	2.55161	Greater	0.57965	3.102e-14
N47	0.04293	0.263361	1.86346	1.69203	1.27203	2.33674	Greater	0.56086	3.102e-14
N10	0.014743	0.086079	1.96119	1.86262	1.22774	2.61807	Greater	0.55028	3.102e-14
N27	0.040512	0.235014	1.60656	1.59664	1.27181	1.91691	Greater	0.52912	3.102e-14
N81	0.006009	0.075588	2.95890	2.02468	0.85757	3.42332	Greater	0.50125	3.102e-14
N31	0.004217	0.04635	2.04118	1.81975	1.04367	2.73491	Greater	0.49973	3.102e-14
N86	0.02025	0.11057	1.53903	1.48923	1.03915	1.96085	Greater	0.49093	3.102e-14
N29	0.0218	0.105467	1.52451	1.46599	0.99683	2.03452	Greater	0.48127	3.102e-14
N77	0.045039	0.180982	1.45436	1.25555	0.74863	1.97847	Greater	0.43912	3.102e-14
N133	0.12658	0.586168	1.24945	1.21000	0.99448	1.45135	Greater	0.43324	3.102e-14
N83	0.051121	0.179195	1.27480	1.18890	0.86758	1.58896	Greater	0.42722	3.102e-14
N12	0.005671	0.063387	2.41647	1.95117	0.55715	3.13190	Greater	0.42508	3.102e-14
N21	0.017055	0.077512	1.30099	1.27141	0.61076	1.96081	Greater	0.40423	3.102e-14
N45	0.043	0.18151	1.17242	1.25858	0.73543	1.70089	Greater	0.38979	3.102e-14
N8	0.019899	0.110532	1.17885	1.24673	0.52849	1.79335	Greater	0.37653	3.102e-14
N20	0.013849	0.073414	1.14526	1.19244	0.68485	1.82450	Greater	0.37270	3.102e-14
N30	0.058559	0.188971	1.07812	1.07226	0.69659	1.44896	Greater	0.36960	3.102e-14
N62	0.074347	0.204109	1.13700	1.03260	0.31290	1.88486	Greater	0.33350	3.102e-14
N131	0.04992	0.133606	1.08959	0.90183	0.37388	1.66749	Greater	0.32220	3.102e-14
N66	3e-06	0.00777	1.85847	1.25276	-0.18359	7.18728	Greater	0.30416	3.102e-14
N25	0.023593	0.106619	0.93592	1.07335	0.36224	1.60453	Greater	0.30353	3.102e-14
N95	0.064743	0.180504	0.87017	0.92548	0.54743	1.23956	Greater	0.30024	3.102e-14
N57	0.062085	0.136946	0.89626	0.86522	0.41188	1.36648	Greater	0.29548	3.102e-14
N55	0.132103	0.408048	0.81788	0.82420	0.39229	1.22636	Greater	0.27990	3.102e-14
N59	0.015227	0.063439	0.83905	1.01145	0.18092	1.75504	Greater	0.27731	3.102e-14
N15	0.008738	0.033011	0.75008	0.84331	0.01637	1.50177	Greater	0.24142	3.102e-14
N44	0.174736	0.39842	0.61375	0.60323	0.20876	1.02181	Greater	0.20716	3.102e-14
N50	0.039752	0.121033	0.66848	0.60868	-0.20732	1.46449	Greater	0.19698	3.102e-14
N76	0.004151	0.011961	1.29953	1.05865	-1.85636	3.23973	Greater	0.19420	3.102e-14
N4	0.020273	0.05594	0.57521	0.81342	-0.25876	1.57725	Greater	0.19175	3.102e-14
N26	3e-06	0.015138	1.58661	0.37820	-0.40547	8.22094	Greater	0.18168	3.102e-14
N34	2e-06	0.011228	1.36740	0.40547	-0.49741	8.09239	Greater	0.17204	3.102e-14
N11	0.025245	0.040695	0.41661	0.55928	-0.29513	1.21334	Greater	0.14421	3.102e-14
N61	0.046681	0.094825	0.39828	0.45470	-0.50701	1.43390	Greater	0.12844	1.6077e-12
N18	0.049979	0.091626	0.36078	0.39095	-0.04788	0.80291	Greater	0.11716	3.6882e-11
N137	0.118486	0.17821	0.35976	0.38277	0.02146	0.73150	Greater	0.11688	3.0212e-11
N104	0.050701	0.204757	0.07428	0.57053	-0.77357	1.39528	Greater	0.10381	8.35e-09
N40	0.04386	0.095595	0.25340	0.37412	-0.17351	0.80342	Greater	0.08624	2.6304e-06
N13	0.069957	0.11386	0.20714	0.39583	-0.35383	0.96207	Greater	0.08545	6.7704e-06
N69	2e-06	0.004358	0.34363	0.40547	-8.07734	2.56437	Greater	0.08279	6.7704e-06
N129	3e-06	0.000159	0.34874	0.00000	-3.79852	4.38203	Greater	0.06944	0.0002709
N92	0.132151	0.233664	0.22878	0.24561	-0.06989	0.52928	Greater	0.06526	0.00070352
N107	0.094927	0.150542	0.19826	0.28626	-0.24289	0.72197	Greater	0.06351	0.0009478
N132	0.001509	0.0003	0.21669	0.00000	-3.96172	4.16667	Greater	0.04020	0.102063
N102	0.914059	1.139539	0.15645	0.15470	-0.23560	0.49213	Greater	0.03687	0.16032
N72	0.004879	0.00318	0.12139	0.16796	-3.68032	2.70918	Greater	0.03184	0.30646
N99	0.01811	0.018422	0.18110	0.05704	-1.51891	1.36725	Greater	0.02899	0.418
N101	0.062692	0.382784	-1.41868	0.88560	-9.59649	2.12478	Greater	0.02859	0.418
N49	0.148305	0.263739	0.07478	0.22601	-0.23090	0.54833	Greater	0.02318	0.6544
N117	0.086986	0.142054	0.02692	0.11428	-0.55525	0.74164	Greater	0.01989	0.7116
N22	0.009609	0.000629	-0.06101	0.09108	-6.16176	2.12026	Greater	0.01704	0.7116
N38	0.062266	0.075526	0.04776	0.11620	-0.35064	0.52316	Greater	0.00789	0.9588
N64	0.581402	0.612754	0.06441	0.04068	-0.28633	0.37753	Greater	0.00084	0.9588
N119	0.209703	0.252984	0.04035	0.01969	-0.29232	0.34984	Lesser	-0.00604	0.9588
N84	0.00664	0.001365	0.18398	-0.68947	-3.67268	3.71357	Lesser	-0.01788	0.7116
N54	0.068226	0.101967	-0.16405	0.04498	-0.76702	0.70934	Lesser	-0.02298	0.6544
N100	0.134232	0.175993	-0.16393	-0.17121	-0.71497	0.41169	Lesser	-0.06502	0.00070352
N139	0.021034	0.026375	-0.37770	-0.32935	-1.70289	0.91778	Lesser	-0.06987	0.00037774
N140	0.3523	0.371332	-0.17356	-0.16466	-0.51266	0.20777	Lesser	-0.08332	6.0742e-06
N88	0.02572	0.03707	-0.36358	-0.19126	-0.92384	0.48123	Lesser	-0.08379	1.21144e-05
N51	0.160109	0.167688	-0.23780	-0.18026	-0.61323	0.25424	Lesser	-0.08683	3.0199e-06
N7	0.019463	0.009964	-1.37974	-0.00679	-2.61129	0.89360	Lesser	-0.11482	6.7704e-11
N94	0.087474	0.103365	-0.34388	-0.25612	-0.83111	0.20862	Lesser	-0.12012	1.31602e-11
N114	0.065301	0.058462	-0.56534	-0.39691	-1.17478	0.34629	Lesser	-0.13422	1.98586e-13
N110	0.013181	0.000723	-0.73939	-1.90595	-3.38285	1.20971	Lesser	-0.15573	3.102e-14
N33	0.012978	0.015092	-1.05713	-0.79812	-5.00335	1.02840	Lesser	-0.15657	3.102e-14
N128	0.010419	0.000117	-1.13038	-0.94516	-4.96456	1.07921	Lesser	-0.15662	3.102e-14
N19	0.00942	0.012316	-1.45013	-0.29643	-1.97452	0.56237	Lesser	-0.17011	3.102e-14
N112	0.227419	0.146576	-0.49802	-0.49472	-0.98143	0.02478	Lesser	-0.17021	3.102e-14
N68	0.017092	0.000602	-1.44570	-0.63124	-5.34782	0.90765	Lesser	-0.17873	3.102e-14
N37	0.009468	6.3e-05	-1.75637	-0.83887	-5.96422	1.27123	Lesser	-0.17937	3.102e-14
N48	0.0502	0.041537	-1.06360	-0.46605	-1.81042	0.42817	Lesser	-0.18066	3.102e-14
N39	0.015081	0.006472	-1.30843	-0.52388	-2.82204	0.47269	Lesser	-0.18943	3.102e-14
N90	0.05852	0.033093	-0.94692	-0.43696	-1.70662	0.21907	Lesser	-0.20121	3.102e-14
N98	0.303803	0.061782	-0.62662	-0.66543	-1.24149	-0.07765	Lesser	-0.20521	3.102e-14
N123	0.012651	2.1e-05	-2.21635	-0.55063	-6.69595	1.08924	Lesser	-0.20936	3.102e-14
N136	0.060314	0.032143	-0.92883	-0.76645	-1.64484	0.04092	Lesser	-0.21257	3.102e-14
N82	0.112966	0.089448	-0.66992	-0.58872	-1.14436	-0.17080	Lesser	-0.23873	3.102e-14
N141	0.051434	0.037119	-1.78890	-0.98409	-3.32839	0.47221	Lesser	-0.24129	3.102e-14
N46	0.141673	0.103713	-1.19874	-0.72449	-2.16507	0.07825	Lesser	-0.25448	3.102e-14
N63	0.248178	0.204443	-0.89225	-0.76474	-1.46079	-0.16085	Lesser	-0.26025	3.102e-14
N9	0.041229	0.0266	-0.93378	-0.88340	-1.66449	-0.08045	Lesser	-0.26063	3.102e-14
N80	0.145252	0.096625	-0.77414	-0.68500	-1.09522	-0.36465	Lesser	-0.27323	3.102e-14
N43	0.239804	0.156045	-0.77921	-0.70244	-1.03497	-0.38974	Lesser	-0.27544	3.102e-14
N2	0.017443	0.010378	-1.79135	-0.99054	-4.91741	0.26425	Lesser	-0.27749	3.102e-14
N65	0.035354	0.015289	-1.91388	-1.07028	-5.08892	0.38081	Lesser	-0.28244	3.102e-14
N93	0.098011	0.04099	-1.06862	-0.71939	-1.67006	-0.21492	Lesser	-0.28425	3.102e-14
N52	0.254227	0.104071	-0.94668	-0.93038	-1.45179	-0.42583	Lesser	-0.28728	3.102e-14
N115	0.080885	0.032326	-1.44784	-1.11474	-2.57359	-0.10199	Lesser	-0.30706	3.102e-14
N17	0.009146	3.5e-05	-2.78808	-0.67701	-8.62909	0.00000	Lesser	-0.32737	3.102e-14
N138	0.138409	0.075738	-1.28746	-1.04005	-1.96909	-0.45517	Lesser	-0.33866	3.102e-14
N96	1.255602	0.555276	-1.07638	-0.98267	-1.37707	-0.64378	Lesser	-0.34982	3.102e-14
N53	0.444179	0.144018	-1.61230	-1.44009	-2.30117	-0.79798	Lesser	-0.41643	3.102e-14
N24	0.0112	2e-05	-3.61809	-5.88404	-7.38432	0.06401	Lesser	-0.41796	3.102e-14
N56	0.069589	0.001961	-2.36146	-1.88869	-4.45214	-0.47741	Lesser	-0.42048	3.102e-14
N6	0.003877	3e-06	-3.57105	0.00000	-7.44736	0.00000	Lesser	-0.42304	3.102e-14
N79	0.044392	0.014683	-2.37619	-2.11992	-3.68232	-0.78449	Lesser	-0.44632	3.102e-14
N85	0.016625	0.009102	-2.15376	-1.80154	-3.42189	-0.91932	Lesser	-0.45571	3.102e-14
N116	0.019287	0.002651	-2.48102	-2.97195	-4.26657	-1.34856	Lesser	-0.46617	3.102e-14
N73	0.000586	2e-06	-4.05460	-0.69315	-8.72144	0.00000	Lesser	-0.46819	3.102e-14
N113	0.069249	0.002492	-3.37279	-4.27482	-6.95351	-1.85688	Lesser	-0.47304	3.102e-14
N118	0.061611	0.008166	-2.22576	-1.84374	-2.73325	-1.18221	Lesser	-0.49634	3.102e-14
N103	0.244756	0.001234	-3.06027	-3.26353	-5.14995	-1.11780	Lesser	-0.49649	3.102e-14
N58	0.276708	0.065965	-2.82291	-2.06225	-5.22427	-0.79709	Lesser	-0.49852	3.102e-14
N28	0.031339	0.002246	-4.04557	-2.27066	-8.99386	-0.43125	Lesser	-0.50202	3.102e-14
N97	0.050551	0.02109	-2.53444	-2.17559	-3.65435	-1.21620	Lesser	-0.51069	3.102e-14
N60	0.166882	0.035324	-2.22350	-2.05468	-2.72075	-1.32994	Lesser	-0.51086	3.102e-14
N5	0.020282	0.004308	-4.63943	-7.95238	-9.17425	-0.45798	Lesser	-0.53743	3.102e-14
N108	0.032099	0.000143	-3.66161	-4.33039	-6.17702	-2.15868	Lesser	-0.54896	3.102e-14
N1	0.045681	0.000665	-4.57928	-6.45256	-7.10950	-0.66680	Lesser	-0.55570	3.102e-14
N71	0.011885	3e-06	-4.69039	-7.53128	-8.72851	-0.52558	Lesser	-0.55869	3.102e-14
N111	0.33106	0.025126	-2.64563	-2.27495	-3.38356	-1.54553	Lesser	-0.55993	3.102e-14
N105	0.70327	0.056799	-2.77230	-2.70664	-3.42857	-1.81569	Lesser	-0.56859	3.102e-14
N89	0.051448	0.003325	-3.08066	-2.74985	-4.84856	-1.93857	Lesser	-0.57631	3.102e-14
N3	0.077466	3e-06	-5.26185	-3.30067	-10.40738	-0.57908	Lesser	-0.58897	3.102e-14
N42	0.024013	7.1e-05	-4.64044	-5.17449	-6.14053	-3.57488	Lesser	-0.69091	3.102e-14
N121	0.012621	3.3e-05	-5.05630	-5.71109	-6.37465	-4.29521	Lesser	-0.71030	3.102e-14
N36	0.025011	3.9e-05	-5.66169	-6.52719	-7.23089	-5.09789	Lesser	-0.72498	3.102e-14
N106	0.147496	0.000992	-4.77033	-4.87042	-5.58850	-4.11315	Lesser	-0.73097	3.102e-14
N16	0.023074	4.4e-05	-7.20482	-8.85381	-9.29040	-6.63857	Lesser	-0.78876	3.102e-14
N41	0.093784	0.000122	-6.17469	-6.53613	-7.01868	-5.82162	Lesser	-0.80095	3.102e-14
N127	0.071467	7.1e-05	-6.08836	-6.66720	-7.19128	-4.97384	Lesser	-0.80950	3.102e-14
N134	0.102378	0.000282	-6.79550	-5.92163	-10.17243	-4.77320	Lesser	-0.82574	3.102e-14