Propertites of Heterotachy Phylogeny of SHMT2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N25	3e-06	0.009628	8.14292	8.22613	7.68891	8.61480	Greater	0.93059	2.53e-14
N97	0.021604	2.359687	5.00667	4.89184	4.61271	5.30217	Greater	0.86599	2.53e-14
N80	0.040547	2.183212	4.11871	4.06459	3.76227	4.43535	Greater	0.83006	2.53e-14
N104	0.00285	0.046044	5.94401	3.27690	2.17686	10.17292	Greater	0.81066	2.53e-14
N74	0.034249	0.018775	3.99072	4.19113	3.63057	4.66408	Greater	0.79216	2.53e-14
N7	0.14211	3.216892	3.36283	3.24487	2.81629	3.78289	Greater	0.76609	2.53e-14
N67	0.130397	2.656638	3.20972	3.18707	2.82078	3.58563	Greater	0.76412	2.53e-14
N9	0.019532	0.30021	2.96938	2.86588	2.49828	3.40797	Greater	0.73845	2.53e-14
N102	2e-06	0.00028	5.24011	5.74140	2.92674	8.28841	Greater	0.73589	2.53e-14
N94	0.012195	0.277829	2.73105	2.70274	2.05832	3.30548	Greater	0.70964	2.53e-14
N95	2e-06	0.011735	5.56924	7.20971	1.64195	9.50036	Greater	0.70691	2.53e-14
N3	0.036379	0.37332	2.49448	2.49417	1.96147	3.03035	Greater	0.68569	2.53e-14
N96	2e-06	0.000268	4.53356	6.42271	3.53612	6.82111	Greater	0.66440	2.53e-14
N10	0.013711	0.108047	2.28547	2.16721	1.69450	2.76427	Greater	0.65683	2.53e-14
N99	0.001854	0.013285	4.34259	2.59531	1.33446	8.89059	Greater	0.62914	2.53e-14
N6	0.221103	2.615605	2.27993	2.50733	1.96457	2.96178	Greater	0.62407	2.53e-14
N35	0.009964	0.025319	3.47596	2.32573	1.16186	3.97655	Greater	0.61992	2.53e-14
N103	1e-06	0.013305	4.17508	2.06385	1.06689	9.62971	Greater	0.60149	2.53e-14
N8	0.002552	0.100698	3.32313	1.79389	0.60631	4.44589	Greater	0.58283	2.53e-14
N18	0.012903	0.065928	1.58907	1.54191	1.17213	1.96542	Greater	0.56775	2.53e-14
N11	0.016895	0.057127	1.61408	1.60486	1.08601	2.09989	Greater	0.56139	2.53e-14
N65	0.178371	0.759104	1.49569	1.46504	1.08710	1.94754	Greater	0.54234	2.53e-14
N107	0.004143	0.00895	2.78193	1.72516	0.61902	4.95112	Greater	0.51568	2.53e-14
N76	0.040757	0.116283	1.18830	1.15784	0.85861	1.49270	Greater	0.50055	2.53e-14
N112	0.142224	0.108708	1.70303	2.54089	-0.02191	2.90239	Greater	0.47139	2.53e-14
N109	0.03577	0.035576	2.14255	1.01176	0.16943	3.22986	Greater	0.44931	2.53e-14
N20	2e-06	0.00747	2.66548	0.40547	0.40547	8.56303	Greater	0.42361	2.53e-14
N105	0.078023	0.155708	1.16984	0.69235	0.21220	2.26524	Greater	0.38226	2.53e-14
N12	0.121027	0.220417	0.52011	0.54456	0.27905	0.78785	Greater	0.33405	2.53e-14
N77	0.005713	0.027383	0.78057	1.00114	0.02706	1.75538	Greater	0.32762	2.53e-14
N79	0.003895	0.002184	2.26599	1.82392	-1.04012	6.99805	Greater	0.32376	2.53e-14
N4	2e-06	0.081948	1.98856	0.69315	0.00000	8.81180	Greater	0.32071	2.53e-14
N13	0.043921	0.065869	0.47758	0.54671	0.13449	0.87018	Greater	0.30858	2.53e-14
N5	0.121848	0.355713	0.51562	0.63554	0.11097	1.03602	Greater	0.30121	2.53e-14
N108	0.008392	0.038643	0.78440	0.69648	-0.31244	1.91340	Greater	0.28661	2.53e-14
N16	0.030661	0.037442	0.40427	0.34850	-0.07507	0.81323	Greater	0.26631	2.53e-14
N40	0.01229	0.017151	0.39196	0.36146	-0.13972	0.92237	Greater	0.25686	2.53e-14
N54	0.016946	0.024037	0.33814	0.37402	-0.11372	0.85915	Greater	0.24947	2.53e-14
N69	0.046263	0.049342	0.28618	0.28930	-0.26299	0.84649	Greater	0.21638	2.53e-14
N87	0.036179	0.028313	0.16912	0.22778	-0.35654	0.79692	Greater	0.18605	2.53e-14
N88	0.056476	0.056425	0.13029	0.09535	-0.31396	0.55747	Greater	0.17204	2.53e-14
N92	0.080137	2.012834	0.29881	-0.11850	-0.57356	0.56004	Greater	0.15170	2.53e-14
N86	0.02604	0.016875	-0.03038	-0.02026	-0.67002	0.67524	Greater	0.10803	6.8666e-09
N56	0.015292	0.014527	0.02051	-0.07887	-0.64203	0.50231	Greater	0.10541	2.1862e-07
N82	0.011751	0.014828	-0.01754	-0.13129	-0.73524	0.75569	Greater	0.10174	7.1136e-08
N93	3e-06	3e-06	-0.84730	0.40547	-5.58224	0.40547	Greater	0.07104	0.00011492
N84	0.087429	0.057845	-0.17542	-0.19233	-0.45766	0.09061	Greater	0.06839	0.00022077
N110	0.025477	0.046852	-1.13965	0.22275	-2.56321	1.66102	Greater	0.05414	0.00575
N98	0.016639	0.01618	-0.34772	0.20011	-2.64426	1.28777	Greater	0.04438	0.031824
N101	0.031733	0.026437	-0.24143	-0.18638	-0.68795	0.22953	Greater	0.04398	0.031824
N60	0.023666	0.012441	-0.25565	-0.22195	-0.79777	0.33105	Greater	0.03823	0.0591
N50	0.040411	0.020229	-0.31953	-0.27884	-0.72844	0.15360	Greater	0.01390	0.4086
N73	0.094798	0.098	-0.47360	-0.12292	-0.85295	0.35289	Greater	0.01301	0.4086
N78	0.052845	0.040962	-0.41022	-0.51313	-0.79995	-0.07333	Lesser	-0.03187	0.08346
N75	0.097279	0.070573	-0.49704	-0.34623	-1.30238	0.31912	Lesser	-0.03769	0.0591
N64	0.061117	0.036314	-0.51233	-0.54906	-1.32109	0.38769	Lesser	-0.04456	0.031824
N85	0.014689	0.010448	-0.56582	-0.44901	-1.03339	0.14463	Lesser	-0.04532	0.031824
N106	0.09649	0.059472	-0.52964	-0.64711	-1.13601	0.05131	Lesser	-0.07441	5.5314e-05
N116	0.096195	0.029214	-0.72962	-0.31294	-1.59804	0.15787	Lesser	-0.07527	0.00011492
N100	0.042337	0.065075	-0.72026	-0.68379	-1.19488	0.17889	Lesser	-0.08839	8.349e-07
N27	0.002734	3e-06	-2.43531	0.40547	-7.36750	0.40547	Lesser	-0.10538	2.002e-09
N45	0.012746	0.010153	-0.77474	-0.75178	-1.36435	0.01596	Lesser	-0.10540	7.944e-07
N32	0.007289	0.004952	-1.72795	-0.52569	-7.63119	0.36626	Lesser	-0.11109	2.8094e-10
N68	0.22915	0.116929	-0.62776	-0.64113	-0.99302	-0.25629	Lesser	-0.11239	1.72017e-10
N59	0.030973	0.014134	-0.85702	-0.75123	-1.43085	0.01045	Lesser	-0.11495	7.4025e-10
N42	0.018179	0.008515	-1.96814	-0.53683	-7.24232	0.50154	Lesser	-0.11536	5.1696e-11
N72	0.351944	0.183893	-0.62546	-0.62249	-0.83533	-0.40603	Lesser	-0.11961	8.5825e-12
N51	0.053658	0.023932	-0.70987	-0.67972	-1.12127	-0.23559	Lesser	-0.12682	6.0528e-13
N113	0.02621	0.017024	-1.30816	-0.50605	-2.69604	-0.12285	Lesser	-0.14633	2.53e-14
N115	0.0651	0.041443	-0.92327	-1.13472	-1.86109	0.00080	Lesser	-0.17072	2.53e-14
N33	0.008589	2e-06	-2.35609	-0.40547	-8.52595	0.00000	Lesser	-0.18090	2.53e-14
N114	0.114522	1.38288	-1.00968	-1.15975	-1.90499	-0.51918	Lesser	-0.19168	2.53e-14
N57	0.006704	0.004015	-2.47399	-1.10869	-7.51425	0.36135	Lesser	-0.20513	2.53e-14
N49	0.009974	0.00601	-2.68840	-0.80058	-7.85671	0.23973	Lesser	-0.21066	2.53e-14
N48	0.099383	0.045557	-0.91027	-0.85810	-1.26169	-0.51415	Lesser	-0.21443	2.53e-14
N70	0.063804	0.037253	-1.16746	-0.86371	-1.65912	-0.29435	Lesser	-0.21469	2.53e-14
N17	0.028305	0.008382	-0.91586	-0.91170	-1.34122	-0.52584	Lesser	-0.21735	2.53e-14
N117	0.012044	0.005124	-2.27079	-1.02502	-7.37044	-0.00741	Lesser	-0.23346	2.53e-14
N31	0.056999	0.022282	-1.00433	-0.94243	-1.34909	-0.57717	Lesser	-0.24072	2.53e-14
N111	0.085379	0.027172	-1.59842	-0.78625	-2.72691	-0.41431	Lesser	-0.27157	2.53e-14
N91	0.067977	0.009892	-1.25395	-1.20567	-1.88090	-0.59214	Lesser	-0.28369	2.53e-14
N58	0.07728	0.014492	-1.23274	-1.13301	-1.62818	-0.68586	Lesser	-0.29328	2.53e-14
N52	0.049823	0.010228	-1.37035	-1.21862	-1.82405	-0.67654	Lesser	-0.30391	2.53e-14
N55	0.033847	0.006206	-2.59070	-1.18218	-3.49001	-0.31981	Lesser	-0.30932	2.53e-14
N90	0.126437	0.035608	-1.21114	-1.16988	-1.61059	-0.79093	Lesser	-0.31066	2.53e-14
N53	0.040836	0.007155	-1.51027	-1.46901	-2.18630	-0.77136	Lesser	-0.32945	2.53e-14
N39	0.018094	0.005041	-3.60394	-1.24221	-8.62089	-0.19829	Lesser	-0.33248	2.53e-14
N71	0.168188	0.047295	-1.38610	-1.23382	-1.83421	-0.79889	Lesser	-0.33259	2.53e-14
N34	3e-06	2e-06	-4.12310	-7.24637	-7.89450	0.00000	Lesser	-0.34995	2.53e-14
N63	0.021606	0.005976	-3.51919	-1.17481	-8.79354	-0.40547	Lesser	-0.35908	2.53e-14
N36	0.01309	3e-06	-4.01910	-2.64362	-8.79664	-0.33350	Lesser	-0.37889	2.53e-14
N89	0.059049	0.012713	-1.53187	-1.40918	-1.95016	-0.98575	Lesser	-0.37893	2.53e-14
N61	0.102822	0.016159	-1.53613	-1.47661	-1.87755	-1.13859	Lesser	-0.40290	2.53e-14
N21	0.002325	2e-06	-4.38527	-6.97073	-7.85941	-0.40547	Lesser	-0.41902	2.53e-14
N38	0.01649	0.004624	-4.05770	-1.44727	-8.96233	-0.55353	Lesser	-0.42168	2.53e-14
N66	0.412825	0.012733	-2.22175	-1.64718	-3.17151	-1.38470	Lesser	-0.49448	2.53e-14
N15	0.023447	0.004209	-4.14909	-1.86897	-9.22049	-0.92457	Lesser	-0.49500	2.53e-14
N43	0.038653	0.003748	-3.47401	-2.38452	-4.60592	-1.33986	Lesser	-0.50602	2.53e-14
N2	0.095663	0.011043	-2.08924	-2.02604	-2.46717	-1.63241	Lesser	-0.51438	2.53e-14
N30	0.013549	3e-06	-5.79068	-8.23814	-9.09571	-0.95230	Lesser	-0.54376	2.53e-14
N24	0.020176	2e-06	-4.87931	-2.75855	-9.30747	-1.22641	Lesser	-0.54847	2.53e-14
N1	0.023125	0.000795	-3.94250	-3.00233	-7.85147	-1.31470	Lesser	-0.55245	2.53e-14
N81	0.03035	0.000517	-5.47460	-7.76430	-9.57772	-0.96798	Lesser	-0.55980	2.53e-14
N22	0.017341	3e-06	-5.65496	-7.85425	-9.01696	-1.66718	Lesser	-0.58057	2.53e-14
N83	0.058683	0.005814	-4.52057	-2.77398	-9.58768	-1.54165	Lesser	-0.61136	2.53e-14
N62	0.017973	3e-06	-5.52656	-3.38727	-9.05672	-2.42238	Lesser	-0.69456	2.53e-14
N44	0.08501	0.00522	-5.50073	-3.05050	-10.55060	-2.22883	Lesser	-0.72391	2.53e-14
N47	0.022704	0.000388	-5.51528	-4.28960	-8.57004	-3.82117	Lesser	-0.73395	2.53e-14
N41	0.036915	3e-06	-6.54591	-9.22260	-9.78850	-2.47831	Lesser	-0.76700	2.53e-14
N28	0.039005	3e-06	-6.82688	-8.12726	-9.70747	-4.10051	Lesser	-0.76739	2.53e-14
N37	0.008417	3e-06	-8.16086	-8.20749	-8.48790	-7.83043	Lesser	-0.78175	2.53e-14
N46	0.119531	3e-06	-7.27447	-10.42712	-11.02037	-3.16715	Lesser	-0.82573	2.53e-14
N26	0.026016	2e-06	-8.97912	-9.07004	-9.35535	-8.77158	Lesser	-0.85773	2.53e-14
N29	0.030035	2e-06	-9.67664	-9.70110	-10.12274	-9.40454	Lesser	-0.92447	2.53e-14
N19	0.075629	2e-06	-10.52301	-10.56975	-10.77294	-10.33987	Lesser	-0.98111	2.53e-14