Propertites of Site partitioning Phylogeny of ACO2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N17	0.0074770894	0.4450928459	4.80985	4.65625	3.92632	5.54041	Greater	0.78722	2.794e-14
N15	0.0010450395	0.027367708	6.29671	7.90064	2.85888	8.88637	Greater	0.77570	2.794e-14
N92	0.0039592218	0.2799179817	5.76913	5.02230	4.11387	7.04458	Greater	0.77194	2.794e-14
N35	0.0065487231	0.5676830345	4.53056	4.77546	4.01896	5.33516	Greater	0.75991	2.794e-14
N22	0.0039483764	0.4898910813	5.12921	5.15882	3.86804	6.17536	Greater	0.73718	2.794e-14
N37	0.0026311298	0.0621638126	4.48408	3.27630	2.35562	5.67900	Greater	0.65452	2.794e-14
N76	0.0003246767	0.0450712185	4.95059	3.82129	2.70338	9.28895	Greater	0.65182	2.794e-14
N19	2.9026e-06	0.0102277628	5.39695	5.83181	1.66665	8.66120	Greater	0.64555	2.794e-14
N44	0.1971263439	5.2660778842	3.17964	3.19286	2.53444	3.90838	Greater	0.62364	2.794e-14
N111	2.7548e-06	0.0533592997	6.26068	8.78955	1.04156	9.60743	Greater	0.61630	2.794e-14
N13	0.0130947368	0.1493185473	3.00360	2.80037	2.33475	3.51633	Greater	0.59973	2.794e-14
N18	0.0059877637	0.0698632246	2.93736	2.65652	2.12752	3.59337	Greater	0.58243	2.794e-14
N113	0.0006615265	0.109477955	5.48369	5.58746	0.96075	11.02719	Greater	0.58214	2.794e-14
N23	0.0043631191	0.0404164096	3.99110	3.20094	1.54564	5.05553	Greater	0.58166	2.794e-14
N109	0.0148192162	0.7343591669	3.44989	3.65640	1.86950	5.02770	Greater	0.57159	2.794e-14
N36	0.0101450499	0.3391812637	3.12079	3.28190	1.42389	4.64934	Greater	0.53942	2.794e-14
N117	2.6411e-06	0.0088274046	5.02377	6.95127	0.54488	8.93933	Greater	0.53768	2.794e-14
N115	2.7741e-06	0.0238726863	4.66572	7.57739	0.02756	8.95157	Greater	0.46696	2.794e-14
N77	0.014766689	0.1214904268	2.41805	2.54888	1.26490	3.64610	Greater	0.46016	2.794e-14
N47	0.0576657917	0.353111607	2.18602	1.94033	1.49779	2.46726	Greater	0.45006	2.794e-14
N88	0.2671867655	1.3564245262	2.02489	1.89101	1.31709	2.85405	Greater	0.41841	2.794e-14
N42	0.0633107918	0.2622794606	2.25384	1.97209	0.95794	3.43311	Greater	0.40943	2.794e-14
N124	0.0061978781	0.084497037	2.84865	1.98060	0.63693	3.30740	Greater	0.39041	2.794e-14
N14	0.0024780917	0.0195829255	2.89821	2.08385	0.43258	6.85290	Greater	0.36834	2.794e-14
N54	0.0849602469	0.5701619779	3.91153	2.24204	0.25117	12.44394	Greater	0.35344	2.794e-14
N49	0.1231310294	3.2249051279	1.98518	3.07167	-0.86969	4.43617	Greater	0.33318	2.794e-14
N34	0.2194512345	1.2111746069	1.80754	1.48028	0.59833	2.92177	Greater	0.32537	2.794e-14
N112	0.0044152886	0.1767328034	2.94551	2.45198	-0.38395	7.10946	Greater	0.32330	2.794e-14
N48	0.1810337102	1.1111005975	1.65454	1.52563	0.65763	3.10482	Greater	0.31154	2.794e-14
N16	0.0049583828	0.0195372594	2.33223	1.12317	0.13749	4.81309	Greater	0.30409	2.794e-14
N27	0.0406018784	0.4459345081	1.75078	2.16599	-0.18126	3.84743	Greater	0.29449	2.794e-14
N99	0.0232531923	0.095403145	1.41941	1.56292	0.34310	2.52685	Greater	0.26928	2.794e-14
N119	0.0442229151	0.2098892367	1.25443	1.45159	0.76781	1.96868	Greater	0.25776	2.794e-14
N43	1.141362185	2.8618538448	1.28721	1.22914	0.37271	2.20083	Greater	0.24314	2.794e-14
N4	0.0296373833	0.0493210773	1.40042	1.32622	-0.07386	3.03575	Greater	0.24174	2.794e-14
N105	0.1621042423	0.1446749738	1.78649	1.48883	-1.11134	4.39933	Greater	0.21721	2.794e-14
N101	0.0128170645	0.1499886434	0.98123	1.26861	-0.18354	3.78427	Greater	0.21127	2.794e-14
N10	0.0068509884	0.0312508756	1.09342	1.18869	-0.26492	2.80211	Greater	0.18216	2.794e-14
N79	0.0138349167	0.0529157069	0.91415	1.16638	0.43602	1.73899	Greater	0.18007	2.794e-14
N2	0.0099697753	0.0228727792	0.97963	1.04683	0.09122	1.82888	Greater	0.17239	2.794e-14
N114	0.0014540021	0.013700738	1.31116	0.83161	-1.20334	5.33516	Greater	0.16907	2.794e-14
N1	0.0175307902	0.0465144383	0.97172	0.77319	-0.46525	3.52476	Greater	0.15667	2.794e-14
N75	0.0246635171	0.092748283	0.78660	1.08847	-0.36818	2.34659	Greater	0.15133	2.794e-14
N73	0.0197648022	0.0620367957	0.45068	1.16797	-0.70726	2.77405	Greater	0.13195	4.0774e-14
N80	0.0208547471	0.0558333076	0.73129	0.87250	0.26543	1.36033	Greater	0.12904	3.0233e-13
N87	1.5730167092	6.0182549045	0.75926	0.66965	0.16919	1.42343	Greater	0.12619	5.7324e-13
N24	0.0350814957	0.1184706778	0.65754	1.12537	-0.45993	1.58380	Greater	0.11302	1.77216e-10
N11	0.0072683533	0.0244559514	1.10453	0.62578	-1.51504	2.59593	Greater	0.10413	6.0574e-09
N28	0.0570250665	0.0789272931	0.70181	0.38388	-0.14671	1.74887	Greater	0.09428	1.97856e-07
N12	0.0026649541	0.0110054765	0.29656	0.86594	-1.15980	1.99656	Greater	0.07109	0.000262
N118	0.0258025766	0.0883551477	0.38368	0.64892	-0.45518	1.70205	Greater	0.06969	0.00068517
N120	0.0078940345	0.0147715625	0.30665	0.43607	-1.88396	3.37579	Greater	0.06926	0.00037872
N6	0.012393466	0.0117551289	0.86814	0.28150	-1.03464	2.12137	Greater	0.06085	0.002698
N104	0.0448621625	0.1703394044	0.42174	0.47284	-1.27364	2.18433	Greater	0.05433	0.010412
N98	0.016696659	0.0530174017	0.36611	0.43206	-0.77099	1.92296	Greater	0.05163	0.01782
N29	0.0534075717	0.0709379719	0.47590	0.37771	0.10618	0.65326	Greater	0.04171	0.129472
N38	0.0333920608	0.0524119329	0.42678	0.34096	-0.79314	1.63223	Greater	0.04094	0.118048
N116	0.0001901588	2.3468e-06	0.49618	0.31544	-3.46381	3.67425	Greater	0.03941	0.134025
N20	0.0062756842	0.0144947564	0.26472	0.61701	-0.39260	1.36595	Greater	0.03427	0.25662
N126	0.0768389215	0.1868015831	0.29894	0.54223	-0.55004	1.33776	Greater	0.02682	0.50608
N7	0.0315304572	0.0421314578	0.39752	0.37242	0.05175	0.71821	Greater	0.02393	0.52654
N83	0.0202156965	0.0470536259	-0.08301	0.56136	-1.52093	1.61159	Greater	0.00190	1
N9	0.0200008575	0.0430003207	-0.01974	0.53079	-0.75941	1.29112	Lesser	-0.00208	1
N110	0.0118458832	0.0112061585	0.29143	-0.04754	-2.36081	2.67999	Lesser	-0.00313	1
N45	0.0508816561	0.0864925266	0.19532	0.30315	-0.66382	1.18160	Lesser	-0.00418	1
N72	0.0502740138	0.1751181857	-0.07212	-0.11601	-1.71917	2.46364	Lesser	-0.00582	1
N31	0.2500877246	0.4442412191	0.10596	0.09269	-1.14793	1.55189	Lesser	-0.01646	0.9678
N5	0.0041375599	0.0046680874	-0.35088	0.21145	-3.70598	1.92487	Lesser	-0.03035	0.3121
N30	0.0372044047	0.0356543666	-0.06235	0.11463	-1.95168	1.32361	Lesser	-0.03101	0.3121
N68	0.0012098383	2.9281e-06	-0.29222	0.28411	-5.58060	4.26043	Lesser	-0.03241	0.28303
N121	0.0403576331	0.1913420912	-0.13439	0.27017	-1.22057	1.38519	Lesser	-0.03364	0.26916
N123	0.1452910765	0.2298865692	0.02414	0.16803	-0.80105	1.07477	Lesser	-0.03873	0.139692
N82	0.027773747	0.0475857251	-0.30079	0.27287	-1.37598	1.10813	Lesser	-0.06343	0.00154203
N90	0.0149162078	0.0833969544	-0.95284	0.18015	-2.34612	2.17812	Lesser	-0.06652	0.00070422
N40	0.0516041608	0.0857499238	-0.09145	-0.07838	-0.81386	0.65859	Lesser	-0.08939	1.01218e-06
N97	0.0081238428	0.000901888	-2.02497	-0.07431	-7.55829	3.36839	Lesser	-0.09632	9.9652e-08
N39	0.0988175886	0.0959665239	-0.16674	-0.01305	-1.21857	0.61677	Lesser	-0.09793	5.7826e-08
N95	0.0149515548	0.025931728	-0.87059	0.03200	-1.36213	1.34670	Lesser	-0.10281	9.768e-09
N8	0.0538256783	0.0460157167	-0.14574	-0.07684	-0.60797	0.35933	Lesser	-0.12272	2.71788e-12
N85	0.0333292289	0.0159515445	-0.83654	-0.71113	-2.56333	1.42335	Lesser	-0.12938	1.37556e-13
N25	0.0317199624	0.0194949754	-0.36867	-0.27180	-1.29868	0.61298	Lesser	-0.13346	2.794e-14
N62	0.0018625739	0.0015502606	-0.93909	-0.28854	-6.14885	0.67822	Lesser	-0.13595	2.794e-14
N102	0.0309487365	0.0417547186	-0.55090	-0.27092	-1.78116	0.78674	Lesser	-0.14423	2.794e-14
N86	0.055819905	0.104126748	-0.65803	-0.46171	-1.76334	0.78563	Lesser	-0.15819	2.794e-14
N21	0.0299029321	0.0270575356	-0.29648	-0.23649	-0.61892	0.11393	Lesser	-0.16556	2.794e-14
N26	0.0813272779	0.0770384422	-0.44497	-0.33867	-1.38866	0.34960	Lesser	-0.16557	2.794e-14
N94	0.0361167819	0.0297268631	-0.88044	-0.49084	-2.13459	0.37521	Lesser	-0.19200	2.794e-14
N89	0.0288575653	0.0033433992	-1.73806	-0.68987	-3.12333	1.15221	Lesser	-0.22170	2.794e-14
N81	0.0189114331	0.0388121455	-2.88882	0.25239	-8.24049	1.48047	Lesser	-0.23439	2.794e-14
N3	0.9530953942	0.0813393227	-1.35477	-2.26619	-3.49385	1.28314	Lesser	-0.23886	2.794e-14
N107	0.0025109135	0.0002785398	-1.60961	-1.01642	-5.65109	0.32489	Lesser	-0.24183	2.794e-14
N52	0.0354521603	0.0373985556	-1.33173	-1.07283	-2.45346	0.10657	Lesser	-0.27141	2.794e-14
N84	0.0887263104	0.0575743247	-1.54758	-1.00052	-3.21635	0.27978	Lesser	-0.27708	2.794e-14
N51	0.0370455977	0.0373985556	-1.36488	-1.18307	-2.51953	0.03558	Lesser	-0.28216	2.794e-14
N122	0.0834176044	0.023392797	-1.35384	-1.03309	-2.61653	0.18901	Lesser	-0.28561	2.794e-14
N33	0.0692059045	0.069132424	-1.34930	-1.27928	-2.84055	0.00740	Lesser	-0.28721	2.794e-14
N41	0.0952232048	0.0633983762	-1.23657	-1.03895	-2.35275	-0.25130	Lesser	-0.29225	2.794e-14
N69	0.0129226217	0.0013459596	-3.20793	-3.00937	-7.89386	2.85659	Lesser	-0.29902	2.794e-14
N103	0.010507665	0.0025011338	-2.41272	-1.31376	-7.19133	0.25735	Lesser	-0.30822	2.794e-14
N127	0.4315484576	0.2255860745	-2.41584	-1.70050	-3.87251	0.28956	Lesser	-0.31157	2.794e-14
N106	0.0063599313	0.0015394503	-2.51824	-2.21792	-6.64193	-0.05271	Lesser	-0.32496	2.794e-14
N78	1.8775255193	0.1494417485	-1.82242	-1.91500	-3.41299	-0.46531	Lesser	-0.35194	2.794e-14
N64	2.9515e-06	2.6072e-06	-2.82710	-0.60027	-6.09573	0.40624	Lesser	-0.35646	2.794e-14
N32	0.0642962267	0.0305444348	-1.81638	-1.37204	-3.27328	-0.31708	Lesser	-0.35748	2.794e-14
N100	0.0545082999	0.0146844151	-1.76802	-1.37317	-2.74678	-0.45558	Lesser	-0.36637	2.794e-14
N58	0.0038449171	2.5936e-06	-3.67542	-6.19876	-6.86133	0.31225	Lesser	-0.38527	2.794e-14
N50	0.086291366	0.0373985556	-1.80356	-1.80228	-2.65327	-0.98559	Lesser	-0.40718	2.794e-14
N91	0.0155362545	0.0037254044	-2.86462	-1.67597	-4.52040	-0.38924	Lesser	-0.40731	2.794e-14
N125	0.4494789067	0.080341272	-2.29993	-2.13786	-4.05055	-0.61726	Lesser	-0.42116	2.794e-14
N108	0.9856202264	2.648e-06	-4.98832	-4.43638	-11.69155	0.38791	Lesser	-0.43359	2.794e-14
N56	2.8674e-06	2.4445e-06	-5.39314	-0.24481	-13.10529	0.31903	Lesser	-0.43398	2.794e-14
N46	0.4440380923	0.0203043672	-6.23481	-8.69454	-11.44060	0.20912	Lesser	-0.50669	2.794e-14
N96	0.023273167	0.0033109591	-4.29650	-3.04649	-8.45988	-0.90913	Lesser	-0.51784	2.794e-14
N70	0.0131326538	7.90075e-05	-5.26490	-6.64571	-8.36976	-1.92956	Lesser	-0.54026	2.794e-14
N63	0.0031578482	2.2999e-06	-5.24105	-6.56786	-7.65160	-2.68509	Lesser	-0.54140	2.794e-14
N65	0.0029718522	2.3026e-06	-5.51751	-6.47248	-8.42945	-3.19718	Lesser	-0.54848	2.794e-14
N59	0.0031905828	2.6134e-06	-6.02396	-6.25294	-11.47995	-1.26459	Lesser	-0.55698	2.794e-14
N74	0.2738246211	0.0385097942	-3.82117	-3.10868	-4.90625	-1.74793	Lesser	-0.56454	2.794e-14
N93	0.003175666	2.3414e-06	-5.08449	-6.62684	-7.25125	-1.58298	Lesser	-0.59218	2.794e-14
N66	0.0052319821	2.4638e-06	-6.94437	-7.63909	-11.11621	-5.01231	Lesser	-0.66671	2.794e-14
N57	0.0041447608	2.4445e-06	-7.62094	-6.64493	-13.10726	-5.58734	Lesser	-0.67944	2.794e-14
N60	0.0103497734	2.3085e-06	-7.03427	-7.65598	-8.24782	-6.23605	Lesser	-0.75703	2.794e-14
N55	0.0016857714	2.322e-06	-6.39177	-6.39356	-6.83594	-5.96213	Lesser	-0.75894	2.794e-14
N67	0.0047010418	2.3107e-06	-6.95513	-6.96742	-7.31186	-6.59040	Lesser	-0.79703	2.794e-14
N61	0.0128675103	2.6072e-06	-7.98406	-8.01995	-8.39432	-7.61404	Lesser	-0.86422	2.794e-14
N71	0.2484082443	2.3738e-06	-10.06260	-10.78186	-12.23950	-8.94023	Lesser	-0.87677	2.794e-14
N53	0.0125551048	2.144e-06	-8.85757	-8.41040	-10.09438	-7.92293	Lesser	-0.88241	2.794e-14