Propertites of Site partitioning Phylogeny of AK4 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N51	0.0241461977	5.0870673113	4.63657	6.02493	3.42250	6.47357	Greater	0.72682	2.882e-14
N93	2.983e-06	0.0692650996	6.23267	9.61973	1.87442	10.28844	Greater	0.70086	2.882e-14
N119	2.6695e-06	0.0084921042	4.79845	6.55410	1.17813	7.96601	Greater	0.68982	2.882e-14
N43	0.0378493817	1.3857108413	3.20336	3.58882	2.49901	4.13903	Greater	0.68546	2.882e-14
N42	0.0421785198	0.5033108755	2.89265	3.00370	1.43109	4.06094	Greater	0.65641	2.882e-14
N39	0.2820835458	1.8275994188	2.53516	2.42498	1.86971	3.27385	Greater	0.64609	2.882e-14
N69	0.0351891302	2.6734653765	3.38610	4.17496	1.10566	5.36175	Greater	0.62773	2.882e-14
N112	0.0067518911	0.377425535	4.44070	5.28836	0.95502	7.09569	Greater	0.62299	2.882e-14
N17	0.0181466489	0.0589369754	3.89134	2.10044	0.63411	9.61512	Greater	0.59402	2.882e-14
N92	0.0140675894	0.0516996717	1.77125	1.66711	0.83658	2.55257	Greater	0.53395	2.882e-14
N8	0.0859490281	1.0262382142	2.06174	2.89436	0.39214	3.31691	Greater	0.53347	2.882e-14
N55	2.1128e-06	0.005125798	3.45406	0.66662	-0.05842	6.74747	Greater	0.52488	2.882e-14
N111	0.0066147814	0.0599323753	3.83272	3.65327	0.40223	8.51154	Greater	0.51857	2.882e-14
N98	0.0009442244	0.0236429985	3.14531	1.51338	0.17783	8.49075	Greater	0.51497	2.882e-14
N94	0.0038237858	0.0062448246	2.27533	1.16056	0.07114	7.86540	Greater	0.44491	2.882e-14
N123	0.0031747469	0.0354630669	2.65512	1.57735	-0.07363	8.64605	Greater	0.43988	2.882e-14
N71	0.0110193193	0.1141585194	1.47026	1.84661	0.19527	3.95564	Greater	0.43620	2.882e-14
N96	0.0373298098	0.0670834557	0.91980	0.95953	0.32541	1.50331	Greater	0.42338	2.882e-14
N114	2.896e-06	2.852e-06	1.58228	0.46413	-0.01380	1.32718	Greater	0.42124	2.882e-14
N99	0.0248408893	0.0750249202	1.41992	1.56641	-0.40173	2.57300	Greater	0.41469	2.882e-14
N52	0.0088669463	0.0354628239	1.71765	2.02394	-0.31701	4.50507	Greater	0.41308	2.882e-14
N118	0.0035064361	0.0354638654	1.89383	1.11350	-0.38122	3.64304	Greater	0.40192	2.882e-14
N48	0.0170909349	0.2320423088	1.08369	1.57621	-0.76442	3.79675	Greater	0.37371	2.882e-14
N113	2.6553e-06	2.876e-06	1.45728	0.49903	-0.25460	6.16908	Greater	0.35425	2.882e-14
N70	0.0150941498	0.0312187333	0.65453	0.72585	-0.21087	1.41770	Greater	0.35329	2.882e-14
N129	0.0132368236	0.0635377804	1.00725	1.48810	-2.39180	2.94956	Greater	0.33445	2.882e-14
N28	2.4869e-06	0.0028428898	1.85283	0.59724	-2.29888	8.56770	Greater	0.33366	2.882e-14
N7	0.3409888428	0.386449362	1.00702	0.51851	-1.27820	3.15617	Greater	0.32759	2.882e-14
N109	2.3142e-06	2.3144e-06	0.38082	0.35790	0.09175	0.69237	Greater	0.32539	2.882e-14
N50	0.0191242672	0.0183020714	0.72694	0.28817	-0.69269	3.66561	Greater	0.30868	2.882e-14
N44	0.0554124103	0.6129119872	0.75301	0.42329	-1.33984	2.88294	Greater	0.30564	2.882e-14
N85	0.0410744098	0.6476587003	0.72493	0.59271	-1.90277	5.05238	Greater	0.28951	2.882e-14
N19	2.3231e-06	2.5368e-06	0.22049	0.24000	-0.13489	0.57133	Greater	0.28166	2.882e-14
N130	0.0072842736	0.017732797	0.54607	0.48958	-2.59492	3.03072	Greater	0.28135	2.882e-14
N53	2.3231e-06	2.4505e-06	0.21593	0.23750	-0.13575	0.56246	Greater	0.28048	2.882e-14
N47	0.0121685717	0.0119065348	1.14461	0.41523	-2.22531	5.71704	Greater	0.27246	2.882e-14
N2	0.0059123439	0.0109762495	0.51763	0.59074	-3.05017	3.97028	Greater	0.26281	2.882e-14
N65	2.7982e-06	2.5244e-06	1.03203	0.38586	-4.17834	5.64524	Greater	0.25396	2.882e-14
N58	0.3884770772	0.0355899568	0.09828	-0.01171	-2.19732	3.04259	Greater	0.23913	2.882e-14
N84	0.365075107	1.10343897	0.15305	-0.40667	-1.58378	1.87321	Greater	0.22929	2.882e-14
N12	0.0036724949	0.0028084542	0.07895	0.17848	-4.58596	2.28738	Greater	0.20577	2.882e-14
N87	0.0803597507	0.0498461325	-0.25257	-0.24480	-1.92705	1.92317	Greater	0.19919	2.882e-14
N4	0.0318214074	0.0153577813	-0.20432	-0.53166	-3.08975	4.40005	Greater	0.17499	2.882e-14
N95	0.0371337517	0.0413931177	-0.26500	-0.24812	-0.91033	0.40991	Greater	0.17400	2.882e-14
N46	0.0155765647	0.0118221177	-0.10973	0.11148	-3.10126	3.22788	Greater	0.16961	2.882e-14
N3	0.0150133891	0.0216527844	-0.54444	0.28733	-2.77254	1.63919	Greater	0.16775	2.882e-14
N6	0.0196317235	0.037793286	-0.85526	0.25721	-3.83116	1.72059	Greater	0.16347	2.882e-14
N41	0.0514778526	0.0273775944	-0.33608	-0.22536	-0.84475	0.27918	Greater	0.16242	2.882e-14
N27	0.0045432675	2.7123e-06	-0.36049	-0.02774	-5.46059	5.23097	Greater	0.15732	2.882e-14
N97	0.0372347517	0.0209725126	-0.47664	-0.24227	-1.38554	0.49864	Greater	0.15303	2.882e-14
N1	0.2465174209	0.0655237349	-0.71365	-0.44629	-2.80612	1.10853	Greater	0.13989	2.882e-14
N30	0.2752784265	0.019872342	-0.13372	-2.51461	-4.38069	2.57343	Greater	0.12333	1.76813e-12
N83	0.3742288976	0.0725840334	-1.08572	-0.50630	-2.72643	1.37111	Greater	0.11367	1.11699e-10
N110	2.7028e-06	2.7176e-06	-0.52333	0.22391	-10.37252	0.95605	Greater	0.10978	4.9512e-10
N90	0.0212770184	0.042676927	-1.18120	-0.28969	-3.56043	1.27588	Greater	0.10674	1.59827e-09
N86	0.037545809	0.0190356125	-1.23051	-1.01186	-3.53534	2.27577	Greater	0.09700	5.7792e-08
N72	0.0613419673	0.025946454	-0.77583	-0.77574	-2.05725	0.15966	Greater	0.09369	2.4016e-07
N66	0.0512244698	0.1663143523	-1.61312	1.32204	-8.39648	3.69117	Greater	0.08364	3.7155e-06
N68	0.2350143739	0.2462212209	-1.43943	-0.51919	-3.56809	1.01529	Greater	0.07935	1.28688e-05
N73	0.0059227317	0.0048767948	-1.01756	-1.43878	-3.85301	0.66910	Greater	0.07034	0.00015288
N107	2.605e-06	2.5017e-06	-1.92516	0.12494	-6.36898	0.50232	Greater	0.06055	0.0016332
N74	0.0296986468	0.0145965681	-1.27735	-0.95444	-2.92761	0.31776	Greater	0.05325	0.007711
N121	2.7509e-06	2.8531e-06	-1.34039	-0.17312	-6.58193	0.70083	Greater	0.04077	0.07117
N89	0.2926099685	0.0933025998	-1.25096	-1.15728	-2.47677	0.12255	Greater	0.04002	0.072549
N80	2.9726112195	0.1175435199	-1.53742	-1.26393	-3.19353	0.21619	Greater	0.02683	0.32046
N122	0.004276556	2.8669e-06	-1.61181	-0.60002	-6.53075	0.71442	Greater	0.02405	0.37035
N81	1.388983769	0.3996670054	-1.71803	-1.40448	-3.54965	0.41572	Greater	0.01662	0.6356
N38	0.0035487579	0.0002110666	-2.07650	-1.34646	-7.21200	3.15685	Lesser	-0.00868	0.6693
N120	0.0309240693	0.0060902426	-1.42107	-1.40762	-2.18607	-0.52242	Lesser	-0.01193	0.6693
N45	1.3836006807	0.4115796384	-1.28876	-1.36818	-2.05720	-0.58465	Lesser	-0.01381	0.6693
N76	0.3227679179	0.0141849385	-2.39542	-2.38200	-4.34525	0.89835	Lesser	-0.03616	0.118
N116	0.0036260795	2.8714e-06	-2.35345	-1.08989	-6.78300	0.29378	Lesser	-0.03621	0.118
N88	0.0277422557	0.0220374704	-2.35973	-1.54863	-3.78470	-0.26182	Lesser	-0.08838	9.1562e-07
N75	0.1605930035	0.0197634913	-2.06003	-1.94479	-3.27825	-0.96483	Lesser	-0.08872	9.432e-07
N49	0.4037973975	0.6049465384	-3.26181	-2.02683	-7.87698	1.05968	Lesser	-0.09009	5.4774e-07
N36	0.005909384	2.683e-06	-2.77131	-2.64148	-6.84847	0.20672	Lesser	-0.09458	1.2994e-07
N13	2.6624e-06	2.3207e-06	-3.08034	-0.41166	-7.13674	0.28934	Lesser	-0.09752	5.016e-08
N100	0.0777221811	0.0013984281	-2.88352	-2.24165	-6.21105	0.24302	Lesser	-0.11194	2.129e-10
N91	0.0130870912	2.7795e-06	-2.88471	-0.67323	-7.82692	0.27399	Lesser	-0.11238	1.84418e-10
N31	0.0100704351	0.0002106003	-2.72543	-2.47826	-6.66624	-0.68010	Lesser	-0.11604	4.2476e-11
N11	2.9335e-06	2.5368e-06	-3.32402	-0.64094	-7.23793	0.21977	Lesser	-0.12407	1.3095e-12
N77	0.5821355636	0.0281612765	-2.79101	-3.36079	-4.78309	-0.79703	Lesser	-0.12473	1.00161e-12
N101	0.0704581616	0.0117756434	-3.18746	-2.32541	-7.88730	0.46932	Lesser	-0.13082	5.9264e-14
N15	2.8036e-06	2.3235e-06	-3.43460	-0.87866	-7.11244	0.19903	Lesser	-0.13713	2.882e-14
N34	0.0038788445	2.6325e-06	-3.30828	-3.17695	-7.31623	0.28126	Lesser	-0.14083	2.882e-14
N20	0.0035905815	2.3246e-06	-3.50662	-6.29375	-7.12172	0.22213	Lesser	-0.14919	2.882e-14
N78	0.6067533008	0.021998089	-3.23769	-3.46036	-5.71298	-0.75311	Lesser	-0.15729	2.882e-14
N82	0.9261099547	0.0622239291	-2.96159	-3.03410	-4.89957	-1.45281	Lesser	-0.15774	2.882e-14
N23	0.0084344999	0.003779408	-3.63799	-5.12099	-7.37182	0.04604	Lesser	-0.15783	2.882e-14
N40	0.0157259184	0.0037476047	-3.38543	-2.95821	-7.02945	-0.41670	Lesser	-0.17738	2.882e-14
N67	0.0340242984	2.6172e-06	-4.18522	-7.28526	-9.07511	1.99444	Lesser	-0.19368	2.882e-14
N5	0.0460097956	0.007749534	-3.88222	-2.36059	-9.01876	-0.46026	Lesser	-0.19818	2.882e-14
N126	0.0064511564	1.12175e-05	-3.78763	-6.25390	-7.58278	0.02040	Lesser	-0.19908	2.882e-14
N59	0.0037776165	0.0008233988	-3.69610	-4.77383	-7.35771	-0.20647	Lesser	-0.19914	2.882e-14
N22	0.0039187363	2.3235e-06	-4.00572	-6.28581	-7.53861	0.01501	Lesser	-0.20078	2.882e-14
N14	0.002808861	2.3235e-06	-4.22185	-6.39431	-7.35111	0.11172	Lesser	-0.21953	2.882e-14
N35	0.0071537557	2.5124e-06	-3.97203	-3.85135	-7.51828	-0.98763	Lesser	-0.22793	2.882e-14
N79	0.2192242773	0.0446009885	-4.00152	-2.63862	-5.59059	-1.15667	Lesser	-0.23412	2.882e-14
N128	0.0256213424	0.035463955	-3.87966	-4.01411	-8.28448	-1.15877	Lesser	-0.23776	2.882e-14
N62	2.6686e-06	1.7258e-06	-4.22435	-5.58167	-7.93672	0.17744	Lesser	-0.24021	2.882e-14
N32	0.0111134511	0.0039607099	-3.83346	-2.74247	-6.56370	-1.15834	Lesser	-0.25298	2.882e-14
N16	2.7812e-06	2.3177e-06	-4.56611	-7.01880	-7.70684	0.02361	Lesser	-0.27027	2.882e-14
N57	0.025892372	2.5414e-06	-4.64338	-7.82273	-9.22513	0.48360	Lesser	-0.27303	2.882e-14
N24	0.432793652	0.0051814895	-4.49857	-4.65752	-6.34310	-1.68156	Lesser	-0.27557	2.882e-14
N54	0.0125777632	2.7678e-06	-4.39745	-7.22809	-8.14308	-0.55978	Lesser	-0.27782	2.882e-14
N131	0.2130948191	0.0355894876	-4.32947	-3.81133	-6.76536	-1.71940	Lesser	-0.29645	2.882e-14
N105	0.0177963265	0.0001874178	-4.72036	-6.13454	-8.34271	-1.07148	Lesser	-0.30660	2.882e-14
N29	0.0071883476	2.5837e-06	-5.08975	-7.08587	-7.90290	-0.05127	Lesser	-0.30676	2.882e-14
N18	0.0039495511	2.575e-06	-5.04127	-6.75346	-7.43145	-0.45505	Lesser	-0.31834	2.882e-14
N127	0.0931490236	0.0039122112	-4.93290	-4.38363	-7.72648	-2.94847	Lesser	-0.35069	2.882e-14
N104	0.1031050158	0.0001878036	-6.27687	-6.50028	-9.32824	-3.35173	Lesser	-0.47230	2.882e-14
N124	0.3637076651	0.00253572	-6.66457	-6.76681	-11.20908	-2.89216	Lesser	-0.47804	2.882e-14
N60	0.0139669524	0.0005043496	-6.13843	-7.76865	-8.30798	-2.80131	Lesser	-0.49933	2.882e-14
N33	0.018157272	2.5093e-06	-6.47428	-7.19424	-8.38028	-3.95977	Lesser	-0.52823	2.882e-14
N106	0.0073724034	2.6763e-06	-7.61162	-7.31292	-11.64426	-6.22006	Lesser	-0.53867	2.882e-14
N64	0.263479452	2.445e-06	-8.19563	-10.13042	-12.00892	-7.37948	Lesser	-0.59581	2.882e-14
N125	0.0078534052	2.9172e-06	-7.50700	-7.48418	-7.77330	-7.01908	Lesser	-0.59714	2.882e-14
N56	0.0264818437	2.8575e-06	-7.54957	-8.40784	-9.76203	-4.68273	Lesser	-0.62141	2.882e-14
N37	0.0074359666	2.5368e-06	-7.65009	-7.55360	-8.17244	-7.17460	Lesser	-0.62617	2.882e-14
N117	0.0113689243	2.3144e-06	-7.69290	-7.76215	-8.34253	-7.25311	Lesser	-0.64139	2.882e-14
N63	0.0183726369	2.3195e-06	-8.15011	-8.10674	-10.43872	-7.25923	Lesser	-0.64223	2.882e-14
N115	0.0109841899	2.6072e-06	-7.76764	-7.81716	-8.25456	-7.37366	Lesser	-0.64821	2.882e-14
N108	0.0148313117	2.5017e-06	-7.84223	-7.80938	-8.27454	-7.42108	Lesser	-0.65837	2.882e-14
N25	0.0074721371	2.314e-06	-8.64962	-7.67591	-8.94694	-7.06473	Lesser	-0.67077	2.882e-14
N21	0.007392574	2.324e-06	-7.92226	-7.92585	-8.47515	-7.46837	Lesser	-0.67104	2.882e-14
N26	0.0103445705	1.8377e-06	-7.93823	-8.10186	-8.51282	-7.58452	Lesser	-0.68038	2.882e-14
N102	0.0163260667	2.607e-06	-8.24949	-8.31999	-8.82568	-7.76103	Lesser	-0.71831	2.882e-14
N10	0.0261207667	2.5368e-06	-8.72330	-8.67547	-9.30719	-8.11712	Lesser	-0.76451	2.882e-14
N9	0.0558344785	2.5128e-06	-9.81073	-9.31606	-11.48508	-8.81574	Lesser	-0.82548	2.882e-14
N61	0.0457496009	1.7374e-06	-9.33366	-9.48401	-10.11496	-8.93680	Lesser	-0.82563	2.882e-14
N103	0.1061398827	2.6064e-06	-10.01604	-9.92623	-10.57547	-9.36630	Lesser	-0.88338	2.882e-14