Propertites of Site partitioning Phylogeny of COX4I1 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N98	2.3778e-06	0.1651892868	11.30389	11.40034	11.07632	11.65482	Greater	0.96379	2.838e-14
N109	0.0300562364	1.1464343567	6.81812	4.26160	3.28510	13.01481	Greater	0.82004	2.838e-14
N104	2.7148e-06	0.0870465347	8.03859	10.14117	4.57738	10.65847	Greater	0.79761	2.838e-14
N8	2.4064e-06	0.0432844774	7.20657	9.14343	7.04583	9.77435	Greater	0.71591	2.838e-14
N52	0.0670106835	4.4372359383	3.82553	4.46331	2.37059	5.17012	Greater	0.69042	2.838e-14
N128	2.4691e-06	0.1046603138	6.62600	9.20550	0.79221	11.26214	Greater	0.63808	2.838e-14
N99	0.026087968	0.2403939983	2.68684	2.66272	2.14722	3.20990	Greater	0.63442	2.838e-14
N72	0.0129649008	0.2370249223	4.17656	3.18109	1.38798	5.16232	Greater	0.58700	2.838e-14
N9	2.4674e-06	0.0975383621	5.32606	3.66992	1.28343	10.59158	Greater	0.58267	2.838e-14
N3	0.0103399405	0.062869355	3.75164	1.98263	1.18362	8.76484	Greater	0.53841	2.838e-14
N62	0.0012097616	0.0607129787	5.12063	7.01792	0.43942	10.06720	Greater	0.51106	2.838e-14
N130	0.0868813557	0.2634354893	1.91966	1.31943	0.85293	3.44368	Greater	0.46769	2.838e-14
N29	0.0111455977	0.0340859078	4.01121	2.56908	0.24168	9.00125	Greater	0.46111	2.838e-14
N61	0.0355135432	0.2316682502	1.76288	1.86296	0.95254	2.57738	Greater	0.45300	2.838e-14
N2	0.0294277685	0.1324007244	3.04550	2.46774	0.53204	4.75634	Greater	0.44259	2.838e-14
N15	2.1784e-06	0.0250298187	4.60140	7.78176	0.06488	9.79478	Greater	0.43238	2.838e-14
N70	0.0178049492	0.0594189783	2.33420	2.37975	0.55948	4.27625	Greater	0.41029	2.838e-14
N28	0.0303248273	0.0844644476	1.61133	1.64001	0.61188	2.64742	Greater	0.40256	2.838e-14
N7	2.3293e-06	0.0129595612	3.32347	0.56312	0.24080	9.18491	Greater	0.36416	2.838e-14
N86	0.0161201151	0.0455679961	1.47810	1.69341	0.76808	2.46395	Greater	0.36403	2.838e-14
N12	0.0541033442	0.3232429729	1.36067	1.83800	0.84826	2.40304	Greater	0.35499	2.838e-14
N42	2.063e-06	0.0405214715	3.83897	1.85628	-0.31652	11.12583	Greater	0.34146	2.838e-14
N81	0.033283733	0.0831365981	1.16221	1.20632	0.41161	1.89829	Greater	0.32027	2.838e-14
N80	0.0300946948	0.3226439646	1.44280	2.15775	-0.72433	3.05408	Greater	0.31954	2.838e-14
N56	0.5832643583	4.5369738853	1.58688	0.96429	-0.03944	2.80141	Greater	0.31717	2.838e-14
N78	0.0164911893	0.3775633998	1.62586	2.35572	-0.97811	3.39431	Greater	0.31126	2.838e-14
N75	0.0759781934	0.6484483986	2.59969	2.05371	-0.76322	4.95467	Greater	0.30619	2.838e-14
N88	0.0155174237	0.0493792515	2.01968	1.64086	-0.06898	2.98060	Greater	0.29317	2.838e-14
N82	0.0154100906	0.272649912	1.78875	2.24749	-1.17108	3.66221	Greater	0.28794	2.838e-14
N121	0.0744730199	0.2111984038	0.88582	1.12273	-0.19746	2.19310	Greater	0.23777	2.838e-14
N85	0.0635214541	0.1680509052	0.78795	0.84346	0.21947	1.40146	Greater	0.23736	2.838e-14
N34	0.0195364239	0.0799358548	1.32263	1.24752	-0.63238	2.69260	Greater	0.23445	2.838e-14
N71	0.0418867852	0.0535038817	0.85861	0.93253	-0.30462	2.22463	Greater	0.22813	2.838e-14
N14	0.0699161922	0.1453491037	0.86076	0.79256	0.09316	1.60994	Greater	0.22758	2.838e-14
N1	0.1157977192	0.1818066062	0.92666	0.79196	-0.25895	2.45581	Greater	0.22018	2.838e-14
N127	0.014111532	0.0275835229	2.02095	0.83271	-0.57768	6.39521	Greater	0.22014	2.838e-14
N79	0.0425820353	0.2845249229	0.91082	1.50019	-1.03036	2.43813	Greater	0.21412	2.838e-14
N16	0.0104484085	0.0693674589	1.53377	1.29908	-1.62462	5.26520	Greater	0.21065	2.838e-14
N69	0.042045067	0.1012344436	0.58416	0.83477	0.09908	1.45844	Greater	0.19731	2.838e-14
N5	0.0278071339	0.0716222759	0.65045	0.65293	-0.00764	1.29701	Greater	0.19302	2.838e-14
N13	0.0397424441	0.0655615214	0.60780	0.55463	0.08678	1.08556	Greater	0.18557	2.838e-14
N36	0.0088385549	0.0492496811	1.28459	1.00654	-1.81201	3.91616	Greater	0.17113	2.838e-14
N107	0.3708184937	1.1855590062	0.61028	0.88667	-0.76912	2.08485	Greater	0.17009	2.838e-14
N64	0.0666101973	0.1514573245	0.38158	1.14856	-0.87171	2.04514	Greater	0.16187	2.838e-14
N84	0.006051648	0.0354889883	2.07080	0.24369	-1.58190	8.64643	Greater	0.15038	2.838e-14
N89	0.0812273901	0.1055979937	0.45667	0.72097	-0.36896	1.41512	Greater	0.14840	2.838e-14
N20	0.0574263395	1.038155709	0.81021	0.44429	-1.41243	3.98401	Greater	0.14358	2.838e-14
N60	0.0314845328	0.0530962587	0.43019	0.60464	-0.46550	1.59712	Greater	0.12807	1.95921e-11
N95	0.0466107837	0.5685469763	0.58119	0.23085	-0.65394	2.33077	Greater	0.12693	4.32e-13
N96	0.0304946615	0.5641710968	1.30798	0.08377	-0.84007	2.56204	Greater	0.11553	1.4896e-10
N6	2.2923e-06	2.3957e-06	0.31792	0.35270	0.14614	0.52276	Greater	0.10825	2.5572e-08
N33	0.0257491704	0.1107260429	0.26776	0.55627	-1.24135	2.17309	Greater	0.10385	8.0352e-09
N83	0.047966681	0.2779718835	0.18656	0.85632	-1.41947	2.02172	Greater	0.10026	3.1276e-08
N102	0.0529431965	0.5720180326	0.37634	0.10198	-0.76550	2.11046	Greater	0.08652	3.696e-06
N76	0.0526881762	0.0720212117	0.21730	0.39547	-0.42974	1.05145	Greater	0.08514	4.8323e-06
N22	0.8439228168	1.2998775027	0.32652	0.22028	-0.98543	1.35705	Greater	0.08189	9.4996e-06
N97	0.0475865554	0.5336173505	0.29879	0.09604	-0.85855	2.20003	Greater	0.08152	1.61175e-05
N38	0.0269405209	0.03893954	0.21781	0.26483	-0.34858	0.85377	Greater	0.07531	0.00055314
N77	0.069329856	0.0498484469	0.15267	0.44834	-0.59534	1.02246	Greater	0.07199	0.00026106
N90	0.0300451003	0.0657921418	-0.07041	0.68735	-1.54971	1.77921	Greater	0.07156	0.00018468
N73	0.1461453553	0.6375776138	0.21348	-0.04280	-1.32005	1.94891	Greater	0.05707	0.0048432
N67	0.0826177154	0.0521398432	0.07637	0.31161	-0.68078	1.05811	Greater	0.05605	0.0059745
N100	0.0422390925	0.5331182142	0.21257	-0.00532	-1.26178	2.32083	Greater	0.05208	0.0137634
N111	0.1914842424	0.0486924886	0.01893	0.15711	-1.25680	1.50413	Greater	0.04094	0.076373
N126	0.0535560014	0.0877790489	0.13318	0.09043	-0.92096	1.02982	Greater	0.04078	0.09319
N39	0.0099795717	0.0094317189	0.12694	0.25728	-7.38783	0.99354	Greater	0.03705	0.11691
N74	0.1065774319	0.567989923	0.08136	-0.17462	-1.60473	2.51394	Greater	0.03663	0.11691
N125	0.0284033364	0.0982956517	-0.21242	0.15685	-2.39658	2.70733	Greater	0.03521	0
N19	0.8316316848	0.9264657934	0.11865	-0.22293	-1.54871	1.57254	Greater	0.02055	0.5425
N63	0.0617044927	0.0695121196	-0.01088	0.03855	-0.53103	0.60150	Greater	0.01074	0.824
N106	0.1977236883	0.2172843233	-0.15723	0.24492	-1.09087	0.99192	Greater	0.00792	0.824
N101	0.011283139	0.0098023058	-0.45523	0.43025	-8.03654	1.41464	Greater	0.00002	0.824
N48	1.0200486152	1.620691141	-0.03675	-0.37157	-1.08392	0.82416	Lesser	-0.01365	0.824
N35	0.0232708583	0.0496083087	-0.92507	-0.13546	-2.69366	2.07760	Lesser	-0.02661	0.32946
N24	0.0150944743	0.041452966	0.27376	-0.70167	-2.75188	2.58049	Lesser	-0.02925	0.27587
N116	0.0609766339	0.1350970301	0.02130	-0.34000	-1.89691	1.04654	Lesser	-0.04362	0.060324
N129	0.0377633337	0.0216310487	-0.21802	-0.16645	-0.77791	0.40482	Lesser	-0.04791	0.059098
N44	0.1104241462	0.0576974399	-0.70908	-0.34473	-2.68321	1.86910	Lesser	-0.05795	0.0042279
N55	0.8954877038	0.4975167677	-0.00639	-1.26372	-2.55810	2.32691	Lesser	-0.08941	1.00126e-06
N21	0.7637298582	0.7715782471	-0.69724	-0.48829	-2.34610	0.90130	Lesser	-0.09114	1.00126e-06
N87	0.0197003141	0.0273537414	-1.15960	-0.23161	-2.55769	1.10540	Lesser	-0.09507	1.52658e-07
N120	0.1681019701	0.0894875509	-0.62242	-0.38877	-1.73054	0.75840	Lesser	-0.10024	2.5572e-08
N124	0.0492015835	0.0281461348	-1.09412	-0.35835	-2.16823	0.64539	Lesser	-0.12048	1.73094e-11
N112	0.1748221963	0.0856481378	-0.52726	-0.53929	-1.26095	0.22089	Lesser	-0.12883	1.82151e-13
N68	0.0580507658	0.0371745247	-0.48993	-0.49081	-0.99978	0.03729	Lesser	-0.13490	5.5895e-13
N93	0.3553505141	0.076058251	0.38621	-2.42887	-3.66925	9.10230	Lesser	-0.13571	2.838e-14
N113	0.1495749816	0.0769331925	-1.13647	-0.40455	-2.65648	0.52398	Lesser	-0.16567	2.838e-14
N119	1.356170394	0.8830385849	-0.91826	-0.85243	-1.96495	0.26746	Lesser	-0.19209	2.838e-14
N65	0.3188478409	0.1452757822	-0.94614	-0.92491	-1.78645	0.03739	Lesser	-0.21057	2.838e-14
N47	0.119850248	0.1249734386	-1.75804	-1.46681	-3.26839	0.67580	Lesser	-0.22795	2.838e-14
N115	2.7645009329	0.3143972034	-1.30529	-1.66125	-2.89952	0.35335	Lesser	-0.24231	2.838e-14
N92	0.4398359539	0.0633602255	-1.34496	-1.63382	-2.74047	0.37520	Lesser	-0.24328	2.838e-14
N105	0.1027216307	0.0743472101	-1.68365	-1.80889	-4.22362	0.54481	Lesser	-0.25034	2.838e-14
N123	0.4118036596	0.1097943154	-1.35809	-1.23403	-2.53373	-0.01681	Lesser	-0.26185	2.838e-14
N17	0.2373855802	0.0702657513	-1.01314	-0.83148	-1.41675	-0.41613	Lesser	-0.26570	2.838e-14
N53	0.154382136	0.2481532068	-2.23205	-1.36056	-3.50621	0.39031	Lesser	-0.26807	2.838e-14
N117	0.883497739	0.2029016038	-1.28507	-1.21543	-2.22754	-0.25098	Lesser	-0.27490	2.838e-14
N4	0.0062203276	2.8503e-06	-2.71553	-0.42595	-8.06505	0.30702	Lesser	-0.27842	2.838e-14
N11	0.0105489231	2.653e-06	-3.07483	-1.19443	-8.31311	0.32940	Lesser	-0.31967	2.838e-14
N114	0.187969023	0.0581454136	-2.03178	-1.35966	-3.29509	-0.24673	Lesser	-0.33942	2.838e-14
N32	0.0136398558	2.3829e-06	-3.15706	-2.29540	-8.46322	0.26353	Lesser	-0.34174	2.838e-14
N37	0.0142333523	2.9825e-06	-3.08072	-1.05824	-8.40930	0.05151	Lesser	-0.34408	2.838e-14
N27	0.034612219	0.012457242	-3.33936	-2.18772	-7.73148	0.35269	Lesser	-0.34499	2.838e-14
N49	0.0590123309	0.067842832	-2.22737	-1.48165	-4.14407	-0.18375	Lesser	-0.34645	2.838e-14
N58	1.0385512809	0.1193579262	-1.87578	-2.21443	-3.38081	-0.62136	Lesser	-0.35958	2.838e-14
N94	0.0498360026	0.0280763196	-3.10877	-2.63063	-5.70338	0.21469	Lesser	-0.36670	2.838e-14
N23	0.0783733269	0.0290076833	-3.79325	-2.49259	-8.81779	0.21676	Lesser	-0.37957	2.838e-14
N66	0.207456282	0.1146150641	-2.47296	-2.00608	-3.59302	-0.54123	Lesser	-0.38336	2.838e-14
N59	0.5750722503	0.1400629281	-1.84238	-1.45825	-3.28999	-0.68099	Lesser	-0.38707	2.838e-14
N25	0.0276410226	0.0052353822	-4.34948	-4.40006	-9.12932	0.25503	Lesser	-0.40323	2.838e-14
N40	2.9062e-06	2.3301e-06	-4.16829	-6.27388	-8.34587	0.26338	Lesser	-0.41460	2.838e-14
N108	1.0078746455	0.0875899486	-1.90489	-1.90683	-2.94411	-0.82092	Lesser	-0.41588	2.838e-14
N50	0.0960014296	0.0503843441	-2.49448	-2.08606	-4.20613	-0.84664	Lesser	-0.42890	2.838e-14
N54	0.022359665	0.0461931697	-3.57736	-4.10142	-6.08439	-0.18902	Lesser	-0.43316	2.838e-14
N41	0.0026710397	2.2976e-06	-4.33538	-6.99964	-8.01788	0.22651	Lesser	-0.44176	2.838e-14
N45	0.0235896333	0.0137051495	-3.62846	-2.86885	-5.91684	-0.54144	Lesser	-0.45276	2.838e-14
N18	0.0960470554	0.0176024743	-4.22350	-1.73765	-9.60479	-0.34001	Lesser	-0.45329	2.838e-14
N51	0.0619369976	0.0271001498	-4.57179	-3.89907	-9.59381	-0.27998	Lesser	-0.47963	2.838e-14
N31	0.0247354578	0.0051646723	-4.05782	-3.41152	-7.28073	-0.76770	Lesser	-0.48326	2.838e-14
N10	0.0123609451	2.4825e-06	-4.69460	-7.88730	-8.45046	-0.09777	Lesser	-0.49477	2.838e-14
N26	0.0303895519	0.0051991934	-5.20302	-5.46895	-9.41427	-1.12133	Lesser	-0.50212	2.838e-14
N57	0.2325900692	0.0871282128	-3.26410	-3.18342	-4.57733	-1.53927	Lesser	-0.52666	2.838e-14
N103	0.0527793283	0.0074095239	-6.00786	-6.51829	-9.95546	-1.28123	Lesser	-0.58062	2.838e-14
N122	0.1939443077	0.0144712968	-4.82542	-3.11268	-9.80568	-1.45885	Lesser	-0.58412	2.838e-14
N118	0.2735724239	0.0611279064	-4.14859	-3.09104	-5.13566	-1.91968	Lesser	-0.60114	2.838e-14
N110	0.7828761287	0.0112294071	-4.40078	-4.09047	-5.73676	-2.25819	Lesser	-0.62221	2.838e-14
N30	0.0238848282	0.0029162502	-6.32410	-7.44883	-9.15819	-2.23819	Lesser	-0.63660	2.838e-14
N91	0.3905068273	0.0072526278	-6.51315	-5.61312	-10.02478	-2.82715	Lesser	-0.68514	2.838e-14
N43	0.0392021622	0.0020570475	-6.71935	-8.81147	-9.43459	-2.96699	Lesser	-0.72041	2.838e-14
N46	0.7650784229	0.0076785587	-6.76485	-6.12642	-8.27801	-4.53370	Lesser	-0.72116	2.838e-14