Propertites of Site partitioning Phylogeny of GHITM proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N8	0.0014261284	0.1069230282	6.39056	4.46755	3.62458	10.39008	Greater	0.73717	1.672e-14
N14	0.003236184	0.247612842	6.96007	5.15356	4.46981	11.58399	Greater	0.70506	1.672e-14
N44	2.533e-06	0.0322623874	6.80624	8.73877	2.64602	9.44244	Greater	0.64521	1.672e-14
N12	0.0037249892	0.038538251	5.31789	3.64823	2.75488	9.55614	Greater	0.60321	1.672e-14
N34	0.003561287	0.1174278801	5.83832	4.32138	2.81494	10.57897	Greater	0.59589	1.672e-14
N1	0.015217949	0.376005419	3.70180	3.55190	3.16001	4.04074	Greater	0.57991	1.672e-14
N48	0.0053273723	0.2154659717	6.39113	6.28941	2.73505	11.32582	Greater	0.56106	1.672e-14
N43	0.0035304468	0.0866986753	5.18630	4.13423	1.74942	9.16538	Greater	0.49508	1.672e-14
N2	0.0265104742	0.4839855284	3.10923	2.97836	2.65586	3.33169	Greater	0.49271	1.672e-14
N49	0.005326957	0.5128979675	5.70428	5.85898	1.40074	11.48301	Greater	0.47751	1.672e-14
N13	0.0131141996	0.3699215278	3.05164	3.24334	2.47570	3.80468	Greater	0.45625	1.672e-14
N20	0.0036966588	0.068365535	4.02968	3.02902	1.97772	5.41657	Greater	0.45587	1.672e-14
N17	2.9663e-06	0.0744310379	4.87708	3.74798	1.55608	9.67303	Greater	0.43881	1.672e-14
N46	0.0329167346	0.3026737138	2.66564	2.63873	2.14172	3.18242	Greater	0.39692	1.672e-14
N6	0.0077778474	0.1136524384	2.60275	2.58322	2.13296	3.06143	Greater	0.39332	1.672e-14
N42	0.0040394646	0.0525939628	3.81595	2.74615	1.53980	8.17687	Greater	0.37928	1.672e-14
N70	0.0065257608	0.0712279529	3.37800	2.64634	1.76095	3.91251	Greater	0.37372	1.672e-14
N27	0.0165837989	0.1959730585	2.46618	2.46412	2.11627	2.82198	Greater	0.36335	1.672e-14
N45	2.5065e-06	0.0125553366	4.32484	4.80637	0.50734	8.91372	Greater	0.34298	1.672e-14
N75	0.0094180984	0.1233392967	2.49483	2.41252	-0.88124	3.63032	Greater	0.17966	1.672e-14
N38	0.0043112726	0.0120251398	2.53613	1.39073	0.09340	7.69623	Greater	0.14162	1.672e-14
N73	0.04640017	0.4620190768	1.58644	2.03197	0.20825	2.84652	Greater	0.11360	1.03536e-10
N15	0.0037005011	0.0251192083	1.99324	1.66798	-0.56245	7.67517	Greater	0.09693	6.2458e-08
N4	0.0190141598	0.3715028856	1.52292	2.03332	-0.78501	4.86226	Greater	0.09390	1.74804e-07
N19	0.0247409165	0.1045442088	1.46070	1.54738	0.99208	2.02476	Greater	0.08823	1.1382e-06
N35	0.0204391084	0.1243444463	1.45022	1.51907	0.86322	2.14377	Greater	0.08561	5.8938e-06
N37	0.0138478367	0.0437174158	1.87064	1.26066	0.38735	2.34218	Greater	0.06930	0.00055184
N30	2.4827e-06	0.0037200446	2.01778	0.66575	-0.08671	6.67351	Greater	0.05082	0.015792
N59	0.023918277	0.0971161578	1.60086	1.00089	-0.20035	3.80944	Greater	0.04029	0.08503
N32	0.0065129537	0.0242931516	1.29118	1.35745	0.60382	1.96371	Greater	0.03334	0.3241
N28	0.0129813085	0.0257473763	1.23542	1.35401	0.52252	1.99370	Greater	0.02491	0.62523
N25	0.0168721269	0.1116183106	1.17916	1.54326	0.21152	2.24350	Greater	0.02377	0.62523
N10	0.0014732559	0.0165532563	0.93568	1.47766	-0.15256	2.85727	Greater	0.02091	0.6264
N5	0.0169823155	0.0496806335	0.84449	1.44987	-0.01455	2.70087	Greater	0.01237	0.967
N52	0.4129611567	1.8048633705	1.12405	1.09636	-0.66581	3.12130	Lesser	-0.00594	0.967
N23	0.0268894583	0.0502492869	1.12780	1.12963	0.59812	1.66084	Lesser	-0.00966	0.967
N74	0.0093217614	0.1588230661	0.91843	1.23275	-1.95334	4.38688	Lesser	-0.01011	0.967
N31	0.0039667437	0.0065381799	1.08538	1.15255	-0.89792	2.23546	Lesser	-0.01441	0.967
N65	0.1923359253	0.2927909392	1.00498	1.19943	0.31828	1.90940	Lesser	-0.02478	0.62523
N36	0.0231609109	0.0694502524	1.00986	0.94782	0.48184	1.48577	Lesser	-0.04570	0.036072
N16	0.0078018946	0.045873328	0.74002	0.92755	-0.34239	2.32721	Lesser	-0.04859	0.024583
N22	0.012180803	0.058627896	0.39574	1.22579	-0.91139	2.29752	Lesser	-0.06562	0.00061425
N56	0.1317238816	0.0748605165	0.68427	0.68745	-2.72656	3.49359	Lesser	-0.06875	0.00030515
N26	0.0120915041	0.0936201278	-0.25810	1.01546	-6.06617	3.20800	Lesser	-0.08147	8.7768e-06
N40	2.9473e-06	0.0291835537	0.88541	0.23006	-2.36312	5.65223	Lesser	-0.10089	1.52881e-08
N21	0.0043079998	0.0172181271	0.97268	-0.04867	-1.21955	7.44517	Lesser	-0.12001	6.8175e-12
N41	0.0067257675	2.8137e-06	-0.11591	0.80771	-6.34474	2.39764	Lesser	-0.12315	1.74642e-12
N71	0.0170701024	0.0281104067	0.66944	0.50729	-0.28795	1.38000	Lesser	-0.14047	1.672e-14
N61	0.0690167711	1.6062207168	0.16539	0.06480	-2.34077	2.46469	Lesser	-0.16554	1.672e-14
N63	0.9684006266	2.9887196684	0.43802	0.48263	-0.59492	1.43296	Lesser	-0.16869	1.672e-14
N29	0.0059386093	0.0065129625	-0.45342	0.61808	-6.76202	1.83925	Lesser	-0.17404	1.672e-14
N24	0.0044557188	0.0195333322	0.78678	-0.03166	-0.96046	1.35012	Lesser	-0.17710	1.672e-14
N67	0.0425568966	0.1103283589	-0.00953	0.32541	-1.52052	1.60754	Lesser	-0.18714	1.672e-14
N54	0.0530287602	0.2844783534	0.36224	0.35273	-0.60426	1.02278	Lesser	-0.20818	1.672e-14
N58	0.0222590776	0.033611895	-0.24043	0.48949	-1.11553	1.42970	Lesser	-0.21234	1.672e-14
N9	0.0191987494	0.0605583281	0.31868	0.43251	-0.47642	1.14658	Lesser	-0.21933	1.672e-14
N60	0.0559546915	0.1182557264	0.02298	0.19618	-1.50001	1.41570	Lesser	-0.22104	1.672e-14
N57	1.5288026187	1.2308680201	-0.05999	-0.05988	-1.63988	1.51870	Lesser	-0.23736	1.672e-14
N64	0.0663630991	0.2209622474	-1.05590	0.50923	-1.62405	1.46688	Lesser	-0.25917	1.672e-14
N72	0.056986713	0.0874778384	-2.05369	-0.79432	-8.68563	3.51542	Lesser	-0.26453	1.672e-14
N18	0.0363837409	0.0444618619	-0.72758	0.26265	-1.68499	1.44565	Lesser	-0.28468	1.672e-14
N3	0.0645368302	0.0503910706	-0.00568	-0.19200	-1.05818	0.62701	Lesser	-0.30221	1.672e-14
N33	0.0079464204	0.0195334314	-0.76211	-0.48549	-3.63040	1.15591	Lesser	-0.30255	1.672e-14
N69	0.0178414696	0.0587205583	-1.36044	-0.30329	-3.62868	1.06177	Lesser	-0.35125	1.672e-14
N76	0.0169855959	0.0143695803	-1.45168	-0.93673	-3.98516	1.39850	Lesser	-0.35295	1.672e-14
N50	0.0839758078	0.1098785793	-0.30231	0.02026	-0.71695	0.50903	Lesser	-0.36013	1.672e-14
N51	0.2589180596	0.0612800225	-2.34186	-1.37927	-4.92983	1.21186	Lesser	-0.39387	1.672e-14
N62	0.0296670753	0.0354175597	-0.95754	-0.53689	-1.54168	0.55412	Lesser	-0.39605	1.672e-14
N47	0.0130589223	0.0093990881	-1.62403	-1.43325	-3.63210	0.31617	Lesser	-0.41638	1.672e-14
N7	0.0096336935	0.0017501345	-2.81071	-1.38759	-7.43021	0.92834	Lesser	-0.45250	1.672e-14
N55	0.1838891707	0.0303161266	-1.50214	-0.99347	-2.96170	-0.28517	Lesser	-0.51545	1.672e-14
N53	0.0642340164	0.0297243073	-1.79268	-1.30089	-2.43017	-0.33287	Lesser	-0.52611	1.672e-14
N66	0.2567065142	0.0672062475	-1.89690	-1.79032	-2.95778	-0.75424	Lesser	-0.57372	1.672e-14
N68	0.0442337622	0.0114064158	-2.65679	-1.37948	-3.33744	-0.56052	Lesser	-0.60723	1.672e-14
N39	0.0162712185	2.8375e-06	-4.36781	-7.31881	-8.13420	-0.00581	Lesser	-0.62806	1.672e-14
N11	0.0119138295	0.0058418142	-3.94175	-3.77132	-7.64236	-0.33435	Lesser	-0.64328	1.672e-14