Propertites of Site partitioning Phylogeny of IDH2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N20	2.7752e-06	0.1034159529	7.23041	5.81670	3.95841	10.55221	Greater	0.87795	1.606e-14
N10	0.0044215367	0.102053186	5.50965	4.08894	3.11620	7.27573	Greater	0.79492	1.606e-14
N17	0.0066403542	0.1234805455	3.08251	2.99507	2.59114	3.47818	Greater	0.65896	1.606e-14
N37	0.0069586639	0.1514533258	4.35740	2.89045	1.51952	5.40273	Greater	0.61637	1.606e-14
N61	0.0148845005	0.1625445381	2.71121	2.82602	2.10200	3.44461	Greater	0.55998	1.606e-14
N14	0.0012678146	0.0096857796	4.14826	3.91760	0.76064	8.46941	Greater	0.50015	1.606e-14
N39	0.0210541449	0.1760375073	2.25194	2.17215	1.19931	3.14386	Greater	0.47124	1.606e-14
N8	0.0695698862	3.6450707514	2.41358	3.10998	0.43270	4.75978	Greater	0.43359	1.606e-14
N65	0.0162052137	0.1469717218	2.60687	2.70538	0.92221	3.89802	Greater	0.43144	1.606e-14
N12	0.0017519837	0.0084227507	3.25145	2.63746	0.10260	7.75829	Greater	0.38849	1.606e-14
N63	0.0120924537	0.0548720683	1.85359	1.92586	1.00757	2.83777	Greater	0.38548	1.606e-14
N70	0.0101820525	0.1318240104	2.13788	2.19152	0.64990	3.91538	Greater	0.36103	1.606e-14
N27	0.0282539496	0.2492191853	1.88735	2.23018	0.42342	3.45465	Greater	0.36040	1.606e-14
N4	2.7973e-06	0.0023290222	3.22682	3.32103	-0.20153	7.59081	Greater	0.35563	1.606e-14
N55	0.0261056621	0.1276305583	1.91655	2.20690	-0.08161	4.55039	Greater	0.32796	1.606e-14
N34	0.1080206953	0.274896578	1.26542	1.16224	0.62800	1.83134	Greater	0.26415	1.606e-14
N62	0.0068900172	0.0365522758	1.39693	1.66947	0.10710	2.80696	Greater	0.26348	1.606e-14
N1	0.0830059783	0.25750042	1.13745	1.13522	0.87739	1.38495	Greater	0.25733	1.606e-14
N9	0.0186539573	0.0301177651	1.49323	0.86676	0.11109	2.47066	Greater	0.24317	1.606e-14
N64	0.015875429	0.0513393501	1.15135	1.28066	0.34349	2.10891	Greater	0.23324	1.606e-14
N52	0.1925594329	0.2916259612	1.01920	0.82051	0.02534	1.77841	Greater	0.17777	1.606e-14
N45	0.327819911	0.6652627297	0.83542	0.81742	0.06021	1.72147	Greater	0.15176	1.606e-14
N58	0.0692771358	0.131408427	0.93310	1.00611	-1.08178	3.16686	Greater	0.14954	1.606e-14
N24	0.0673602809	0.1522397118	0.70344	0.89345	0.12483	1.46461	Greater	0.13121	2.814e-14
N72	0.0695276447	0.625079954	0.77639	0.58434	-0.94001	2.60941	Greater	0.10601	1.66269e-09
N18	0.0026771108	2.9048e-06	0.95381	0.30972	-4.31267	5.21486	Greater	0.09812	2.9682e-08
N3	0.069242583	0.1315310707	0.59337	0.64338	0.32541	1.00770	Greater	0.09439	1.9504e-07
N33	0.0418915837	0.093397407	0.55920	0.76121	0.08825	1.19675	Greater	0.08878	9.1616e-07
N51	0.2165320202	0.4468832222	0.54884	0.70868	-0.15763	1.42628	Greater	0.08445	3.0636e-06
N13	0.0074155826	0.0082596534	0.65300	0.61137	-1.19273	2.75030	Greater	0.08432	2.5038e-06
N71	0.0176644441	0.031218754	0.48111	0.64134	-0.82837	2.07037	Greater	0.08026	8.7626e-06
N30	0.0590499425	0.0137511677	0.43805	0.48030	-1.52729	2.78641	Greater	0.06038	0.001392
N22	0.0050653164	0.0062477494	0.54230	0.57661	-1.56767	2.36578	Greater	0.06025	0.001392
N7	0.0083298111	0.0207423546	0.18074	0.70696	-1.28356	2.48152	Greater	0.05964	0.001392
N41	0.0388396592	0.0480398072	0.03050	0.58872	-1.05088	2.20318	Greater	0.05124	0.006138
N38	0.0282267829	0.0372145037	0.23737	0.53259	-1.41548	1.72819	Greater	0.01527	0.7156
N29	0.0033121115	2.9048e-06	-0.05524	0.10963	-6.95356	3.88756	Greater	0.00301	0.8115
N2	0.3016645017	0.3559659054	0.17958	0.30995	-0.65398	1.19595	Lesser	-0.00711	0.8115
N11	0.0099009713	0.0096861823	0.00562	0.19311	-2.63641	2.32945	Lesser	-0.01015	0.8115
N35	0.0078940592	0.0122783637	-0.74435	0.42520	-6.95907	1.85692	Lesser	-0.03547	0.0818
N26	0.1151542527	0.227294791	-0.02565	0.00838	-1.17450	1.15655	Lesser	-0.05997	0.001392
N50	0.244851757	0.1746453007	-0.15461	-0.12688	-1.33255	0.96099	Lesser	-0.09153	2.6925e-07
N40	0.0475294986	0.0418216171	-0.74810	-0.09925	-1.70996	1.33295	Lesser	-0.10473	4.2984e-09
N66	0.0254789862	0.0245827137	-1.64660	-0.37930	-5.25430	2.11699	Lesser	-0.13625	1.606e-14
N6	0.0125294753	0.0084392405	-1.47165	-0.30828	-7.20084	1.29584	Lesser	-0.15862	1.606e-14
N36	0.0028667388	0.0037989727	-1.19034	-0.20305	-6.93799	0.49512	Lesser	-0.16601	1.606e-14
N43	0.1864089726	0.0866027681	-1.12286	-0.76240	-2.76615	1.20320	Lesser	-0.18786	1.606e-14
N44	0.2850764572	0.1595387745	-0.57667	-0.40238	-1.50487	0.48369	Lesser	-0.19577	1.606e-14
N5	0.0114009343	0.0072702102	-2.10238	-0.72338	-7.65331	1.32053	Lesser	-0.20165	1.606e-14
N69	0.0691795507	0.0482575209	-0.76173	-1.03111	-2.18924	0.54958	Lesser	-0.20553	1.606e-14
N25	0.0116479101	0.0065469581	-1.63610	-0.77857	-3.82771	0.96455	Lesser	-0.21333	1.606e-14
N54	0.0097582761	0.0087553646	-1.45806	-0.64227	-2.62454	0.89340	Lesser	-0.21399	1.606e-14
N47	0.5426997535	0.5665236975	-0.80758	-0.87034	-2.30849	0.65514	Lesser	-0.21610	1.606e-14
N59	0.0636784251	0.0211382012	-0.89781	-0.66363	-1.90992	0.50449	Lesser	-0.21995	1.606e-14
N49	0.135283663	0.1015281664	-0.86616	-0.79196	-2.24345	0.57217	Lesser	-0.22084	1.606e-14
N73	0.072600991	0.0564141683	-0.65325	-0.52208	-1.09536	-0.02043	Lesser	-0.25366	1.606e-14
N68	0.0227840213	0.0205154197	-1.77545	-0.98654	-3.37958	0.61935	Lesser	-0.26772	1.606e-14
N32	0.0273760935	0.0155304813	-1.10272	-0.61777	-1.78298	0.23579	Lesser	-0.26926	1.606e-14
N53	0.0074534971	0.0073122562	-2.48939	-0.99316	-7.35938	0.72826	Lesser	-0.29653	1.606e-14
N31	0.0290439093	0.0155305734	-1.70470	-0.88952	-2.42223	0.24050	Lesser	-0.31512	1.606e-14
N67	0.0310118981	0.0205150316	-2.04289	-1.10905	-3.24385	0.26043	Lesser	-0.31765	1.606e-14
N48	0.5104819982	0.2256088812	-1.26531	-1.06900	-2.56528	-0.07141	Lesser	-0.33829	1.606e-14
N42	0.0550145834	0.0279812693	-3.00906	-1.92459	-6.14162	0.66374	Lesser	-0.35407	1.606e-14
N23	0.0173835392	0.0052936714	-2.66629	-1.19578	-8.67236	-0.05169	Lesser	-0.37329	1.606e-14
N60	0.1105367366	0.0277803307	-2.89618	-1.38915	-5.02686	0.22699	Lesser	-0.38159	1.606e-14
N19	0.6098292862	0.0057055391	-3.82516	-5.15826	-6.88432	0.01948	Lesser	-0.42787	1.606e-14
N28	0.0347466311	0.0155304813	-2.63290	-1.57584	-3.86385	-0.26256	Lesser	-0.43673	1.606e-14
N16	0.0153997201	0.0054700747	-3.55557	-2.01229	-8.36990	-0.44531	Lesser	-0.46829	1.606e-14
N57	0.0556164855	0.0329488945	-3.10797	-2.11454	-4.48103	-0.53385	Lesser	-0.47030	1.606e-14
N56	0.0392912312	0.0049179779	-4.25922	-3.01435	-9.05918	-0.42156	Lesser	-0.51155	1.606e-14
N46	0.2780656548	0.0318114431	-2.85162	-2.32107	-4.04000	-0.93495	Lesser	-0.51560	1.606e-14
N21	0.0148026867	2.551e-06	-8.43189	-8.45652	-8.90430	-8.02634	Lesser	-0.89146	1.606e-14
N15	0.0246601437	2.699e-06	-8.81319	-8.72866	-9.56834	-8.23488	Lesser	-0.90922	1.606e-14