Propertites of Site partitioning Phylogeny of LETM1 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N26	0.0107020624	4.2150228829	7.30290	7.30913	6.96363	7.71668	Greater	0.92269	3.168e-14
N16	0.0028347085	0.4667322558	8.61531	7.15132	5.32274	12.29038	Greater	0.90169	3.168e-14
N114	2.6689e-06	0.0393217555	7.67237	9.19789	6.41875	9.71980	Greater	0.83621	3.168e-14
N124	2.6163e-06	0.133002279	7.17774	9.22311	3.53443	10.31886	Greater	0.69233	3.168e-14
N24	0.0031526572	0.1011127867	3.85656	3.62768	3.13921	4.23930	Greater	0.68257	3.168e-14
N129	0.0108323619	4.2023784605	6.35550	6.89722	2.84019	7.97022	Greater	0.68206	3.168e-14
N3	0.0085723998	4.061124062	4.64547	4.46173	2.54476	6.84769	Greater	0.67382	3.168e-14
N21	0.0216193262	2.2372757034	4.88098	4.66451	3.07475	6.88194	Greater	0.66053	3.168e-14
N54	0.0637201651	3.4676387434	3.72740	4.07603	3.23642	4.72451	Greater	0.61450	3.168e-14
N56	0.0116452447	1.6993162979	3.78352	3.25358	2.43448	4.99480	Greater	0.60203	3.168e-14
N17	0.0169439156	0.2657749911	3.48556	3.04214	2.08975	4.88597	Greater	0.57891	3.168e-14
N119	0.0325583599	0.2272019188	3.25957	3.81692	1.46736	4.73779	Greater	0.49497	3.168e-14
N23	0.0272898489	0.2809913176	2.91354	2.47817	2.12751	3.93975	Greater	0.47720	3.168e-14
N115	0.0063952637	0.1486870753	4.67558	2.90942	1.76207	9.13239	Greater	0.47662	3.168e-14
N133	0.0077907039	0.2737928415	2.68307	2.71448	2.12510	3.29039	Greater	0.47178	3.168e-14
N4	0.0084404331	0.0952790094	2.46220	2.44832	2.03434	2.85936	Greater	0.46225	3.168e-14
N117	0.0141000078	0.3394818979	3.26473	2.48688	1.42687	5.44571	Greater	0.45585	3.168e-14
N50	0.2512583596	3.2030500219	2.35317	2.26697	2.02785	2.59712	Greater	0.44416	3.168e-14
N142	0.0296864917	0.5156097199	2.74171	2.27323	1.69639	3.20007	Greater	0.44276	3.168e-14
N122	0.0090225111	0.1021463678	3.90219	5.17134	1.15690	7.27884	Greater	0.43327	3.168e-14
N132	0.0804070908	0.8308404589	2.29077	2.29137	2.01718	2.55846	Greater	0.43237	3.168e-14
N14	0.0100165595	1.9490190889	3.07266	2.03494	1.13227	5.59299	Greater	0.39297	3.168e-14
N43	0.001898234	0.0314792574	3.65307	2.15199	1.16460	7.52388	Greater	0.39156	3.168e-14
N123	0.0200062114	0.1210010123	3.08725	3.76294	0.51288	5.51916	Greater	0.38171	3.168e-14
N106	0.0380543836	0.2062133836	2.16761	2.04653	1.67208	2.46802	Greater	0.37040	3.168e-14
N76	0.8181769763	2.4029280074	2.05870	2.03127	1.70081	2.39655	Greater	0.35998	3.168e-14
N108	0.1728791697	0.3814968862	3.00587	2.62442	0.67284	4.07613	Greater	0.35731	3.168e-14
N59	0.0067130237	0.0091177569	3.95311	3.70024	0.25431	7.54972	Greater	0.34384	3.168e-14
N79	0.0597243287	0.3502001191	2.18411	1.90758	1.33755	3.07308	Greater	0.33727	3.168e-14
N10	0.067533184	2.3020591103	3.10113	2.78389	0.21299	6.57419	Greater	0.32123	3.168e-14
N70	0.0917837521	3.1173908015	2.42243	2.32918	1.04418	4.34249	Greater	0.31408	3.168e-14
N39	0.0054298082	0.0443353714	1.89683	1.87151	1.31403	2.50893	Greater	0.28285	3.168e-14
N37	0.0033795605	0.0741127188	2.53189	2.80035	-0.17468	3.71476	Greater	0.28263	3.168e-14
N27	0.0478233633	0.9562375543	2.39996	1.76422	0.60780	4.48250	Greater	0.26681	3.168e-14
N35	0.0074346258	0.1035655116	1.93594	1.93916	1.14106	2.69846	Greater	0.26594	3.168e-14
N18	0.0228187387	0.119250904	2.25317	1.56389	0.77289	4.26828	Greater	0.25039	3.168e-14
N80	0.0099423272	0.1051329401	2.34306	2.45487	0.35791	5.04732	Greater	0.25002	3.168e-14
N20	0.1037979834	0.4955948361	1.92357	1.62463	1.18540	2.40983	Greater	0.24737	3.168e-14
N13	0.006917705	0.0284635316	2.47688	1.49538	0.74525	5.64422	Greater	0.23927	3.168e-14
N5	0.0102700982	0.0528466397	1.68007	1.66284	1.32814	2.00960	Greater	0.23790	3.168e-14
N84	0.027489108	1.198059305	2.24339	1.81969	0.50347	4.02451	Greater	0.23456	3.168e-14
N51	0.0792435408	0.745187234	2.12876	2.17544	0.18268	3.64078	Greater	0.23047	3.168e-14
N62	0.2956964368	4.2010256392	1.79376	2.17478	0.89354	3.42574	Greater	0.22513	3.168e-14
N44	0.0062349958	0.0233628491	1.83743	1.72338	1.05007	2.41226	Greater	0.22435	3.168e-14
N134	0.0207203998	0.1106218949	1.65833	1.66869	1.10516	2.26489	Greater	0.21330	3.168e-14
N104	0.0608923694	0.5778628441	1.87324	2.59815	-0.62467	3.64704	Greater	0.20195	3.168e-14
N15	0.0085113894	1.934853213	2.04557	1.64995	0.00281	5.81237	Greater	0.19882	3.168e-14
N57	0.0342245629	3.1812059963	1.79518	1.34773	0.52967	3.85402	Greater	0.16101	3.168e-14
N113	0.0107652719	0.0277136585	1.37583	1.44415	0.95573	1.88459	Greater	0.13166	2.09001e-13
N100	0.0524405475	1.4697238368	1.59521	1.60546	-0.22880	3.38254	Greater	0.12232	4.0128e-12
N19	0.0232895398	0.1266680483	1.48941	1.33003	0.53266	2.20927	Greater	0.11504	9.3129e-11
N1	0.0173000301	0.0974655397	1.26926	1.42093	0.68036	2.08175	Greater	0.10209	3.12896e-08
N52	0.3677845568	0.2781365012	1.22872	1.52783	0.33771	2.24010	Greater	0.08739	2.3433e-06
N120	0.0059795886	0.0231477883	1.20911	1.37694	0.68318	1.95753	Greater	0.08039	5.7834e-05
N6	0.0143521453	0.0405453094	1.20492	1.20943	0.80232	1.60147	Greater	0.06851	0.00045126
N53	0.321692922	0.0746140494	0.97699	1.54879	0.25639	2.32101	Greater	0.05487	0.0094164
N25	0.0054217002	0.0245065822	1.20326	1.16735	0.48930	1.85741	Greater	0.05316	0.0158752
N75	0.1133644782	4.2167051776	0.94876	1.43396	-0.78929	3.27114	Greater	0.05242	0.0140488
N125	0.0221813148	0.1455515847	1.17172	1.08907	-0.92349	3.96401	Greater	0.04104	0.089583
N109	0.0640125912	0.2282320883	1.08736	1.13445	0.76629	1.44499	Greater	0.02854	0.47674
N38	0.026251219	0.0889684833	1.02069	1.36416	0.33363	1.69726	Greater	0.02084	0.7392
N88	0.1048468058	2.4368881852	1.01376	0.71003	-0.35788	3.02388	Lesser	-0.00112	1
N32	0.0470895505	0.1626892713	0.96127	1.17377	0.61780	1.53034	Lesser	-0.00133	1
N81	0.2338842173	4.0137413374	0.60173	1.65004	-2.38023	3.16051	Lesser	-0.00572	1
N82	0.0172981781	1.4927010329	0.34101	1.08802	-1.77435	4.35253	Lesser	-0.00596	1
N118	0.2573422808	0.0885483619	0.88370	1.25879	-1.86734	2.65043	Lesser	-0.00906	1
N69	0.1079394096	0.2780395453	0.97707	0.73406	-0.37163	2.30648	Lesser	-0.02177	0.7392
N40	0.0140767976	0.0313982737	0.94424	0.90474	0.46445	1.47925	Lesser	-0.02210	0.7392
N2	0.0446973704	0.0720888131	0.92927	1.00414	0.41213	1.51676	Lesser	-0.02375	0.7052
N116	0.0103966266	0.0387807668	0.96160	0.67039	-1.02042	4.44024	Lesser	-0.02452	0.7052
N112	0.0135728898	0.0038896368	1.24874	-0.36782	-1.63766	5.99096	Lesser	-0.03421	0.24024
N121	0.0062538286	0.0069232685	0.87773	0.85598	0.19041	1.54281	Lesser	-0.04650	0.074298
N138	0.0355649962	0.1227110406	0.86697	0.95004	0.52228	1.29759	Lesser	-0.04836	0.02775
N111	0.1787630554	0.1105767945	0.90463	0.58843	-0.58771	2.39471	Lesser	-0.05280	0.013761
N45	0.0418671379	2.1806336091	0.86155	0.78578	0.01223	1.61657	Lesser	-0.05619	0.007456
N31	0.012820369	0.0244761064	0.83778	0.86290	0.17029	1.48190	Lesser	-0.05875	0.0053944
N78	0.5843684315	1.8509031637	0.85569	0.87209	0.67526	1.06291	Lesser	-0.05959	0.0053944
N55	0.1595670153	2.1355455985	0.77171	0.31656	-0.79500	2.45663	Lesser	-0.07219	0.000176616
N85	0.1057001989	1.1570963134	0.58893	0.14544	-0.87302	2.97678	Lesser	-0.07484	8.84e-05
N11	0.0055653383	0.0500845599	0.69729	1.25576	-1.90561	2.66059	Lesser	-0.07553	7.5452e-05
N7	0.0199016692	0.0484645909	0.77227	0.78880	0.29393	1.22891	Lesser	-0.08679	8.8508e-06
N46	0.1021072356	4.1439462311	0.63360	0.52512	-0.99975	2.55683	Lesser	-0.08692	2.63697e-06
N67	0.1660631647	0.5637311578	0.54073	0.56019	-1.47905	2.65875	Lesser	-0.09153	6.1163e-07
N8	0.0078010308	0.0307830861	0.74948	1.03561	-2.44130	2.40252	Lesser	-0.10737	1.91697e-09
N94	0.2101697157	1.3177764481	0.56855	0.65767	-1.07190	1.79480	Lesser	-0.10993	7.0924e-10
N63	1.8050043785	6.0693941017	0.60793	0.63004	-0.21882	1.60016	Lesser	-0.11221	2.87805e-10
N126	0.0156388577	0.08043123	0.49127	0.18839	-1.91470	2.70487	Lesser	-0.11338	1.8216e-10
N28	0.1325642249	0.0482959731	0.37160	0.17517	-1.63145	2.24172	Lesser	-0.14169	3.168e-14
N131	0.0178451848	0.1436315265	-0.06006	0.23744	-1.68818	2.23606	Lesser	-0.15909	3.168e-14
N89	0.0773629004	1.1057293107	0.47945	0.17787	-0.81632	1.50749	Lesser	-0.16216	3.168e-14
N47	0.0656162387	4.0942315206	0.39228	0.26067	-0.86437	1.52452	Lesser	-0.16515	3.168e-14
N86	0.1049157898	0.2031188772	0.52530	0.53163	0.11464	0.94476	Lesser	-0.17248	3.168e-14
N130	0.0528159172	0.3012898958	0.45856	0.53253	0.00743	1.00837	Lesser	-0.17516	3.168e-14
N92	0.2871925971	2.3769515674	0.26172	0.33183	-1.39973	1.52435	Lesser	-0.18205	3.168e-14
N36	0.0178995495	0.0191368639	0.43052	0.48716	0.03361	0.88039	Lesser	-0.19665	3.168e-14
N139	0.0324545106	0.0559007567	0.41535	0.47362	-0.17754	0.99432	Lesser	-0.19732	3.168e-14
N65	0.0177606154	3.8901404158	-0.37092	-0.04034	-2.42981	2.11469	Lesser	-0.19821	3.168e-14
N73	0.1379245541	1.0189028535	0.28680	0.15230	-1.07776	1.37432	Lesser	-0.20140	3.168e-14
N41	0.2924974369	0.1858844678	0.12179	-0.04651	-2.10752	1.97394	Lesser	-0.20525	3.168e-14
N30	0.0173628066	0.0337015545	0.40508	0.52743	0.03689	0.88407	Lesser	-0.20533	3.168e-14
N33	0.0045878924	0.0245414509	-0.46502	0.17175	-2.09862	1.84138	Lesser	-0.20596	3.168e-14
N107	0.0661254999	0.1901317037	0.29248	0.40857	-0.34521	1.07973	Lesser	-0.21025	3.168e-14
N93	0.2403031879	0.6933790586	-0.32251	-0.16695	-2.53594	2.07470	Lesser	-0.22232	3.168e-14
N97	0.0814678214	0.1315405362	0.25000	0.48087	-0.14161	0.94485	Lesser	-0.22811	3.168e-14
N34	0.0445891188	0.1228111057	0.12304	0.31647	-1.33117	1.29144	Lesser	-0.23139	3.168e-14
N95	0.1509734	1.1761267848	-0.38915	-0.13712	-2.77981	1.90120	Lesser	-0.23873	3.168e-14
N60	0.0321996338	0.0265265492	-0.51150	-0.30829	-2.58058	1.82749	Lesser	-0.24534	3.168e-14
N61	1.1846654784	2.8014924806	0.15159	0.41993	-0.34658	0.93848	Lesser	-0.25156	3.168e-14
N66	0.035318416	0.0434539367	0.17273	-0.02474	-0.97507	0.79760	Lesser	-0.25710	3.168e-14
N74	0.1155038623	0.4859696733	0.14959	-0.13331	-0.83186	0.71077	Lesser	-0.25939	3.168e-14
N9	0.0125664218	0.0367070909	-0.05302	-0.12430	-1.42571	1.39616	Lesser	-0.25961	3.168e-14
N42	0.0085193026	0.0278940454	-0.67806	0.17678	-1.84630	1.32491	Lesser	-0.26404	3.168e-14
N136	0.0204260441	1.0173515511	-1.50350	-0.62710	-5.75028	2.33595	Lesser	-0.26482	3.168e-14
N49	1.7900307669	3.4275630795	0.27889	0.27913	0.10281	0.46307	Lesser	-0.27255	3.168e-14
N48	0.0899852954	0.1394530736	-1.82785	0.14958	-3.27826	1.41719	Lesser	-0.29343	3.168e-14
N87	0.0711988481	0.0819830453	-0.11360	-0.30321	-1.01150	0.59273	Lesser	-0.31797	3.168e-14
N22	0.0497863878	0.0580714588	-0.02733	0.13563	-0.49959	0.64369	Lesser	-0.31887	3.168e-14
N12	0.0254353843	0.0320640089	0.05382	0.17054	-0.21132	0.45333	Lesser	-0.32132	3.168e-14
N90	0.06183194	1.549003961	-0.66988	-0.77720	-2.01667	0.91376	Lesser	-0.32666	3.168e-14
N96	0.1698117208	1.1245659933	-1.39459	-0.66663	-3.59023	1.43438	Lesser	-0.32721	3.168e-14
N101	0.961315416	1.422949197	-0.63062	-0.35327	-2.86009	1.04692	Lesser	-0.32967	3.168e-14
N77	0.1264669629	3.9665479442	-1.02653	-0.96531	-2.99064	1.22583	Lesser	-0.35211	3.168e-14
N105	0.0168813522	0.0147780147	-1.64893	-0.78282	-4.92930	1.49113	Lesser	-0.35282	3.168e-14
N103	0.0899991493	0.0841877926	-1.34969	-0.20752	-3.04485	1.18744	Lesser	-0.36097	3.168e-14
N64	0.3965097038	3.9909775615	-0.34763	-0.53654	-1.50504	0.47984	Lesser	-0.36317	3.168e-14
N58	0.0511567943	0.0393005382	-0.33800	-0.42586	-1.55915	0.50818	Lesser	-0.37166	3.168e-14
N91	0.1413490664	0.2341122051	-0.35909	-0.44212	-1.17983	0.20959	Lesser	-0.37280	3.168e-14
N98	0.0689151304	0.0618279816	-0.56171	-0.20431	-1.42101	0.55032	Lesser	-0.39807	3.168e-14
N140	1.3688623613	1.3747850279	-3.67641	-0.82119	-10.94568	0.69509	Lesser	-0.45005	3.168e-14
N29	0.1469063852	0.0534385292	-0.79158	-1.28858	-1.83848	-0.21186	Lesser	-0.45529	3.168e-14
N141	1.3871319332	1.3771966805	-1.97815	-0.76240	-4.71297	0.67299	Lesser	-0.45534	3.168e-14
N144	0.4961078623	1.184744271	-1.01967	-1.44386	-2.80448	0.53898	Lesser	-0.46146	3.168e-14
N68	0.3210243247	0.0390176295	-1.19548	-1.95308	-2.80991	0.83467	Lesser	-0.46419	3.168e-14
N127	0.0075087429	0.02090885	-2.56742	-1.44496	-6.87845	0.77378	Lesser	-0.47508	3.168e-14
N143	0.2428404377	0.0477477594	-3.51094	-2.76464	-8.36728	0.55565	Lesser	-0.48249	3.168e-14
N99	0.0460476976	0.0353678136	-0.95737	-0.64432	-1.57778	0.12187	Lesser	-0.49140	3.168e-14
N71	0.2158520252	0.0718817981	-1.44873	-1.91209	-2.87337	0.19342	Lesser	-0.54731	3.168e-14
N102	0.1231346832	0.1065164108	-1.53534	-0.89016	-2.93635	-0.20173	Lesser	-0.56246	3.168e-14
N135	0.1183395417	0.0805000438	-1.09871	-0.96510	-1.68956	-0.36711	Lesser	-0.56320	3.168e-14
N137	0.4612130785	0.8899593518	-2.82213	-3.55068	-5.37119	-0.18746	Lesser	-0.59524	3.168e-14
N128	0.2057292164	2.5571e-06	-5.01182	-5.83052	-10.57225	-0.16539	Lesser	-0.61951	3.168e-14
N83	0.0628100213	0.0181567683	-3.41513	-1.89008	-6.75415	-0.67861	Lesser	-0.69579	3.168e-14
N72	0.056870967	0.0233027291	-3.16541	-2.44418	-4.31560	-0.93438	Lesser	-0.71077	3.168e-14
N110	0.0269654217	2.096e-06	-9.03427	-9.19790	-9.82588	-8.50928	Lesser	-0.96671	3.168e-14