Propertites of Site partitioning Phylogeny of MICU1 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N67	2.4377e-06	0.0371967029	9.98156	9.52896	8.88169	12.49391	Greater	0.89637	3.102e-14
N69	0.0026314939	5.9169531607	9.49829	9.32951	6.84597	13.76275	Greater	0.82235	3.102e-14
N124	0.0029269116	4.717625785	7.07304	6.64048	5.11175	7.95150	Greater	0.72751	3.102e-14
N120	0.0017683091	3.0355922569	8.09817	7.65152	4.12565	12.48315	Greater	0.72588	3.102e-14
N130	0.0607770857	3.7432646633	5.68330	5.53244	5.12469	6.07178	Greater	0.71852	3.102e-14
N66	2.4379e-06	2.3907575393	8.26885	8.77714	3.93458	13.11851	Greater	0.68600	3.102e-14
N76	2.6569e-06	0.7448806407	8.08906	9.02729	4.16299	12.91955	Greater	0.66200	3.102e-14
N35	0.0018825899	0.1543514351	6.84041	5.90919	3.48401	10.09503	Greater	0.64052	3.102e-14
N32	0.0026404602	0.1417287306	6.45527	6.55494	2.67995	9.41407	Greater	0.58207	3.102e-14
N47	0.0388819161	6.021866514	4.89037	4.97504	3.54146	6.40392	Greater	0.57526	3.102e-14
N126	0.0035663978	6.0547097399	5.54170	4.98119	3.04527	7.34021	Greater	0.57492	3.102e-14
N34	0.0028321527	0.8066764666	6.92069	6.14212	3.25361	11.97150	Greater	0.57483	3.102e-14
N119	0.1034151408	6.1124771383	4.21924	4.22998	3.30919	5.43150	Greater	0.50806	3.102e-14
N74	0.0055358085	4.6900922972	5.09894	4.92863	2.44747	6.94083	Greater	0.48371	3.102e-14
N27	0.0104594503	0.2985954469	4.22450	3.53717	2.27140	6.52951	Greater	0.46482	3.102e-14
N87	0.0023948729	0.0881611545	4.83439	3.40895	1.81085	7.74368	Greater	0.42071	3.102e-14
N26	0.0023655159	0.0969037845	4.48548	3.77439	2.24666	7.32015	Greater	0.41396	3.102e-14
N72	0.00400834	0.0775932042	4.17184	3.06072	1.75519	7.18692	Greater	0.37300	3.102e-14
N36	0.0104509189	1.0655125736	3.62339	4.27830	1.68265	6.18006	Greater	0.35893	3.102e-14
N31	0.0026429645	0.0397292057	3.72233	3.17084	2.02263	4.59675	Greater	0.35181	3.102e-14
N123	0.0287920347	2.1982274529	3.60301	3.63845	1.74491	4.69111	Greater	0.34964	3.102e-14
N91	0.0152472826	6.0379182348	3.54339	3.47178	2.01636	5.49869	Greater	0.34555	3.102e-14
N88	0.0109911747	2.8848572735	3.51817	2.70260	1.04285	6.00387	Greater	0.29857	3.102e-14
N33	0.0104486082	0.356497922	3.65860	3.29479	1.76602	5.05907	Greater	0.29840	3.102e-14
N68	0.0064160827	0.5697648132	3.58666	2.90660	1.39616	6.50014	Greater	0.28588	3.102e-14
N23	0.007878101	0.2235107233	2.74017	2.73689	2.10713	3.35915	Greater	0.27220	3.102e-14
N21	0.0224672129	0.3703614214	2.99447	2.59825	1.62600	3.84993	Greater	0.27020	3.102e-14
N102	0.8457791947	6.495027683	2.69639	2.87026	2.12772	3.48300	Greater	0.26364	3.102e-14
N86	0.0060650987	3.867308055	2.97487	2.23638	1.45953	3.84904	Greater	0.23725	3.102e-14
N83	0.0825614314	2.7333799211	2.87770	3.03310	1.18230	4.96312	Greater	0.23371	3.102e-14
N81	0.0108038962	0.1057706067	3.05707	2.43853	1.35356	4.55839	Greater	0.22810	3.102e-14
N114	0.0523834536	4.8456233498	2.91714	3.33282	0.55454	5.37154	Greater	0.22212	3.102e-14
N9	0.0206568504	3.3199250715	2.89536	2.82306	0.60250	5.82003	Greater	0.21398	3.102e-14
N70	0.2024755552	2.3390589711	3.88898	3.01557	-0.59797	7.00149	Greater	0.21263	3.102e-14
N37	0.0036738515	0.06006722	2.76740	2.49484	1.50682	3.58660	Greater	0.21252	3.102e-14
N4	0.0061381868	0.0782876052	2.75857	2.33046	1.29366	3.59171	Greater	0.21249	3.102e-14
N12	0.0039813462	0.0744905366	2.94357	2.34630	1.20601	3.73541	Greater	0.21037	3.102e-14
N78	0.004295024	0.0150456653	3.65678	2.97692	-0.43980	8.15793	Greater	0.20995	3.102e-14
N7	0.0052484909	0.0907868587	2.51600	2.51246	1.61803	3.27629	Greater	0.20427	3.102e-14
N59	0.1802254921	5.9842731412	2.91813	2.91443	0.45466	5.94966	Greater	0.19878	3.102e-14
N3	0.049890607	0.4585310316	2.40926	2.22207	1.32086	3.35437	Greater	0.17354	3.102e-14
N84	0.0083821327	2.8317127643	2.89377	2.26963	0.14564	6.41277	Greater	0.17306	3.102e-14
N14	0.0202095674	0.4725110717	2.68320	2.20080	0.64302	4.59829	Greater	0.14792	3.102e-14
N44	0.1922148571	0.4797715678	2.36765	2.28651	0.53633	4.26970	Greater	0.14046	3.102e-14
N125	0.0236419056	0.1762967548	2.15492	1.93211	1.52091	2.43799	Greater	0.13984	3.102e-14
N30	0.0204942597	0.186406927	2.38139	2.01467	1.03660	3.26043	Greater	0.13950	3.102e-14
N25	0.0072888845	0.0897396003	2.15411	2.27258	1.22450	3.24485	Greater	0.13746	3.102e-14
N50	0.0405289146	0.6161432886	2.46240	2.15482	0.37259	4.09086	Greater	0.12467	1.43637e-12
N19	0.0043208201	0.0169071508	2.52710	1.71699	0.94446	2.84915	Greater	0.12132	2.1983e-11
N46	0.0526823683	6.1006972001	2.32493	1.77798	0.52529	4.85154	Greater	0.11708	3.8147e-11
N99	0.0189340002	5.8098752926	2.52420	1.54603	0.05613	5.44229	Greater	0.10026	2.96412e-08
N16	0.0038586598	0.0716248535	1.97763	2.51125	0.47547	3.96377	Greater	0.09869	5.1282e-08
N22	0.0041551217	0.0543686893	2.22212	2.06103	-0.00659	4.60870	Greater	0.08703	2.6016e-06
N108	0.0219425814	5.8494022861	2.29882	1.50728	-0.11689	5.29773	Greater	0.08498	4.8575e-06
N8	0.0118267731	0.0940862255	1.96258	2.02262	1.05128	2.87467	Greater	0.08471	4.9952e-06
N48	0.0380719096	0.0850673997	2.04475	1.44662	0.29662	4.51898	Greater	0.06883	0.00043008
N90	0.0285757773	2.9980264466	1.82669	3.00522	-1.13166	4.74340	Greater	0.06876	0.00043008
N15	0.0045883809	0.0872394941	1.79795	2.07640	0.55241	3.34824	Greater	0.06146	0.0023793
N109	0.031795221	3.249700914	2.04937	1.65446	-0.31538	4.57469	Greater	0.05314	0.0127818
N96	1.4788303787	6.3885607447	1.72072	1.79303	0.88641	3.05081	Greater	0.04690	0.038928
N1	0.0207205491	0.2853673101	1.69519	2.14220	0.44033	3.04370	Greater	0.03641	0.18707
N51	0.0607165449	0.3898982542	1.79746	1.63664	0.40449	2.83661	Greater	0.02772	0.52811
N58	0.5319754352	6.2434774375	1.75526	1.72747	-0.21811	3.53036	Greater	0.02322	0.73431
N11	0.014399223	0.1054352375	1.68359	1.69045	0.80008	2.53944	Greater	0.02300	0.73431
N129	0.0038955973	1.2153000424	2.02359	1.32328	-0.66660	4.56343	Greater	0.01286	1
N75	0.2720911499	3.0304490224	1.60228	1.71095	0.66368	2.51591	Greater	0.01151	1
N64	0.4724055963	6.3530776018	1.63631	1.59658	-0.05466	3.51435	Greater	0.01057	1
N2	0.0097644517	0.0313147378	1.54766	1.50390	0.41532	2.89927	Greater	0.00442	1
N63	0.1804415106	3.1763711927	1.61022	1.55976	-0.73676	4.12168	Lesser	-0.00081	1
N135	0.0207300707	0.085561066	1.44863	1.42259	0.90443	2.04505	Lesser	-0.02283	0.73431
N128	0.0052145302	0.6240435967	1.37758	1.32646	-0.75604	4.53674	Lesser	-0.02316	0.73431
N29	0.0223622869	0.0825434886	1.53496	1.57074	-0.31292	3.05762	Lesser	-0.02535	0.6408
N71	0.0059238838	0.0411670766	1.19931	1.44393	-0.02897	2.86775	Lesser	-0.03221	0.31848
N57	0.1429402415	4.8647134684	1.38199	1.39234	-1.07410	3.74843	Lesser	-0.04318	0.070005
N24	0.0138768215	0.094155808	1.42197	1.32404	-0.53893	3.15635	Lesser	-0.04332	0.070005
N101	0.0676254113	0.7676185871	1.36809	1.27592	0.35377	2.37820	Lesser	-0.04877	0.031977
N98	0.1981743776	6.0051328087	1.33706	1.31961	-0.68358	3.40060	Lesser	-0.05506	0.0089984
N100	0.0987702929	5.9327765169	1.43987	0.59270	-0.36442	3.73200	Lesser	-0.05870	0.004238
N110	0.0624394154	2.8822346977	1.21729	1.05078	-0.55880	3.34846	Lesser	-0.06552	0.00091938
N62	0.0586885334	0.1757468742	1.31118	1.09979	-0.09258	2.50434	Lesser	-0.07114	0.000242975
N136	0.1792262152	5.9935283039	1.31966	0.85373	-1.22508	3.79518	Lesser	-0.07919	2.57842e-05
N85	0.0109395643	0.0198552624	1.16587	0.77637	-0.66179	3.53242	Lesser	-0.08478	4.9952e-06
N5	0.0057589969	0.0511806828	0.79362	1.41902	-0.30429	2.70681	Lesser	-0.09070	8.2584e-07
N133	0.1274368008	0.2359638194	1.20960	0.65787	0.24459	1.91149	Lesser	-0.09855	5.2416e-08
N137	0.1960712513	5.9669988815	0.96847	1.26024	-1.75288	3.62768	Lesser	-0.10672	2.66112e-09
N38	0.0202501773	0.0725018194	1.16920	0.95492	0.18267	1.81825	Lesser	-0.10702	3.738e-09
N95	0.1507068628	0.1944452327	1.03253	0.59580	-0.56214	2.83374	Lesser	-0.13146	5.892e-14
N94	0.0617606485	0.0648299058	0.88589	0.44474	-1.30279	3.53987	Lesser	-0.14442	3.102e-14
N61	0.0573668996	0.3962246639	0.72962	0.59525	-1.43026	3.15908	Lesser	-0.14733	3.102e-14
N60	0.3105989198	2.8368409129	0.54797	1.00211	-1.65262	3.11202	Lesser	-0.14861	3.102e-14
N112	0.0935157732	0.0952986673	1.00707	-0.01336	-0.72184	3.18177	Lesser	-0.15623	3.102e-14
N65	0.0159992419	0.0318304876	0.93299	0.84344	-0.61635	1.77714	Lesser	-0.15663	3.102e-14
N105	0.2828475607	6.1368583627	0.84669	0.10648	-0.80000	3.08240	Lesser	-0.15862	3.102e-14
N73	0.0051544407	0.657431703	-0.20712	-0.06828	-6.23890	5.95646	Lesser	-0.17945	3.102e-14
N116	0.0249105756	5.7457332316	0.67026	0.55436	-2.04453	2.71381	Lesser	-0.17997	3.102e-14
N42	0.0163553737	0.2004766349	0.29292	0.39650	-2.00785	3.00947	Lesser	-0.18204	3.102e-14
N6	0.002949104	0.0083531702	0.23266	0.69851	-3.38164	2.83971	Lesser	-0.18299	3.102e-14
N111	0.1556135039	2.9742922051	0.33198	0.16006	-1.65963	2.93365	Lesser	-0.20469	3.102e-14
N10	0.014449148	0.1157404964	0.33671	0.71715	-2.88575	2.42538	Lesser	-0.20789	3.102e-14
N77	0.350880303	0.052394552	0.43096	0.74201	-2.27070	2.25993	Lesser	-0.21593	3.102e-14
N141	0.1692225439	2.8892634424	0.50316	0.23686	-0.93509	2.21436	Lesser	-0.21766	3.102e-14
N18	0.0483559845	0.0694277284	0.56750	0.52491	-0.64483	1.61625	Lesser	-0.22377	3.102e-14
N107	0.2579154769	5.9889361154	0.53943	-0.43997	-1.42997	2.94541	Lesser	-0.22404	3.102e-14
N139	0.0747686192	6.0479082298	0.59451	0.14561	-1.23616	1.67593	Lesser	-0.22838	3.102e-14
N122	0.0131514318	0.0120270621	-0.27423	0.68343	-5.97346	2.08005	Lesser	-0.23258	3.102e-14
N28	0.0149860315	0.0292423568	0.37761	0.54755	-0.50169	1.58708	Lesser	-0.23258	3.102e-14
N49	0.0711741957	0.1983126016	0.55458	0.43246	-0.59615	1.45175	Lesser	-0.23296	3.102e-14
N39	0.0239355453	0.0493094916	0.08495	0.14421	-4.16801	2.78616	Lesser	-0.24196	3.102e-14
N115	0.0273173656	0.0248492752	0.31341	0.07281	-1.03916	1.33205	Lesser	-0.24399	3.102e-14
N56	0.0643648183	0.1906004397	0.14396	0.34047	-1.29087	2.06103	Lesser	-0.24686	3.102e-14
N52	0.145735836	0.3848287442	0.35334	0.37671	-0.94697	1.53610	Lesser	-0.26108	3.102e-14
N138	0.4028264318	6.0292156581	0.15576	-0.94954	-2.37028	3.13587	Lesser	-0.26794	3.102e-14
N13	0.1241655422	0.1722877986	0.34376	0.27727	-0.95279	1.28168	Lesser	-0.27176	3.102e-14
N40	0.0493973432	0.0400692321	-0.13371	0.06124	-2.83928	1.62639	Lesser	-0.29742	3.102e-14
N132	0.2144889768	3.7280382668	-0.43438	-0.96017	-2.95111	2.77565	Lesser	-0.29948	3.102e-14
N41	0.0532912177	0.0796958835	-0.51544	-0.07426	-2.21348	1.88755	Lesser	-0.30048	3.102e-14
N131	0.1462134888	0.4975959117	-0.48466	-0.57551	-2.66915	2.50829	Lesser	-0.30327	3.102e-14
N17	0.0038850032	0.006944802	-0.59696	0.08183	-5.44968	1.69456	Lesser	-0.30544	3.102e-14
N20	0.0172191505	0.0245103874	-0.16223	0.02050	-1.41962	1.25643	Lesser	-0.33377	3.102e-14
N54	0.1085148014	0.142062822	0.05340	0.00974	-1.14308	1.01622	Lesser	-0.33422	3.102e-14
N117	0.2549839479	5.9769022551	-0.14196	-0.79246	-2.03305	1.11188	Lesser	-0.35521	3.102e-14
N104	0.3420179552	6.0345233805	-0.27033	-0.41483	-1.72569	1.02099	Lesser	-0.37356	3.102e-14
N92	0.1423209416	1.5437918463	-0.16271	-0.71305	-1.55560	0.67554	Lesser	-0.37737	3.102e-14
N53	0.2627875535	2.3810330239	-0.46810	-0.99724	-2.39576	1.36197	Lesser	-0.38541	3.102e-14
N103	0.3769255201	0.5261793952	-0.47195	-0.53226	-1.87351	0.97241	Lesser	-0.39469	3.102e-14
N43	0.1820002798	0.3627349188	-0.36822	-0.41729	-1.58256	0.70120	Lesser	-0.40274	3.102e-14
N127	0.0624518224	0.0702639526	-0.86830	-0.22226	-2.86263	0.95497	Lesser	-0.41800	3.102e-14
N140	1.113170622	6.0912316711	-0.69593	-1.67582	-2.70772	1.70606	Lesser	-0.42251	3.102e-14
N93	0.1823332818	0.5674501239	-0.56458	-0.85256	-2.20405	0.45552	Lesser	-0.42599	3.102e-14
N55	0.3577917634	0.2584134328	-0.47555	-0.78462	-1.51506	0.46774	Lesser	-0.44551	3.102e-14
N45	0.3191471576	0.69569995	-0.91241	-1.49533	-2.88729	1.05073	Lesser	-0.46743	3.102e-14
N113	0.5561037662	0.0600750963	-1.31201	-2.02532	-3.73138	1.28815	Lesser	-0.47076	3.102e-14
N134	0.2446150016	0.0430291211	-1.38876	-1.63960	-3.04098	0.79985	Lesser	-0.47307	3.102e-14
N97	0.0667796783	5.8019964413	-1.65901	-1.83608	-3.50277	0.16286	Lesser	-0.52149	3.102e-14
N89	0.2485987334	0.1478982706	-1.64748	-2.51306	-3.32680	0.05415	Lesser	-0.55289	3.102e-14
N121	0.0265839694	0.0518269769	-3.03978	-2.17703	-7.60958	0.62805	Lesser	-0.56303	3.102e-14
N80	0.1600115183	0.0317974149	-1.45887	-1.62572	-2.99854	-0.33468	Lesser	-0.58114	3.102e-14
N79	0.0225768983	0.0153130174	-1.65756	-1.22584	-2.33997	-0.29787	Lesser	-0.58421	3.102e-14
N106	0.1830819376	0.1019648447	-1.57816	-1.42461	-2.39637	-0.53092	Lesser	-0.60679	3.102e-14
N118	0.0322568706	5.9676475383	-2.04933	-1.63091	-3.26954	-0.33982	Lesser	-0.61490	3.102e-14
N82	0.4970648981	0.1274906951	-1.54735	-2.09138	-2.72479	-0.72502	Lesser	-0.61507	3.102e-14