Propertites of Site partitioning Phylogeny of VARS2 proteins
Natural logarithm of 'Amino acids -' over 'Residue solvent accessibilities -' based tree branch lengths ratios;
100 iteration of random 50%-alignment jackknife

Inner branch by (daughter) node	Median of branch length from		Mean of logarithmic ratios	Median of logarithmic ratios	Q1 or 25% quantile of logarithmic ratios	Q3 or 75% quantile of logarithmic ratios	Comparing of branch ratios to general population of logarithmic ratios for Inner tree branches
	Amino acids - based tree	Residue solvent accessabilities - based tree					Difference, U-test	Cliff's delta	Normalized p-value, U-test (Holm correction for multiple tests)
N99	0.0004026158	0.0126230704	6.96553	7.84926	2.70746	8.76588	Greater	0.71799	2.53e-14
N100	0.0025153803	5.3785920028	6.02098	6.92554	2.76459	8.60535	Greater	0.68365	2.53e-14
N1	0.0193437482	1.1957385385	4.80167	4.84334	4.17292	5.72099	Greater	0.64341	2.53e-14
N98	0.0037939891	5.293571852	5.22525	6.37891	2.17478	8.09756	Greater	0.58328	2.53e-14
N95	0.0252872875	2.8953566443	4.34075	4.58102	3.05237	5.52393	Greater	0.57923	2.53e-14
N97	0.0030537462	1.4210493335	4.70506	3.44922	2.44255	7.45468	Greater	0.54950	2.53e-14
N40	0.0110157509	0.1340417379	4.72634	5.53485	2.56344	6.69941	Greater	0.54912	2.53e-14
N101	0.0016427955	0.0297300636	4.40955	3.20036	2.49987	6.27757	Greater	0.52881	2.53e-14
N93	2.4476e-06	0.0094903106	5.24439	6.93530	1.01763	8.11367	Greater	0.51163	2.53e-14
N8	0.0063346685	5.422787677	4.41030	3.98455	2.15152	7.25106	Greater	0.50160	2.53e-14
N25	0.0098035063	1.9312168378	3.75631	3.33519	2.49484	4.90817	Greater	0.48626	2.53e-14
N22	0.0053660393	2.7643583057	4.72955	7.15127	1.60857	8.33747	Greater	0.48272	2.53e-14
N63	0.261336029	5.602522118	3.42485	3.46073	2.32515	4.50069	Greater	0.44834	2.53e-14
N3	0.0213199815	1.8698831174	4.01692	4.32203	1.54975	7.36609	Greater	0.41948	2.53e-14
N44	0.3568980663	5.4506320047	3.58372	4.47372	1.44003	5.59388	Greater	0.41122	2.53e-14
N11	0.007814394	5.371585671	3.88323	3.33590	1.62428	6.70823	Greater	0.40657	2.53e-14
N81	0.0329770094	4.9603994139	3.65424	4.19885	1.39643	5.83115	Greater	0.39926	2.53e-14
N5	0.142325193	5.5475328876	3.89507	3.82504	1.42569	6.95234	Greater	0.39309	2.53e-14
N13	0.0141660892	0.1643855459	3.31995	2.81856	1.75905	5.52263	Greater	0.37931	2.53e-14
N107	0.0007173369	0.0147334244	3.59115	2.82381	1.88091	7.52715	Greater	0.37272	2.53e-14
N29	0.027536619	0.2324633479	3.32767	2.68915	1.25265	5.56792	Greater	0.35754	2.53e-14
N4	0.2053050842	2.7694396478	3.20847	3.46989	1.47558	5.25392	Greater	0.35520	2.53e-14
N71	0.0215815526	4.7598331749	3.08427	3.21659	1.58491	4.94196	Greater	0.34424	2.53e-14
N15	0.0154201602	0.754842267	3.79287	3.44175	0.84041	6.85615	Greater	0.32777	2.53e-14
N14	0.0299393449	0.3572607931	3.19181	2.59372	0.92157	5.93037	Greater	0.31308	2.53e-14
N7	0.0244888069	5.4584450809	2.92457	2.93211	1.01357	5.10039	Greater	0.27655	2.53e-14
N9	0.6110637182	5.5147991691	2.45842	2.77280	1.72798	3.53186	Greater	0.27136	2.53e-14
N17	0.0092704837	0.1528973098	2.45023	2.65409	1.30108	3.73155	Greater	0.25766	2.53e-14
N36	0.0100633542	0.6862832025	2.62150	2.42357	0.98760	5.15557	Greater	0.24246	2.53e-14
N59	1.1346338273	3.6221466654	2.16296	2.25169	1.26898	2.90356	Greater	0.22646	2.53e-14
N102	0.0158522513	5.3612365679	2.49669	1.61260	1.33757	4.19229	Greater	0.22208	2.53e-14
N6	0.0274410457	0.2472483142	2.60049	2.55855	0.61100	4.89269	Greater	0.22075	2.53e-14
N82	0.1037677688	0.7566391606	2.35052	2.56774	0.78223	4.14120	Greater	0.20595	2.53e-14
N104	0.0182184102	2.5044807956	2.55070	1.47397	0.90779	5.27460	Greater	0.19958	2.53e-14
N87	0.0295022819	3.061687721	2.53209	2.34526	0.72668	5.90956	Greater	0.19888	2.53e-14
N32	0.0194007687	4.7549714331	2.49894	2.36464	0.25538	4.82197	Greater	0.19031	2.53e-14
N94	0.0036852498	0.0218866049	1.88111	1.85016	1.45657	2.29322	Greater	0.16895	2.53e-14
N52	0.4392899528	5.3576227752	1.87441	2.26011	1.46832	2.83135	Greater	0.16756	2.53e-14
N10	0.0639914024	5.5113491956	2.14256	2.06648	-0.26403	4.11362	Greater	0.12294	2.77992e-12
N21	0.2110939091	1.8167166241	2.17741	1.78396	0.40420	4.02928	Greater	0.11663	5.3935e-11
N106	0.0048338549	0.0150688127	2.43392	1.10676	0.09050	6.09536	Greater	0.11274	2.17736e-10
N64	0.2493723291	3.175628868	1.59754	1.95102	1.15532	2.47764	Greater	0.10164	1.99328e-08
N45	0.0440013637	0.2640206152	1.75880	1.97699	-0.10278	4.45320	Greater	0.09945	3.6208e-08
N108	0.003806259	2.7771853628	2.31670	1.59182	-0.35703	6.05489	Greater	0.09733	7.581e-08
N49	0.0490433606	2.9123380266	1.47337	2.66623	-1.17037	4.64884	Greater	0.09658	9.5874e-08
N20	0.2171716562	1.8541148638	1.79970	1.50682	0.68838	4.30254	Greater	0.09215	4.2228e-07
N80	0.0350712741	5.3844719793	2.06924	1.13043	-0.42479	4.94461	Greater	0.09088	6.2712e-07
N37	0.0197737897	0.1365847051	1.79495	1.69270	-0.08890	4.39953	Greater	0.08727	1.99425e-06
N70	0.0852294729	0.3532756341	1.73626	1.41869	0.70336	2.88985	Greater	0.08606	2.7163e-06
N28	0.0150312163	0.0725137677	1.58348	1.55785	0.97724	2.11923	Greater	0.08428	4.5716e-06
N24	0.023364802	2.7352895684	1.95809	1.13753	0.54197	2.84384	Greater	0.07524	6.226e-05
N26	0.0194629006	1.8447949073	2.02600	1.02048	0.28859	4.04697	Greater	0.07449	7.2979e-05
N34	0.0098666936	0.1062342049	1.56104	1.57985	0.02712	3.10961	Greater	0.04755	0.030268
N75	0.008664769	0.0502519661	1.54097	1.23429	0.72472	1.78762	Greater	0.03389	0.2514
N83	0.0506363356	2.5253498002	1.54038	1.27322	0.51907	2.19768	Greater	0.03135	0.26901
N78	0.2356218027	5.305679093	1.25572	2.11830	-1.40363	3.24300	Greater	0.03004	0.28488
N18	0.0081620471	0.0537564389	1.04123	1.73581	-0.10352	3.28010	Greater	0.02035	0.7826
N110	0.0203385368	0.0329998697	1.50010	1.45175	-2.09795	3.91878	Greater	0.01453	0.7826
N103	0.0055229585	0.0263347928	1.72414	0.93742	-0.24507	3.85516	Greater	0.01400	0.7826
N16	0.1305089692	0.4083561159	1.44664	1.16506	-0.12439	2.85195	Greater	0.00462	0.7826
N74	0.1008107844	4.5173605606	1.51923	1.95707	-1.57125	3.18629	Lesser	-0.00464	0.7826
N35	0.0097795867	0.0318461597	1.13727	1.22217	-0.99913	3.69400	Lesser	-0.01860	0.7826
N19	0.0083132337	0.0316918661	1.16475	1.25913	0.22880	2.31154	Lesser	-0.01914	0.7826
N33	0.0114058342	0.048382529	1.25907	1.10980	0.05195	2.09495	Lesser	-0.03459	0.2079
N51	0.0119001675	0.0555629324	1.10187	1.24338	0.09993	2.33809	Lesser	-0.03551	0.19764
N2	0.0310819693	0.1874226794	1.18131	1.11821	-0.67457	2.81054	Lesser	-0.04312	0.062465
N12	0.0298982323	2.4339133295	1.22507	0.96203	-0.43216	2.40452	Lesser	-0.05335	0.010338
N23	0.0141634261	0.0435273912	1.06662	1.06193	0.59213	1.49742	Lesser	-0.05815	0.0038336
N27	0.014411811	1.7917070775	0.87003	0.93248	-1.56951	3.52926	Lesser	-0.05984	0.0027693
N55	0.1370494532	0.1865949589	0.95614	0.83680	-0.38525	2.75023	Lesser	-0.06587	0.00074322
N111	0.023127158	1.9757630325	1.12432	0.20179	-1.18329	5.05030	Lesser	-0.08274	7.0686e-06
N113	0.0070084666	0.8419219839	0.90382	0.96035	0.23938	1.69631	Lesser	-0.09208	1.99425e-06
N89	0.1379029615	5.313868638	0.87600	0.69352	-1.04642	3.54435	Lesser	-0.09385	2.4332e-07
N60	0.1105903097	0.3094310211	0.88767	0.59049	-0.34357	2.14397	Lesser	-0.11012	6.204e-10
N77	0.0253833252	2.6122794951	0.85216	0.52806	-1.26153	2.62929	Lesser	-0.12778	3.0784e-13
N50	0.0968941414	3.5302659363	0.80992	0.16761	-0.56997	2.70478	Lesser	-0.13027	9.747e-14
N79	0.1011511767	0.1523415732	0.74866	0.03125	-0.61277	2.57911	Lesser	-0.14853	2.53e-14
N39	0.071581307	2.8654080027	0.65631	0.48112	-0.55847	1.51932	Lesser	-0.16970	2.53e-14
N114	0.0289001118	0.0632827203	0.21163	1.27513	-2.17971	2.32933	Lesser	-0.17494	2.53e-14
N96	0.0056648364	1.1760862879	-0.10098	-0.30789	-4.20488	4.53052	Lesser	-0.20746	2.53e-14
N43	2.8591025326	5.41234141	-0.02548	-0.18704	-2.49120	2.86094	Lesser	-0.23517	2.53e-14
N112	0.7013803152	0.1350951766	0.11603	-0.69419	-1.89064	2.01314	Lesser	-0.24775	2.53e-14
N67	0.0732212099	0.1369632092	0.13211	0.32164	-0.77419	1.33638	Lesser	-0.25277	2.53e-14
N72	0.1693513887	0.0816602796	0.03917	-0.20613	-2.30238	1.96368	Lesser	-0.27598	2.53e-14
N76	0.0224675657	0.0445147453	0.10688	0.24001	-0.90226	1.07308	Lesser	-0.29095	2.53e-14
N69	0.0275178766	0.05653798	-0.20083	0.03731	-1.46480	1.39805	Lesser	-0.29149	2.53e-14
N62	1.1756303353	2.0236811766	0.08682	0.35540	-0.59986	0.93851	Lesser	-0.29639	2.53e-14
N86	2.6830733924	2.6237801273	-0.37772	-0.05953	-3.42107	1.31321	Lesser	-0.30712	2.53e-14
N61	0.2338908236	0.2370649672	0.06407	-0.15722	-0.87553	0.80787	Lesser	-0.31394	2.53e-14
N115	2.6688345861	2.6986709622	-0.26885	0.16437	-2.07977	1.17856	Lesser	-0.31650	2.53e-14
N38	0.5264297461	0.0669345018	-0.46644	-0.07480	-2.99572	1.40510	Lesser	-0.33094	2.53e-14
N105	0.0067727405	0.0096056115	0.04602	0.11682	-0.39524	0.57374	Lesser	-0.33818	2.53e-14
N88	0.8096966398	4.8057239105	-0.49837	-1.09260	-3.10229	1.85089	Lesser	-0.34618	2.53e-14
N53	0.0343344197	0.0355793608	-0.30412	-0.17347	-1.96481	0.98722	Lesser	-0.35193	2.53e-14
N42	0.0677414178	2.4650601418	-0.51515	-0.40733	-2.46100	1.15350	Lesser	-0.35760	2.53e-14
N90	0.3180721171	0.0443482744	-0.74001	-0.77216	-3.08037	0.77657	Lesser	-0.38627	2.53e-14
N46	0.0869114684	1.5156956243	-0.62682	-0.83713	-1.90705	0.46793	Lesser	-0.40582	2.53e-14
N84	0.0808104644	0.0547139462	-0.85247	-0.54899	-1.90619	0.61510	Lesser	-0.40697	2.53e-14
N68	0.0496443121	0.0563747191	-0.75917	-0.40752	-1.70792	0.64385	Lesser	-0.41355	2.53e-14
N92	0.0025582679	0.0032808697	-1.59316	-0.32546	-6.03527	1.02246	Lesser	-0.42023	2.53e-14
N48	0.692671437	0.0844957285	-1.17312	-1.27027	-3.55292	0.93666	Lesser	-0.43520	2.53e-14
N66	0.0464630392	0.051215384	-1.05679	-0.79917	-2.31160	0.56330	Lesser	-0.44160	2.53e-14
N73	0.0043262093	0.0040656408	-1.30057	-0.57218	-2.35058	0.33214	Lesser	-0.46790	2.53e-14
N41	0.1473563605	0.1129829877	-0.87317	-0.65105	-1.92341	0.29152	Lesser	-0.48692	2.53e-14
N47	0.0436266719	0.0420243596	-0.73274	-0.62218	-1.31065	-0.00482	Lesser	-0.48803	2.53e-14
N65	0.0940437611	0.0672895725	-0.98855	-0.76907	-1.99190	-0.02216	Lesser	-0.49232	2.53e-14
N109	0.0047955569	0.0022170473	-2.39822	-1.75394	-6.07714	0.70171	Lesser	-0.49944	2.53e-14
N31	0.5443073675	1.8637604771	-1.49248	-1.61619	-3.86388	0.37806	Lesser	-0.50109	2.53e-14
N58	0.0897436032	0.0342877663	-1.90199	-1.15985	-3.28344	0.33847	Lesser	-0.50268	2.53e-14
N57	0.0562884451	0.0324459435	-0.99903	-0.95380	-1.93879	-0.17815	Lesser	-0.53335	2.53e-14
N85	0.7599095754	0.0849806832	-1.48990	-1.86344	-3.28679	-0.00739	Lesser	-0.53893	2.53e-14
N56	0.269219009	0.0176908317	-1.73201	-1.96575	-3.50715	0.13350	Lesser	-0.55357	2.53e-14
N30	0.2362294333	0.0169767714	-1.96025	-2.32839	-4.49004	0.40483	Lesser	-0.56337	2.53e-14
N91	0.004927205	0.0041492883	-2.94432	-1.98719	-6.38732	0.21366	Lesser	-0.63076	2.53e-14
N54	0.0862754344	0.0064378849	-3.07947	-2.43003	-4.07033	-1.05623	Lesser	-0.70812	2.53e-14